Skip to main content
SpringerLink
Log in

Pharmaceutical formulations of nimesulide

  • Chapter
Nimesulide — Actions and Uses

  • 658 Accesses

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Güngör S, Bergisşadi N (2004) Effect of penetration enhancers on in vitro percutaneous penetration of nimesulide through rat skin. Pharmazie 59(1): 39–41

    PubMed  Google Scholar 

  2. Shahiwala A, Misra A (2002) Studies in topical application of niosomally entrapped nimesulide. J Pharm Pharmaceut Sci 5(3): 220–225

    CAS  Google Scholar 

  3. Ceschel GC, Maffei P, Lombardi Borgia S (2001) Design and evaluation of a new mucoadhesive bi-layered tablet containing nimesulide for buccal administration. S.T.P. Pharma Sci 11(2): 151–156

    CAS  Google Scholar 

  4. Maffei P, Lombardi Borgia S, Sforzini A, Bergamante V, Ceschel GC, Fini A, Ronchi C (2004) Mucoadhesive tablets for buccal administration containing sodium nimesulide. Drug Del 11(4): 225–230

    Article  CAS  Google Scholar 

  5. Agrawal S, Pancholi SS, Jain NK, Agrawal GP (2004) Hydrotropic solubilization of nimesulide for parenteral administration. Int J Pharm 274: 149–155

    Article  PubMed  CAS  Google Scholar 

  6. Vandelli MA, Ruozi B, Forni F (1999) PLA microparticles for the prolonged release of nimesulide: effect of preparative variables. S.T.P. Pharma Sci 9(61): 567–572

    CAS  Google Scholar 

  7. Amidon GL, Lennernas H, Shah VP, Crison JR (1995) A theoretical basis for a biopharmaceutic drug classification: The correlation of in vitro drug product dissolution and in vivo bioavailability. Pharm Res 12(3): 413–420

    Article  PubMed  CAS  Google Scholar 

  8. Miro A, Quaglia F, Calignano A, Barbato F, Cappello B, La Rotonda MI (2000) Physicochemical and pharmacological properties of nimesulide/beta-cyclodextrin formulations. S.T.P. Pharma Sci 10(2): 157–164

    CAS  Google Scholar 

  9. Thompson DO (1997) Cyclodextrins — Enabling excipients: Their present and future use in pharmaceuticals. Crit Rev Ther Drug Carrier Syst 14(1): 1–104

    PubMed  CAS  Google Scholar 

  10. Vizzardi M, Sagarriga Visconti C, Pedrotti L, Marzano N, Berruto M, Scotti A (1998) Nimesulide beta cyclodextrin (nimesulide-betadex) versus nimesulide in the treatment of pain after arthroscopic surgery. Curr Ther Res Clin Exp 59(3): 162–171

    Article  CAS  Google Scholar 

  11. Chowdary KPR, Nalluri BN (2000) Nimesulide and beta-cyclodextrin inclusion complexes: Physicochemical characterization and dissolution rate studies. Drug Dev Ind Pharm 26(11): 1217–1220

    PubMed  CAS  Google Scholar 

  12. Adhage NA, Vavia PR (2000) Beta cyclodextrin inclusion complexation by milling. Pharm Pharmacol Commun 6(1): 13–17

    CAS  Google Scholar 

  13. Moneghini M, Kikic I, Perissutti B, Franceschinis E, Cortesi A (2004) Characterisation of nimesulide-betacyclodextrins systems prepared by supercritical fluid impregnation. Eur J Pharm Biopharm 58(3): 637–644

    PubMed  CAS  Google Scholar 

  14. Vavia PR, Adhage NA (1999) Inclusion complexation of nimesulide with beta-cyclodextrins. Drug Dev Ind Pharm 25(4): 543–545

    Article  PubMed  CAS  Google Scholar 

  15. Piel G, Pirotte B, Delneuville I, Neven P, Llabres G, Delarge J, Delattre L (1997) Study of the influence of both cyclodextrins and L-lysine on the aqueous solubility of nimesulide; Isolation and characterization of nimesulide-L-lysine-cyclodextrin complexes. J Pharm Sci 86(4): 475–480

    Article  PubMed  CAS  Google Scholar 

  16. Nalluri BN, Chowdary KR, Murthy KR, Hayman AR, Becket G (2003) Physicochemical characterization and dissolution properties of nimesulide-cyclodextrin binary systems. AAPS PharmSciTech 4(1): article 2

    Google Scholar 

  17. Gohel MC, Patel LD (2000) Improvement of nimesulide dissolution by a co-grinding method using surfactants. Pharm Pharmacol Commun 6(10): 433–440

    CAS  Google Scholar 

  18. Meriani F, Coceani N, Sirotti C, Voinovich D, Grassi M (2003) Characterization of a quaternary liquid system improving the bioavailability of poorly water soluble drugs. J Colloid Interface Sci 263(2): 590–596

    Article  PubMed  CAS  Google Scholar 

  19. Meriani F, Coceani N, Sirotti C, Voinovich D, Grassi M (2004) In vitro nimesulide absorption from different formulations. J Pharm Sci 93(3): 540–552

    Article  PubMed  CAS  Google Scholar 

  20. Gohel MC, Patel LD (2002) Improvement of nimesulide dissolution from solid dispersions containing croscaramellose sodium and Aerosil 200. Acta Pharm 52(4): 227–241

    CAS  Google Scholar 

  21. Gohel MC, Patel LD (2003) Processing of nimesulide-PEG400-PG-PVP solid dispersions: Preparation, characterization, and in vitro dissolution. Drug Dev Ind Pharm 29(3): 299–310

    PubMed  CAS  Google Scholar 

  22. Murali Mohan Babu GV, Ravi Kumar N, Himasankar K, Seshasayana A, Ramana Murthy KV (2003) Nimesulide-modified gum karaya solid mixtures: Preparation, characterization, and formulation development. Drug Dev Ind Pharm 29(8): 855–864

    Article  CAS  Google Scholar 

  23. Gohel MC, Patel M, Amin A, Agrawal R, Dave R, Bariya N (2004) Formulation design and optimization of mouth dissolve tablets of nimesulide using vacuum drying technique. AAPS PharmSciTech 5(3): article 36

    Google Scholar 

  24. Madhuri K, Prasnthi E, Manasa, Durvasa Rao B, Goureenadh N, Chowdary YA, Murthy TEGK (2004) Design and in vitro evaluation of nimesulide controlled release tablets. Pharma Rev 2(9): 107–108

    CAS  Google Scholar 

  25. Verma RK, Mishra B (1999) Studies on formulation and evaluation of oral osmotic pumps of nimesulide. Pharmazie 54(1): 74–75

    CAS  Google Scholar 

  26. WHO (World Health Organization) (1993) Interchangeable multi-source pharmaceutical products. WHO draft guideline on marketing authorization requirements

    Google Scholar 

  27. A.F.I. Working Party (1996) Generici, aspetti regolatori e tecnici. Acta Technol Legis Med VII(1): 1–29

    Google Scholar 

  28. Butler D, Bonadeo D, Maroni A, Foppoli A, Zema L, Giordano F (2000) Comparative in vitro evaluation of nimesulide-containing preparations on the Italian market. Boll Chim Farm 139(6): 237–241

    PubMed  CAS  Google Scholar 

  29. Hutt V, Waitzinger J, Macchi F (2001) Comparative bioavailability study of two different nimesulide-containing preparations available on the Italian market. Clin Drug Invest 21(5): 361–369

    CAS  Google Scholar 

  30. Hutt V, Waitzinger J (2001) Generics, copies and original drugs: Are they really interchangeable? Investigations on nimesulide-containing preparations. J Clin Res 4: 77–89

    Google Scholar 

  31. Ministero della Salute (2003) Revoca, su rinuncia, dell’autorizzazione all’immissione in commercio della specialità medicinale per uso umano “Nimesulide”. Gazzetta Ufficiale della Repubblica Italiana 95: 90

    Google Scholar 

  32. Ministero della Salute (2003) Revoca, su rinuncia, dell’autorizzazione all’immissione in commercio della specialità medicinale per uso umano “Sulidamor”. Gazzetta Ufficiale della Repubblica Italiana 59: 52

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Istituto di Chimica Farmaceutica e Tossicologica, Università degli Studi di Milano, Viale Abruzzi 42, 20131, Milano, Italy

    A. Maroni & A. Gazzaniga

Authors
  1. A. Maroni
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. A. Gazzaniga
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Biomedical Research Centre, Sheffield Hallam University, Howard Street, Sheffield, S1 1WB, UK

    K.D. Rainsford

Rights and permissions

Reprints and permissions

Copyright information

© 2005 Birkäuser Verlag Basel/Switzerland

About this chapter

Cite this chapter

Maroni, A., Gazzaniga, A. (2005). Pharmaceutical formulations of nimesulide. In: Rainsford, K. (eds) Nimesulide — Actions and Uses. Birkhäuser Basel. https://doi.org/10.1007/3-7643-7410-1_3

Download citation

Publish with us

Policies and ethics

Search

Navigation