Abstract
Women with low body weight, or those who lose more than 10% of their body weight, have an increased risk of osteoporosis (1–2). In obese women, bone mineral density (BMD) is increased (3). A moderate weight loss of 10 to 14% (with adequate dietary calcium) over a 2 to 6 month period results in a 2 to 6% reduction in BMD (4–7). This bone loss is more than double the expected annual rate of loss for weight-stable postmenopausal women (8). Postmenopausal women are at greater risk of osteoporosis. Hence, weight loss in this population is of particular concern. The mechanisms underlying a reduction in BMD and the effects of a hypocaloric diet on the direction and extent of alteration in bone resorption and formation are not clear. In this study we serially monitored bone turnover in obese postmenopausal women to determine whether bone is mobilized during caloric restriction.
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© 1998 Springer-Verlag New York, Inc.
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Shapses, S.A., Heymsfield, S.B., Ricci, T.A. (1998). Voluntary Weight Reduction Increases Bone Turnover and Loss. In: Burckhardt, P., Dawson-Hughes, B., Heaney, R.P. (eds) Nutritional Aspects of Osteoporosis. Proceedings in the Serono Symposia USA Series. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-2228-6_19
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DOI: https://doi.org/10.1007/978-1-4612-2228-6_19
Publisher Name: Springer, New York, NY
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