Skip to main content

Enteral and Parenteral Nutrition

  • Chapter
  • First Online:
Geriatric Gastroenterology

Abstract

Malnutrition is more common in geriatric population because of higher incidence of chronic disability and disease, but the principles of nutritional support are the same as those for any adult. Nutrition support should be implemented in a step-wise fashion, starting with dietary consultation with a nutritionist with recommendations for dietary change or supplementation. If this fails, nasogastric feeding should be considered. In the presence of anatomic changes in the upper gastrointestinal tract, a more distal postpyloric feeding tube should be considered. Intestinal failure is the only absolute indication for parenteral feeding, but initial PN supplementation may be necessary in the critically ill depleted patient while awaiting enteral feeding (EN). In the vast majority of patients, a simple low-cost polymeric formula will meet EN requirements. Extra care should be taken in the elderly terminal patient to avoid long-term “forced feeding,” whether it be EN, PN, or via gastrostomy, as these interventions are associated with poor outcomes and may actually impair the remaining quality of life.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 189.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 249.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Rolls BJ. Do chemosensory changes influence food intake in the elderly? Physiol Behav. 1999;66(2):193–7.

    Article  PubMed  CAS  Google Scholar 

  2. Parker BA, Chapman IM. Food intake and ageing—the role of the gut. Mech Ageing Dev. 2004;125(12):859–66.

    Article  PubMed  CAS  Google Scholar 

  3. Horowitz M, Maddern GJ, Chatterton BE, et al. Changes in gastric emptying rates with age. Clin Sci (Lond). 1984;67(2):213–8.

    CAS  Google Scholar 

  4. Silver AJ, Morley JE, Strome LS, et al. Nutritional status in an academic nursing home. J Am Geriatr Soc. 1988;36(6):487–91.

    PubMed  CAS  Google Scholar 

  5. Bernstein LH, Shaw-Stiffel TA, Schorow M, et al. Financial implications of malnutrition. Clin Lab Med. 1993;13(2):491–507.

    PubMed  CAS  Google Scholar 

  6. Ferguson RP, O’Connor P, Crabtree B, et al. Serum albumin and prealbumin as predictors of clinical outcomes of hospitalized elderly nursing home residents. J Am Geriatr Soc. 1993;41(5):545–9.

    PubMed  CAS  Google Scholar 

  7. Abbasi AA, Rudman D. Undernutrition in the nursing home: prevalence, consequences, causes and prevention. Nutr Rev. 1994;52(4):113–22.

    Article  PubMed  CAS  Google Scholar 

  8. Edington J, Kon P. Prevalence of malnutrition in the community. Nutrition. 1997;13(3):238–40.

    Article  PubMed  CAS  Google Scholar 

  9. Marton KI, Sox Jr HC, Krupp JR. Involuntary weight loss: diagnostic and prognostic significance. Ann Intern Med. 1981;95(5):568–74.

    PubMed  CAS  Google Scholar 

  10. Rabinovitz M, Pitlik SD, Leifer M, et al. Unintentional weight loss. A retrospective analysis of 154 cases. Arch Intern Med. 1986;146(1):186–7.

    Article  PubMed  CAS  Google Scholar 

  11. Bilbao-Garay J, Barba R, Losa-Garcia JE, et al. Assessing clinical probability of organic disease in patients with involuntary weight loss: a simple score. Eur J Intern Med. 2002;13(4):240–5.

    Article  PubMed  Google Scholar 

  12. Thompson MP, Morris LK. Unexplained weight loss in the ambulatory elderly. J Am Geriatr Soc. 1991;39(5):497–500.

    PubMed  CAS  Google Scholar 

  13. Lankisch P, Gerzmann M, Gerzmann JF, et al. Unintentional weight loss: diagnosis and prognosis. The first prospective follow-up study from a secondary referral centre. J Intern Med. 2001;249(1):41–6.

    Article  PubMed  CAS  Google Scholar 

  14. Huffman GB. Evaluating and treating unintentional weight loss in the elderly. Am Fam Physician. 2002;65(4):640–50.

    PubMed  Google Scholar 

  15. Lin HW, Li CM, Lee YC, et al. Differences in diagnostic approach between family physicians and other specialists in patients with unintentional body weight loss. Fam Pract. 1999;16(6):586–90.

    Article  PubMed  CAS  Google Scholar 

  16. Morley JE, Kraenzle D. Causes of weight loss in a community nursing home. J Am Geriatr Soc. 1994;42(6):583–5.

    PubMed  CAS  Google Scholar 

  17. Brozek J. Effects of generalized malnutrition on personality. Nutrition. 1990;6(5):389–95.

    PubMed  CAS  Google Scholar 

  18. Marcus EL, Berry EM. Refusal to eat in the elderly. Nutr Rev. 1998;56(6):163–71.

    Article  PubMed  CAS  Google Scholar 

  19. Mueller C, Compher C, Ellen DM. A.S.P.E.N. clinical guidelines: nutrition screening, assessment, and intervention in adults. JPEN J Parenter Enteral Nutr. 2011;35(1):16–24.

    Article  PubMed  Google Scholar 

  20. Kirby DF, Delegge MH, Fleming CR. American Gastroenterological Association technical review on tube feeding for enteral nutrition. Gastroenterology. 1995;108(4):1282–301.

    Article  PubMed  CAS  Google Scholar 

  21. Horton WL, Colwell DL, Burlon DT. Experience with percutaneous endoscopic gastrotomy in a community hospital. Am J Gastroenterol. 1991;86(2):168–70.

    PubMed  CAS  Google Scholar 

  22. Finucane P, Aslan SM, Duncan D. Percutaneous endoscopic gastrostomy in elderly patients. Postgrad Med J. 1991;67(786):371–3.

    Article  PubMed  CAS  Google Scholar 

  23. Debaveye Y, Van den Berghe G. Risks and benefits of nutritional support during critical illness. Annu Rev Nutr. 2006;26:513–38.

    Article  PubMed  CAS  Google Scholar 

  24. Nyswonger GD, Helmchen RH. Early enteral nutrition and length of stay in stroke patients. J Neurosci Nurs. 1992;24(4):220–3.

    Article  PubMed  CAS  Google Scholar 

  25. Broadley S, Croser D, Cottrell J, et al. Predictors of prolonged dysphagia following acute stroke. J Clin Neurosci. 2003;10(3):300–5.

    Article  PubMed  CAS  Google Scholar 

  26. Angus F, Burakoff R. The percutaneous endoscopic gastrostomy tube. Medical and ethical issues in placement. Am J Gastroenterol. 2003;98(2):272–7.

    PubMed  Google Scholar 

  27. Sanders DS, Carter MJ, D’Silva J, et al. Survival analysis in percutaneous endoscopic gastrostomy feeding: a worse outcome in patients with dementia. Am J Gastroenterol. 2000;95(6):1472–5.

    Article  PubMed  CAS  Google Scholar 

  28. Braunschweig CL, Levy P, Sheean PM, et al. Enteral compared with parenteral nutrition: a meta-analysis. Am J Clin Nutr. 2001;74(4):534–42.

    PubMed  CAS  Google Scholar 

  29. Heyland DK, MacDonald S, Keefe L, et al. Total parenteral nutrition in the critically ill patient: a meta-analysis. JAMA. 1998;280(23):2013–9.

    Article  PubMed  CAS  Google Scholar 

  30. Jeejeebhoy KN. Enteral nutrition versus parenteral nutrition—the risks and benefits. Nat Clin Pract Gastroenterol Hepatol. 2007;4(5):260–5.

    Article  PubMed  Google Scholar 

  31. Zaloga GP. Parenteral nutrition in adult inpatients with functioning gastrointestinal tracts: assessment of outcomes. Lancet. 2006;367(9516):1101–11.

    Article  PubMed  Google Scholar 

  32. Hebuterne X, Schneider S, Peroux JL, et al. Effects of refeeding by cyclic enteral nutrition on body composition: comparative study of elderly and younger patients. Clin Nutr. 1997;16(6):283–9.

    Article  PubMed  CAS  Google Scholar 

  33. Schneider SM, Al-Jaouni R, Pivot X, et al. Lack of adaptation to severe malnutrition in elderly patients. Clin Nutr. 2002;21(6):499–504.

    Article  PubMed  Google Scholar 

  34. American Gastroenterological Association medical position statement: guidelines for the use of enteral nutrition. Gastroenterology. 1995;108(4):1280–1.

    Google Scholar 

  35. O’Keefe SJ. A guide to enteral access procedures and enteral nutrition. Nat Rev Gastroenterol Hepatol. 2009;6(4):207–15.

    Article  PubMed  Google Scholar 

  36. Marik PE, Zaloga GP. Early enteral nutrition in acutely ill patients: a systematic review. Crit Care Med. 2001;29(12):2264–70.

    Article  PubMed  CAS  Google Scholar 

  37. Gray R, Tynan C, Reed L, et al. Bedside electromagnetic-guided feeding tube placement: an improvement over traditional placement technique? Nutr Clin Pract. 2007;22(4):436–44.

    Article  PubMed  Google Scholar 

  38. O’Keefe SJ, Foody W, Gill S. Transnasal endoscopic placement of feeding tubes in the intensive care unit. JPEN J Parenter Enteral Nutr. 2003;27(5):349–54.

    Article  PubMed  Google Scholar 

  39. Lewis SJ, Franco S, Young G, et al. Altered bowel function and duodenal bacterial overgrowth in patients treated with omeprazole. Aliment Pharmacol Ther. 1996;10(4):557–61.

    Article  PubMed  CAS  Google Scholar 

  40. Malone AM. Specialized enteral formulas in acute and chronic pulmonary disease. Nutr Clin Pract. 2009;24(6):666–74.

    Article  PubMed  Google Scholar 

  41. Ceriello A, Lansink M, Rouws CH, et al. Administration of a new diabetes-specific enteral formula results in an improved 24 h glucose profile in type 2 diabetic patients. Diabetes Res Clin Pract. 2009;84(3):259–66.

    Article  PubMed  CAS  Google Scholar 

  42. Rushdi TA, Pichard C, Khater YH. Control of diarrhea by fiber-enriched diet in ICU patients on enteral nutrition: a prospective randomized controlled trial. Clin Nutr. 2004;23(6):1344–52.

    Article  PubMed  CAS  Google Scholar 

  43. Lewis S, Burmeister S, Brazier J. Effect of the prebiotic oligofructose on relapse of Clostridium difficile-associated diarrhea: a randomized, controlled study. Clin Gastroenterol Hepatol. 2005;3(5):442–8.

    Article  PubMed  CAS  Google Scholar 

  44. Heyland DK, Novak F, Drover JW, et al. Should immunonutrition become routine in critically ill patients? A systematic review of the evidence. JAMA. 2001;286(8):944–53.

    Article  PubMed  CAS  Google Scholar 

  45. Marik PE, Zaloga GP. Immunonutrition in critically ill patients: a systematic review and analysis of the literature. Intensive Care Med. 2008;34(11):1980–90.

    Article  PubMed  Google Scholar 

  46. Druml W, Mitch W. Enteral and tube feeding. Philadelphia: WB Saunders; 1997.

    Google Scholar 

  47. Abras E, Walser M. Nitrogen utilization in uremic patients fed by continuous nasogastric infusion. Kidney Int. 1982;22(4):392–7.

    Article  PubMed  CAS  Google Scholar 

  48. Frankfort JD, Fischer CE, Stansbury DW, et al. Effects of high- and low-carbohydrate meals on maximum exercise performance in chronic airflow obstruction. Chest. 1991;100(3):792–5.

    Article  PubMed  CAS  Google Scholar 

  49. Vermeeren MA, Wouters EF, Nelissen LH, et al. Acute effects of different nutritional supplements on symptoms and functional capacity in patients with chronic obstructive pulmonary disease. Am J Clin Nutr. 2001;73(2):295–301.

    PubMed  CAS  Google Scholar 

  50. O’Keefe SJ, Ogden J, Ramjee G, et al. Short-term effects of an intravenous infusion of a nutrient solution containing amino acids, glucose and insulin on leucine turnover and amino acid metabolism in patients with liver failure. J Hepatol. 1988;6(1):101–8.

    Article  PubMed  Google Scholar 

  51. Blackburn GL, O’Keefe SJ. Nutrition in liver failure. Gastroenterology. 1989;97(4):1049–51.

    PubMed  CAS  Google Scholar 

  52. Le Cornu KA, McKiernan FJ, Kapadia SA, et al. A prospective randomized study of preoperative nutritional supplementation in patients awaiting elective orthotopic liver transplantation. Transplantation. 2000;69(7):1364–9.

    Article  PubMed  Google Scholar 

  53. Kearns PJ, Young H, Garcia G, et al. Accelerated improvement of alcoholic liver disease with enteral nutrition. Gastroenterology. 1992;102(1):200–5.

    PubMed  CAS  Google Scholar 

  54. Dasgupta M, Binns MA, Rochon PA. Subcutaneous fluid infusion in a long-term care setting. J Am Geriatr Soc. 2000;48(7):795–9.

    PubMed  CAS  Google Scholar 

  55. Remington R, Hultman T. Hypodermoclysis to treat dehydration: a review of the evidence. J Am Geriatr Soc. 2007;55(12):2051–5.

    Article  PubMed  Google Scholar 

  56. Hearnshaw SA, Thompson NP. Use of parenteral nutrition in hospitals in the North of England. J Hum Nutr Diet. 2007;20(1):14–23; quiz 24–6.

    Google Scholar 

  57. American Gastroenterological Association medical position statement: parenterul nutrition. Gastroenterology. 2001;121(4):966–9.

    Google Scholar 

  58. Anderson AD, Palmer D, MacFie J. Peripheral parenteral nutrition. Br J Surg. 2003;90(9):1048–54.

    Article  PubMed  CAS  Google Scholar 

  59. Howard L, Malone M. Clinical outcome of geriatric patients in the United States receiving home parenteral and enteral nutrition. Am J Clin Nutr. 1997;66(6):1364–70.

    PubMed  CAS  Google Scholar 

  60. O’Keefe SJ, Burnes JU, Thompson RL. Recurrent sepsis in home parenteral nutrition patients: an analysis of risk factors. JPEN J Parenter Enteral Nutr. 1994;18(3):256–63.

    Article  PubMed  Google Scholar 

  61. Burnes JU, O’Keefe SJ, Fleming CR, et al. Home parenteral nutrition—a 3-year analysis of clinical and laboratory monitoring. JPEN J Parenter Enteral Nutr. 1992;16(4):327–32.

    Article  PubMed  CAS  Google Scholar 

  62. Heyland DK, Dhaliwal R, Drover JW, et al. Canadian clinical practice guidelines for nutrition support in mechanically ventilated, critically ill adult patients. JPEN J Parenter Enteral Nutr. 2003;27(5):355–73.

    Article  PubMed  Google Scholar 

  63. Cangelosi MJ, Auerbach HR, Cohen JT. A clinical and economic evaluation of enteral nutrition. Curr Med Res Opin. 2011;27(2):413–22.

    Article  PubMed  Google Scholar 

  64. Hitchings H, Best C, Steed I. Home enteral tube feeding in older people: consideration of the issues. Br J Nurs. 2010;19(18):1150–4.

    PubMed  Google Scholar 

  65. Tkatch L, Rapin CH, Rizzoli R, et al. Benefits of oral protein supplementation in elderly patients with fracture of the proximal femur. J Am Coll Nutr. 1992;11(5):519–25.

    PubMed  CAS  Google Scholar 

  66. Lawson RM, Doshi MK, Barton JR, et al. The effect of unselected post-operative nutritional supplementation on nutritional status and clinical outcome of orthopaedic patients. Clin Nutr. 2003;22(1):39–46.

    Article  PubMed  CAS  Google Scholar 

  67. Stratton RJ, Ek AC, Engfer M, et al. Enteral nutritional support in prevention and treatment of pressure ulcers: a systematic review and meta-analysis. Ageing Res Rev. 2005;4(3):422–50.

    Article  PubMed  Google Scholar 

  68. Wouters-Wesseling W, Van Hooijdonk C, Wagenaar L, et al. The effect of a liquid nutrition supplement on body composition and physical functioning in elderly people. Clin Nutr. 2003;22(4):371–7.

    Article  PubMed  CAS  Google Scholar 

  69. Faxen-Irving G, Andren-Olsson B, af Geijerstam A, et al. The effect of nutritional intervention in elderly subjects residing in group-living for the demented. Eur J Clin Nutr. 2002;56(3):221–7.

    Article  PubMed  CAS  Google Scholar 

  70. Milne AC, Potter J, Avenell A. Protein and energy supplementation in elderly people at risk from malnutrition. Cochrane Database Syst Rev. 2005;(2):CD003288.

    Google Scholar 

  71. Avenell A, Handoll HH. Nutritional supplementation for hip fracture aftercare in older people. Cochrane Database Syst Rev. 2005;(2):CD001880.

    Google Scholar 

  72. Gray-Donald K, Payette H, Boutier V. Randomized clinical trial of nutritional supplementation shows little effect on functional status among free-living frail elderly. J Nutr. 1995;125(12):2965–71.

    PubMed  CAS  Google Scholar 

  73. Wouters-Wesseling W, Wouters AE, Kleijer CN, et al. Study of the effect of a liquid nutrition supplement on the nutritional status of psycho-geriatric nursing home patients. Eur J Clin Nutr. 2002;56(3):245–51.

    Article  PubMed  CAS  Google Scholar 

  74. Espaulella J, Guyer H, Diaz-Escriu F, et al. Nutritional supplementation of elderly hip fracture patients. A randomized, double-blind, placebo-controlled trial. Age Ageing. 2000;29(5):425–31.

    Article  PubMed  CAS  Google Scholar 

  75. Patel PH, Thomas E. Risk factors for pneumonia after percutaneous endoscopic gastrostomy. J Clin Gastroenterol. 1990;12(4):389–92.

    Article  PubMed  CAS  Google Scholar 

  76. Abitbol V, Selinger-Leneman H, Gallais Y, et al. [Percutaneous endoscopic gastrostomy in elderly patients. A prospective study in a geriatric hospital]. Gastroenterol Clin Biol. 2002;26(5):448–53.

    PubMed  Google Scholar 

  77. Norton B, Homer-Ward M, Donnelly MT, et al. A randomised prospective comparison of percutaneous endoscopic gastrostomy and nasogastric tube feeding after acute dysphagic stroke. BMJ. 1996;312(7022):13–6.

    Article  PubMed  CAS  Google Scholar 

  78. Dwolatzky T, Berezovski S, Friedmann R, et al. A prospective comparison of the use of nasogastric and percutaneous endoscopic gastrostomy tubes for long-term enteral feeding in older people. Clin Nutr. 2001;20(6):535–40.

    Article  PubMed  CAS  Google Scholar 

  79. Lee JS, Frongillo Jr EA. Nutritional and health consequences are associated with food insecurity among U.S. elderly persons. J Nutr. 2001;131(5):1503–9.

    PubMed  CAS  Google Scholar 

  80. Shizgal HM, Martin MF, Gimmon Z. The effect of age on the caloric requirement of malnourished individuals. Am J Clin Nutr. 1992;55(4):783–9.

    PubMed  CAS  Google Scholar 

  81. Morley JE. Nutrition in the elderly. Curr Opin Gastroenterol. 2002;18(2):240–5.

    Article  PubMed  CAS  Google Scholar 

  82. Sarkisian S, Fenton TR, Shaheen AA, et al. Parenteral nutrition-associated hyperglycemia in noncritically ill inpatients is associated with higher mortality. Can J Gastroenterol. 2010;24(7):453–7.

    PubMed  Google Scholar 

  83. Matsushima K, Cook A, Tyner T, et al. Parenteral nutrition: a clear and present danger unabated by tight glucose control. Am J Surg. 2010;200(3):386–90.

    Article  PubMed  CAS  Google Scholar 

  84. Allison SP, Lobo DN. Fluid and electrolytes in the elderly. Curr Opin Clin Nutr Metab Care. 2004;7(1):27–33.

    Article  PubMed  Google Scholar 

  85. Kagansky N, Levy S, Koren-Morag N, et al. Hypophosphataemia in old patients is associated with the refeeding syndrome and reduced survival. J Intern Med. 2005;257(5):461–8.

    Article  PubMed  CAS  Google Scholar 

  86. Al-Jaouni R, Schneider SM, Rampal P, et al. Effect of age on substrate oxidation during total parenteral nutrition. Nutrition. 2002;18(1):20–5.

    Article  PubMed  CAS  Google Scholar 

  87. Aberg W, Thorne A, Olivecrona T, et al. Fat oxidation and plasma removal capacity of an intravenous fat emulsion in elderly and young men. Nutrition. 2006;22(7–8):738–43.

    Article  PubMed  Google Scholar 

  88. Walshe C, Phelan D, Bourke J, et al. Vascular erosion by central venous catheters used for total parenteral nutrition. Intensive Care Med. 2007;33(3):534–7.

    Article  PubMed  Google Scholar 

  89. Oz V, Theilla M, Singer P. Eating habits and quality of life of patients receiving home parenteral nutrition in Israel. Clin Nutr. 2008;27(1):95–9.

    Article  PubMed  Google Scholar 

  90. Huerta G, Viniegra L. [Involuntary weight loss as a clinical problem]. Rev Invest Clin. 1989;41(1):5–9.

    PubMed  CAS  Google Scholar 

  91. Bistrian BR, Driscoll DF. Enteral and parenteral nutrition therapy, vol. 17e. New York: McGraw-Hill; 2008.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Manie Juneja MD .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2012 Springer Science+Business Media, LLC

About this chapter

Cite this chapter

Juneja, M., O’Keefe, S.J.D. (2012). Enteral and Parenteral Nutrition. In: Pitchumoni, C., Dharmarajan, T. (eds) Geriatric Gastroenterology. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-1623-5_14

Download citation

  • DOI: https://doi.org/10.1007/978-1-4419-1623-5_14

  • Published:

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4419-1622-8

  • Online ISBN: 978-1-4419-1623-5

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics