Abstract
In this chapter, we briefly outline the basic preliminary information about the heart as a pump in the blood circulatory system, its structure, and major component systems. The material presented here is a series of short excerpts from A.C. Guyton and J.E. Hall’s “Textbook of Medical Physiology” [1], which is meant to introduce readers without biological background to the basic terminology, definitions and functions of the heart systems as part of the whole organ. We will look at additional physiological information in greater depth in later chapters.
Here we also emphasize that heart arrhythmias and fibrillation continue to be dangerous heart diseases, the mechanisms of which have not been clearly understood until recently. Mathematical modeling and computer simulations are characterized as modern tools for scientific research in this area.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Guyton, A.C. and J.E. Hall, Textbook of Medical Physiology. 9th ed. 1996, Philadelphia: W.B. Saunders.
Hoffman, B.F. and P.F. Cranefield, Electrophysiology of the Heart. 1960, New York: McGraw-Hill.
Zipes, D. and J. Jalife, eds. Cardiac Electrophysiology: From Cell to Bedside. 2nd ed. 1995, W.B. Saunders: Philadelphia.
Weiss, J.N., Transition of Sinus Rhythm to VT to VF, Unpublished.
Rajskina, M.E., Ventricular Fibrillation and Sudden Coronary Death. 1999: Kluwer Academic Publishers.
Bers, D.M., Excitation-Contraction Coupling and Cardiac Contractile Force. 2nd ed. 2001, Norwell, MA: Kluwer Academic Publishers.
Garfinkel, A., ChenP.-S., WalterD.O., KaragueuzianH.S., KoganB., EvansS.J., KarpoukhinM., HwangC., UchidaT., GotohM., NwasokwaO., SagerP., and WeissJ.NQuasiperiodicity and chaos in cardiac fibrillation. J Clin Invest, 1997. 99: 305–314.
Davidenko, J.M., A.V. Pertsov, J.R. Salomonsz, W.Baxter, and JalifeJ., Stationary and drifting spiral waves of excitation in isolated cardiac muscle. Nature, 1992. 355: 349–351.
Keener, J. and J. Sneyd, Mathematical Physiology. 2nd ed. 2001: Springer-Verlag.
Bassingthwaighte, J.B., Toward modeling the human physiome. Adv Exp Med Biol, 1999. 382: 331–339.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
Copyright information
© 2010 Springer Science+Business Media, LLC
About this chapter
Cite this chapter
Kogan, B.J. (2010). Introduction. In: Introduction to Computational Cardiology. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-76686-7_1
Download citation
DOI: https://doi.org/10.1007/978-0-387-76686-7_1
Published:
Publisher Name: Springer, Boston, MA
Print ISBN: 978-0-387-76685-0
Online ISBN: 978-0-387-76686-7
eBook Packages: Computer ScienceComputer Science (R0)