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Pathology of Gynecologic Cancer

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Management of Gynecological Cancers in Older Women

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Abstract

This chapter will discuss the basic pathology of select gynecologic malignancies that occur in older women. First, endometrial cancer will be reviewed, including endometrioid carcinoma, the most common subtype, as well as less common entities such as serous and undifferentiated carcinoma and MMMT. Tamoxifen-associated endometrial cancer as well as Lynch syndrome, an important disorder in endometrial as well as ovarian cancer, will be briefly touched upon. Next, ovarian epithelial malignancies will be discussed with special attention to serous carcinoma and its association with BRCA abnormalities. Endometrioid, clear cell, and mucinous ovarian neoplasms will also be briefly discussed. Finally, the most common carcinomas of the cervix and vulva are reviewed.

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Authors and Affiliations

  1. Department of Pathology, Memorial Sloan-Kettering Cancer Center, 1275 York Ave, New York, NY, 10065, USA

    Deborah DeLair M.D.

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  1. Deborah DeLair M.D.
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Correspondence to Deborah DeLair M.D. .

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  1. Memorial Sloan-Kettering Cancer Center, Commack Road, Commack, 11725, New York, USA

    Stuart M. Lichtman

  2. University of Liverpool, St Helens Teach, Marshalls Cross Road, St Helens, WA9 3DA, United Kingdom

    Riccardo A. Audisio

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DeLair, D. (2013). Pathology of Gynecologic Cancer. In: Lichtman, S., Audisio, R. (eds) Management of Gynecological Cancers in Older Women. Springer, London. https://doi.org/10.1007/978-1-4471-4605-6_2

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