Abstract
In aging studies, resilience is often used to suggest an ability to recover from stressors and the relative degree of resilience depends on the stressor in question. Individuals may have adequate physiologic reserves to recover from moderate stressors yet lack sufficient resilience to recover from severe stressors. We have examined the recovery process from the relatively significant physiologic stressor of hip fracture. Following a hip fracture, there is a sudden loss of physical function (as measured by ability to walk independently and walking speed) followed by a period of recovery that can continue for a year or more depending on the area of function examined. The trauma of hip fracture and subsequent surgical repair may result in an oxidative stress and inflammatory response that, if excessive, can result in a detrimental effect on muscle strength and function. Antioxidant vitamins, vitamin D, and the statin class of medications and exercise may exert a beneficial effect, in part through a favorable modification of the post-traumatic inflammatory response.
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Hicks, G., Miller, R.R. (2011). Physiological Resilience. In: Resnick, B., Gwyther, L., Roberto, K. (eds) Resilience in Aging. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-0232-0_6
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