Abstract
This chapter on neuroradiology for ophthalmologic tumors discusses the basic utilization of computed tomography and magnetic resonance imaging in the evaluation of lesions involving the globe and orbit. The protocol for these techniques, relevant imaging anatomy, and imaging features of the more common ophthalmologic tumors are discussed. The common radiographic features of ocular lesions, such as retinoblastoma, melanoma, and uveal metastases, as well as orbital lesions, including lymphoma, rhabdomysarcoma, nerve sheath tumors, fibrous lesions, and orbital pseudotumors are discussed. Lesions of the optic nerve, including glioma and meningioma, are also covered. The final section discusses radiographic findings for lesions of the lacrimal gland, secondary spread of tumors to the orbit and periocular region, and cutaneous lesions of the periocular region, including perineural tumor spread.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Gayed I, Eskandari MF, McLaughlin P, et al. Value of positron emission tomography in staging ocular adnexal lymphomas and evaluating their response to therapy. Ophthalmic Surg Lasers Imaging 2007;110:809–15.
Ettl A, Salomonowitz E, Koorneef L, et al. High resolution MR imaging anatomy of the orbit: correlation with comparative cryosectional anatomy. Radiol Clin North Am 1998;36:1021–45.
Francke U. Retinoblastoma and chromosome 13. Cytogenet Cell Genet 1976;16:131–4.
Knudson AG, Meadows AT, Nichols WW, et al. Chromosomal deletion and retinoblastoma. N Engl J Med 1976;295:1120–3.
Kaufman LM, Mafee MF, Song CD. Retinoblastoma and simulating lesion: role of CT, MR imaging, and the use of GD-DTPA contrast enhancement. Radiol Clin North Am 1998;36:1101–17.
Kadom N, Sze RW. Radiological reasoning: leukocoria in a child. AJR Am J Roentgenol 2008;191:40–4.
Devesa SS. The incidence of retinoblastoma. Am J Ophthalmol 1975;80:236–65.
Abramson DH, Ellsworth RM, Tretter P, et al. Treatment of bilateral groups I through III retinoblastoma with bilateral radiation. Arch Ophthalmol 1981;99:1762.
Wycliffe ND, Mafee MF. Magnetic resonance imaging in ocular pathology. Top Magn Reson Imaging 1999;10:384–400.
Apushkin MA, Shapiro MJ, Mafee MF. Retinoblastoma and simulating lesions: role of imaging. Neuroimaging Clin N Am 2005;15:49–67.
Mafee MF, Goldberg MF, Greenwald MJ, et al. Retinoblastoma and simulating lesions: role of CT and MR imaging. Radiol Clin North Am 1987;25:667–81.
Bader JL, Meadows AT, Zimmerman LE, et al. Bilateral retinoblastoma with ectopic intracranial retinoblastoma: trilateral retinoblastoma. Cancer Genet Cytogenet 1982;5:203–13.
Bader JL, Miller RW, Meadows AT, et al. Trilateral retinoblastoma. Lancet 1980;2:582–3.
Demirci H, Shields CL, Karatza EC, et al. Orbital lymphoproliferative tumors: analysis of clinical features and systemic involvement in 160 cases. Ophthalmology 2008;115:1626–31.
Hatef E, Roberts D, McLaughlin P, et al. Prevalence and nature of systemic involvement and stage at initial examination in patients with orbital and ocular adnexal lymphoma. Arch Ophthalmol 2007;125:1663–7.
Valvassori GE, Sabnis SS, Mafee RF, et al. Imaging of orbital lymphoproliferative disorders. Radiol Clin North Am 1999;37:135–50.
Zacharia TT, Law M, Naidich TP, et al. Central nervous system lymphoma characterization by diffusion-weighted imaging and MR spectroscopy. J Neuroimaging 2008;18:411–17.
Sohaib SA, Moseley I, Wright JE. Orbital rhabdomyosarcoma: the radiological characteristics. Clin Radiol 1998;53:357–62.
Shields JA, Shields CL. Rhabdomyosarcoma: review for the ophthalmologist. Ophthalmology 2003;48:39–57.
Folpe AL, McKenney JK, Bridge JA, et al. Sclerosing rhabdomyosarcoma in adults: report of four cases of hyalinizing, matrix-rich variant of rhabdomyosarcoma that may be confused with osteosarcoma, chondrosarcoma, or angiosarcoma. Am J Surg Pathol 2002;26:1175–83.
Albert DM, Jakobiec FA. Principles and Practice of Ophthalmology, second edition. Philadelphia, PA: WB Saunders, 2000.
DePotter P, Shields JA, Shields CL. MRI of the Eye and Orbit. Philadelphia, PA: JB Lippincott, 1995.
Font RL, Hidayat AA. Fibrous histiocytoma of the orbit: a clinicopathologic study of 150 cases. Hum Pathol 1982;13:199.
Ros PR, Kursunoglu S, Batle JF, et al. Malignant fibrous histiocytoma of the orbit. J Clin Neuroophthalmol 1985;5:116.
Dalley R. Fibrous histiocytoma and fibrous tissue tumors of the orbit. Radiol Clin North Am 1999;37:185–94.
Shields JA. Diagnosis and Management of Orbital Tumors. Philadelphia, PA: WB Saunders, 1989.
Krishnakumar S, Subramanian N, Mohan ER, et al. Solitary fibrous tumor of the orbit: a clinicopathologic study of six cases with review of the literature. Surv Ophthalmol 2003;48:544–54.
Eggers H, Jakobiec FA, Jones IS. Optic nerve gliomas. In: Jones IS, Jakobiec FA, editors. Diseases of the Orbit. New York, NY: Harper & Row, 1979:417–33.
Dutton JJ. Gliomas of the anterior visual pathways. Surv Ophthalmol 1994;384:27–52.
Parsa CF, Hoyt CS, Lesser RL, et al. Spontaneous regression of optic gliomas: thirteen cases documented by serial neuroimaging. Arch Ophthalmol 2001;119:516–29.
Weber AL, Klufas R, Pless M. Imaging evaluation of the optic nerve and visual pathway including cranial nerves affecting the visual pathway. Neuroimaging Clin N Am 1996;6:143–77.
Mehra KS, Khanna S, Dube B. Primary meningiomas of the intraorbital optic nerve. Ann Ophthalmol 1979;11:758–60.
Dutton JJ. Optic nerve sheath meningiomas. Surv Ophthalmol 1992;37:167–83.
Hecht SD. Dacryocystorhinostomy. In: Hornblas A, Hanig CJ, editors. Oculoplastic, Orbital, and Reconstructive Surgery. Baltimore, MD: Williams & Wilkins, 1990:1433–40.
Jakobiec FA, Yeo JH, Trokel SL, et al. Combined clinical and computed tomographic diagnosis or primary lacrimal fossa lesions. Am J Ophthalmol 1982;94:785–807.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2010 Springer Science+Business Media, LLC
About this chapter
Cite this chapter
Debnam, J.M. (2010). Neuroradiology of Ocular and Orbital Tumors. In: Esmaeli, B. (eds) Ophthalmic Oncology. M.D. Anderson Solid Tumor Oncology Series, vol 6. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-0374-7_12
Download citation
DOI: https://doi.org/10.1007/978-1-4419-0374-7_12
Published:
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4419-0373-0
Online ISBN: 978-1-4419-0374-7
eBook Packages: MedicineMedicine (R0)