Malignant Bone Tumors: From Ewing’s Sarcoma to Osteosarcoma

Abstract

Primitive malignant bone tumors are rare as they represent less than 1% of all cancers. Osteosarcoma and Ewing’s sarcoma occur the most frequently. They affect, in particular, older children, adolescents, and young adults. For many years these tumors could be controlled locally (often involving an amputation) by radical surgery accompanied or not by radiotherapy, depending on the histological type. Unfortunately, most of the patients died within two years from secondary lesions in the lung.