Skip to main content

Gabapentin

  • Chapter
  • First Online:
Antiepileptic Drug Interactions
  • 1463 Accesses

Abstract

Gabapentin (Fig. 1) corresponds chemically to 1-(aminomethyl)-cyclohexaneacetic acid with an empirical formula of C9H17NO2 and a molecular weight of 171.23.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Radulovic LL, Wilder BJ, Leppik IE, Bockbrader HN, Chang T, Posvar EL, Sedman AJ, Uthman BM, Erdman GR. Lack of interaction of gabapentin with carbamazepine and valproate. Epilepsia. 1994;35:155–61.

    Article  PubMed  CAS  Google Scholar 

  2. Falcao A, Fuseau E, Nunes T, Almeida L, Soares-da-Silva P. Pharmacokinetics, drug interactions and exposure-response relationships of eslicarbazepine acetate in adult patients with partial-onset seizures: population pharmacokinetic and pharmacokinetic/pharmacodynamic analysis. CNS Drugs. 2012;26:79–91.

    Article  PubMed  CAS  Google Scholar 

  3. Sachdeo R. Lacosamide. In: Shorvon SD, Perucca E, Engel J, ­editors. The treatment of epilepsy. 3rd ed. Oxford: Blackwell Publishing. 2009:527-34.

    Google Scholar 

  4. Perucca E, Baltes E, Ledent E. Levetiracetam: absence of pharmacokinetic interactions with other antiepileptic drugs (AEDs). Epilepsia. 2000;41(Suppl):150.

    Google Scholar 

  5. Hooper WD, Kavanagh MC, Herkes GK, Eadie MJ. Lack of a pharmacokinetic interaction between phenobarbitone and gabapentin. Br J Clin Pharmacol. 1991;31:171–4.

    Article  PubMed  CAS  Google Scholar 

  6. Graves NM, Holmes GB, Leppik IE, et al. Pharmacokinetics of gabapentin in patients treated with phenytoin. Pharmacotherapy. 1989;9:196.

    Google Scholar 

  7. Ben-Menachem E. Pregabalin pharmacology and its relevance to clinical practice. Epilepsia. 2004;45 (Suppl 6):13–18.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 2013 Springer-Verlag London

About this chapter

Cite this chapter

Patsalos, P.N. (2013). Gabapentin. In: Antiepileptic Drug Interactions. Springer, London. https://doi.org/10.1007/978-1-4471-2434-4_8

Download citation

  • DOI: https://doi.org/10.1007/978-1-4471-2434-4_8

  • Published:

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-2433-7

  • Online ISBN: 978-1-4471-2434-4

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics