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Peutz–Jeghers Syndrome

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Hereditary Colorectal Cancer

Part of the book series: M.D. Anderson Solid Tumor Oncology Series ((MDA,volume 5))

Abstract

Peutz-Jeghers Syndrome is an autosomal dominant syndrome characterized by hamartomatous gastrointestinal polyps and mucocutaneous melanin pigmentation. Patients are also at risk for extraintestinal neoplasms. In this chapter, the clinicopathologic characteristics of the syndrome, its management and surveillance recommendations will be discussed.

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Acknowledgments

We are indebted to Ms. Linda Welch for technical support. Supported in part by The John G. Rangos, Sr. Charitable Foundation, The Clayton Fund, and NIH grant 5P50CA062924.

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Authors and Affiliations

  1. Department of Medicine, The Johns Hopkins School of Medicine, Baltimore, MD, USA

    Francis M. Giardiello

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  1. Francis M. Giardiello
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Correspondence to Francis M. Giardiello .

Editor information

Editors and Affiliations

  1. M.D. Anderson Cancer Center, Surgical Oncology, The University of Texas, Holcombe Blvd. 1515, Houston, 77030, Texas, USA

    Miguel A. Rodriguez-Bigas

  2. Associate Professor of Surgery, Brazilian Registry of Inherited, Colorec, University of São Paulo Medical School, Sao Paulo, Brazil

    Raul Cutait

  3. M.D. Anderson Cancer Center, Gastroenterology, The University of Texas, Houston, 77030, Texas, USA

    Patrick M. Lynch

  4. Cancer Research UK London Research Insti, Molecular and Population Genetics Labora, London, United Kingdom

    Ian Tomlinson

  5. Medical Center, Gastroenterology, Leiden University, Leiden, 2333 AA, Netherlands

    Hans F.A. Vasen

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Giardiello, F.M. (2010). Peutz–Jeghers Syndrome. In: Rodriguez-Bigas, M., Cutait, R., Lynch, P., Tomlinson, I., Vasen, H. (eds) Hereditary Colorectal Cancer. M.D. Anderson Solid Tumor Oncology Series, vol 5. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-6603-2_20

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  • DOI: https://doi.org/10.1007/978-1-4419-6603-2_20

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