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Risk Factors

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Breast Cancer Risk Reduction and Early Detection

Abstract

Important improvements have occurred in the past several years in our understanding of the causes and prevention of breast cancer. Age, family history of breast cancer, and experiences of reproductive life have long been known to be associated with breast cancer risk. More recently, new factors have emerged, including obesity, low physical activity, alcohol intake, and exogenous hormone use. Of these new factors, many appear to be related to perturbations in circulating estrogens, which are believed to be the major cause of breast cancer. Although there is a high level of interest in environmental causes of breast cancer, very few common exposures have proved to be associated with the disease. Although some of the factors that increase risk are not amenable to change, many are meaningfully modifiable, even when change is undertaken later in life.

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Authors and Affiliations

  1. Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA

    Polly A. Newcomb

  2. Department of Epidemiology, School of Public Health, University of Washington, Seattle, USA

    Polly A. Newcomb

  3. Paul P. Carbone Comprehensive Cancer Center, University of Washington, Seattle, USA

    Polly A. Newcomb

  4. Fred Hutchinson Cancer Research Center, 98109, Seattle, WA, USA

    Polly A. Newcomb & Karen J. Wernli

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  1. Polly A. Newcomb
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  2. Karen J. Wernli
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Correspondence to Polly A. Newcomb .

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  1. School of Medicine & Health Sciences, University of North Dakota, N. Columbia Road 501, Grand Forks, 58203, U.S.A.

    Edward R. Sauter

  2. Dept. Medical Oncology, Fox Chase Cancer Center, Cottman Ave. 333, Philadelphia, 19111-2497, U.S.A.

    Mary B. Daly

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Newcomb, P.A., Wernli, K.J. (2010). Risk Factors. In: Sauter, E., Daly, M. (eds) Breast Cancer Risk Reduction and Early Detection. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-87583-5_1

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