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Changing Views of NREM Sleep Homeostatic Regulation

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Dynamic Structure of NREM Sleep

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Abstract

The homeostatic sleep regulation idea underwent important development. Sleep homeostasis was first connected to the duration of the preceding awake time. Due to increasing innovative research in this field with convincing evidences on local sleep regulation, it seems that beyond the length of waking time, use-dependent afferent stimulation and synaptic upscaling (learning) are the main factors regulating the NREM sleep slow-wave activity (SWA). Further achievement of the same research line was to obtain evidences that plastic modulation of local slow-wave power during NREM sleep is closely related to the recreation of cognitive functions in the cortex, mainly in the frontal lobes. Slow-wave homeostasis and use-dependent plasticity are probably two sides of the same coin representing the biological function of slow-wave sleep.

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Authors and Affiliations

  1. Institute of Experimental Medicine and Institute of Neuroscience, Budapest, Hungary

    Péter Halász M.D., Ph.D., DSCi

  2. Semmelweis University Institute of Behavioral Science, Budapest, Hungary

    Róbert Bódizs Ph.D.

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  1. Péter Halász M.D., Ph.D., DSCi
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  2. Róbert Bódizs Ph.D.
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© 2013 Springer-Verlag London

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Halász, P., Bódizs, R. (2013). Changing Views of NREM Sleep Homeostatic Regulation. In: Dynamic Structure of NREM Sleep. Springer, London. https://doi.org/10.1007/978-1-4471-4333-8_5

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  • DOI: https://doi.org/10.1007/978-1-4471-4333-8_5

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  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-4332-1

  • Online ISBN: 978-1-4471-4333-8

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