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References
Hartman, S.C.; Buchanan, J.M.: Biosynthesis of the purines. XXVI. The identification of the formyl donors of the transformylation reactions. J. Biol. Chem., 234, 1812–1816 (1959)
Patrick, T.W.; Crosbie, G.W.: Specificity of 4-aminoimidazole-5-carbox-amide ribotide transformylase of Escherichia coli. Biochem. J., 124, 31–32 (1971)
Iwai, K.; Fujisawa, Y.; Suzuki, N.: The accumulation of 5’-phosphoribosyl-5-amino-4-imidazolecarboxamide in folate-deficient pea seedlings and the enzymatic reaction in which the compound is involved. Agric. Biol. Chem., 36, 398–408 (1972)
Baggott, J.E.; Krumdieck, C.L.: Folylpoly-y-glutamates as cosubstrates of 10-formyltetrahydrofolate:5’-phosphoribosyl-5-amino-4-imidazole-carbox-amide formyltransferase. Biochemistry, 18, 1037–1041 (1979)
Mueller, W.T.; Benkovic, S.J.: On the purification and mechanism of action of 5-aminoimidazole-4-carboxamide-ribonucleotide transformylase from chicken liver. Biochemistry, 20, 337–344 (1981)
Smith, G.K.; Mueller, T.; Benkovic, P.A.; Benkovic, S.J.: On the cofactor specificity of glycinamide ribonucleotide and 5-aminoimidazole-4-carbox-amide ribonucleotide transformylase from chicken liver. Biochemistry, 20, 1241–1245 (1981)
Baggott, J.E.; Vaughn, W.H.; Hudson, B.B.: Inhibition of 5-aminoimidazole-4-carboxamide ribotide transformylase, adenosine deaminase and 5’-adenylate deaminase by polyglutamates of methotrexate and oxidized folates and by 5-aminoimidazole-4-carboxamide riboside and ribotide. Biochem. J., 236, 193–200 (1986)
Ha, T.; Morgan, S.L.; Vaughn, W.H; Eto, I.; Baggott, J.E.: Detection of inhibition of 5-aminoimidazole-4-carboxamide ribotide transformylase by thioinosinic acid and azathioprine by a new colorimetric assay. Biochem. J., 272, 339–342 (1990)
Szabados, E.; Hindmarsh, E.J.; Phillips, L.; Duggleby, R.G.; Christopherson, R.I.: 5-Aminoimidazole-4-carboxamide ribotide transformylase-IMP cyclo-hydrolase from human CCRF-CEM leukemia cells: purification, pH dependence and inhibitors. Biochemistry, 33, 14237–14245 (1994)
Rayl, E.A.; Moroson, B.A.; Beardsley, G.P.: The human purH gene product, 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. Cloning, sequencing, expression, purification, kinetic analysis, and domain mapping. J. Biol. Chem., 271, 2225–2233 (1996)
Boger, D.L.; Haynes, N.E.; Warren, M.S.; Gooljarsingh, L.T.; Ramcharan, J.; Kitos, P.A.; Benkovic, S.J.: Functionalized analogues of 5,8,10-trideazafolate as potential inhibitors of GAR Tfase or AICAR Tfase. Bioorg. Med. Chem., 5, 1831–1838 (1997)
Sugita, T.; Aya, H.; Ueno, M.; Ishizuka, T.; Kawashima, K.: Characterization of molecularly cloned human 5-aminoimidazole-4-carboxamide ribonucleotide transformylase. J. Biochem., 122, 309–313 (1997)
Reyes, V.M.; Greasley, S.E.; Stura, E.A.; Beardsley, G.P.; Wilson, I.A.: Crystallization and preliminary crystallographic investigations of avian 5-amino-imidazole-4-carboxamide ribonucleotide transformylase-inosine mono-phosphate cyclohydrolase expressed in Escherichia coli. Acta Crystallogr. Sect. D, 56, 1051–1054 (2000)
Wall, M.; Shim, J.H.; Benkovic, S.J.: Human AICAR transformylase: Role of the 4-Carboxamide of AICAR in binding and catalysis. Biochemistry, 39, 11303–11311 (2000)
Shim, J.H.; Wall, M.; Benkovic, S.J.; Diaz, N.; Suarez, D.; Merz, K.M., Jr.: Evaluation of the catalytic mechanism of AICAR transformylase by pH-de-pendent kinetics, mutagenesis, and quantum chemical calculations. J. Am. Chem. Soc, 123, 4687–4696 (2001)
Vergis, J.M.; Bulock, K.G.; Fleming, K.G.; Beardsley, G.P.: Human 5-amino-imidazole-4-carboxamide ribonucleotide transformylase/inosine 5’-mono-phosphate cyclohydrolase. A bifunctional protein requiring dimerization for transformylase activity but not for cyclohydrolase activity. J. Biol. Chem., 276, 7727–7733 (2001)
Bulock, K.G.; Beardsley, G.P.; Anderson, K.S.: The kinetic mechanism of the human bifunctional enzyme ATIC (5-amino-4-imidazolecarboxamide ribo-nucleotide transformylase/inosine 5’-monophosphate cyclohydrolase): A surprising lack of substrate channeling. J. Biol. Chem., 277, 22168–22174 (2002)
Wolan, D.W.; Greasley, S.E.; Beardsley, G.R.; Wilson, I.A.: Structural insights into the avian AICAR transformylase mechanism. Biochemistry, 41, 15505–15513 (2002)
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(2006). Phosphoribosylaminoimidazolecarboxamide formyltransferase. In: Schomburg, D., Schomburg, I., Chang, A. (eds) Springer Handbook of Enzymes. Springer Handbook of Enzymes, vol 29. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-37716-6_3
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DOI: https://doi.org/10.1007/3-540-37716-6_3
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