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The Cytoskeleton of the Living Cell as an Out-of-Equilibrium System

  • Chapter
Phase Transitions in Cell Biology

Abstract

In a remarkably broad range of eukaryotic cell types, the cytoskeleton exhibits physical properties and remodelling dynamics strongly reminiscent of soft inert condensed systems, although with important differences as well. This unexpected intersection of condensed matter physics and cytoskeletal biology suggests that trapping, intermittency, and approach to kinetic arrest represent central mesoscale features linking underlying molecular events to integrative cellular functions such as crawling, contraction and remodelling.

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Authors and Affiliations

  1. Molecular and Integrative Physiological Sciences, Department of Environmental Health, Harvard School of Public Health, Boston, MA, USA

    Guillaume Lenormand, Adriano M. Alencar, Xavier Trepat, En-hua Zhou, Ben Fabry, James P. Butler & Jeffrey J. Fredberg

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  1. Guillaume Lenormand
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Editors and Affiliations

  1. Department of Bioengineering, University of Washington, Box 355061, Seattle, WA 98195, USA

    Gerald H. Pollack

  2. PO Box 2039, Merced, CA 95344, USA

    Wei-Chun Chin

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© 2008 Springer Science+Business Media B.V.

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Lenormand, G. et al. (2008). The Cytoskeleton of the Living Cell as an Out-of-Equilibrium System. In: Pollack, G.H., Chin, WC. (eds) Phase Transitions in Cell Biology. Springer, Dordrecht. https://doi.org/10.1007/978-1-4020-8651-9_8

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