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References
Hope CS, Laurie J et al. (1967) Optimization of X-ray treatment planning by computer judgement. Phys Med Biol 12(4):531–542
Bahr GK, Kereiakes JG et al. (1968) The method of linear programming applied to radiation treatment planning. Radiology 91(4):686–693
Hodes L (1974) Semiautomatic optimization of external beam radiation treatment planning. Radiology 110(1):191–196
McDonald SC, Rubin P (1977) Optimization of external beam radiation therapy. Int J Radiat Oncol Biol Phys 2(3/4):307–317
Starkschall G (1984) A constrained least-squares optimization method for external beam radiation therapy treatment planning. Med Phys 11(5):659–665
Powlis WD, Altschuler MD et al. (1989) Semi-automated radiotherapy treatment planning with a mathematical model to satisfy treatment goals. Int J Radiat Oncol Biol Phys 16(1):271–276
Morrill SM, Lane RG et al. (1991) Treatment planning optimization using constrained simulated annealing. Phys Med Biol 36(10):1341–1361
Lyman JT (1985) Complication probability as assessed from dose-volume histograms. Radiat Res Suppl 8(9):S13–S19
Lyman JT, Wolbarst AB (1987) Optimization of radiation therapy, III: A method of assessing complication probabilities from dose-volume histograms. Int J Radiat Oncol Biol Phys 13(1):103–109
Kutcher GJ, Burman C (1989) Calculation of complication probability factors for non-uniform normal tissue irradiation: the effective volumemethod [see comments]. Int J Radiat Oncol Biol Phys 16(6):1623–1630
Lyman JT, Wolbarst AB (1989) Optimization of radiation therapy, IV: A dose-volume histogram reduction algorithm. Int J Radiat Oncol Biol Phys 17(2):433–436
Niemierko A, Goitein M (1991) Calculation of normal tissue complication probability and dose-volume histogram reduction schemes for tissues with a critical element architecture. Radiother Oncol 20(3):166–176
Kallman P, Agren A et al. (1992) Tumour and normal tissue responses to fractionated non-uniform dose delivery. Int J Radiat Biol 62(2):249–262
Lyman JT (1992) Normal tissue complication probabilities: variable dose per fraction. Int J Radiat Oncol Biol Phys 22(2):247–250
Mohan R, Mageras GS et al. (1992) Clinically relevant optimization of 3-D conformal treatments. Med Phys 19(4):933–944
Niemierko A, Urie M et al. (1992) Optimization of 3D radiation therapy with both physical and biological end points and constraints. Int J Radiat Oncol Biol Phys 23(1):99–108
Niemierko A, Goitein M (1993) Implementation of a model for estimating tumor control probability for an inhomogeneously irradiated tumor. Radiother Oncol 29(2):140–147
Niemierko A, Goitein M (1993) Modeling of normal tissue response to radiation: the critical volume model. Int J Radiat Oncol Biol Phys 25(1):135–145
Webb S (1993) The effect on tumour control probability of varying the setting of a multileaf collimator with respect to the planning target volume. Phys Med Biol 38(12):1923–1936
Mohan R, Wang X et al. (1994) The potential and limitations of the inverse radiotherapy technique. Radiother Oncol 32(3):232–248
Wang XH, Mohan R et al. (1995) Optimization of intensity-modulated 3D conformal treatment plans based on biological indices [see comments]. Radiother Oncol 37(2):140–152
Kutcher GJ (1996) Quantitative plan evaluation: TCP/NTCP models. Frontiers Radiat Ther Oncol 29:67–80
Mohan R, Wang X et al. (1996) Optimization of 3-D conformal radiation treatment plans. Front Radiat Ther Oncol 29:86–103
Niemierko A (1997) Reporting and analyzing dose distributions: a concept of equivalent uniform dose. Med Phys 24(1):103–110
Niemierko A (1998) Radiobiological models of tissue response to radiation in treatment planning systems. Tumori 84(2):140–143
Kutcher G (1990) Quantitative plan evaluation. AAPM Summer School. American Institute of Physics, J Purdy, Woodbury, NY
Wu Q, Mohan R et al. (2002) Optimization of intensity-modulated radiotherapy plans based on the equivalent uniform dose. Int J Radiat Oncol Biol Phys 52(1):224–235
Douglas BG, Fowler JF (1976) The effect of multiple small doses of X rays on skin reactions in the mouse and a basic interpretation. Radiat Res 66(2):401–426
Thames HD (1985) An ‘incomplete-repair’ model for survival after fractionated and continuous irradiations. Int J Radiat Biol 47(3):319–339
Thames HD, Hendry JH (1987) Fractionation in radiotherapy. Taylor & Francis
Hall EJ (1994) Radiobiology for the radiologist. J.B. Lippincott, Philadelphia
Brenner DJ, Hlatky LR et al. (1995) A convenient extension of the linear-quadratic model to include redistribution and reoxygenation. Int J Radiat Oncol Biol Phys 32(2):379–390
Withers HR, Taylor JM et al. (1988) Treatment volume and tissue tolerance. Int J Radiat Oncol Biol Phys 14(4):751–759
Withers HR (1986) Predicting late normal tissue responses. Int J Radiat Oncol Biol Phys 12(4):693–698
Brahme A (1984) Dosimetric precision requirements in radiation therapy. Acta Radiol Oncol 23(5):379–391
Brenner DJ (1993) Dose, volume, and tumor-control predictions in radiotherapy. Int J Radiat Oncol Biol Phys 26(1):171–179
Okunieff P, Morgan D et al. (1995) Radiation dose-response of human tumors. Int J Radiat Oncol Biol Phys 32(4):1227–1237
Terahara A, Niemierko A et al. (1999) Analysis of the relationship between tumor dose inhomogeneity and local control in patients with skull base chordoma. Int J RadiatOncol Biol Phys 45(2):351–358
Goitein M (1985) Calculation of the uncertainty in the dose delivered during radiation therapy. Med Phys 12(5):608–612
Zagars GK, Schultheiss TE et al. (1987) Inter-tumor heterogeneity and radiation dose-control curves. Radiother Oncol 8(4):353–361
Graffman S, Groth T et al. (1975) Cell kinetic approach to optimising dose distribution in radiation therapy. Acta Radiol Ther Phys Biol 14(1):54–62
Fisher ER, Fisher B (1969) Effects of X-irradiation on parameters of tumor growth, histology, and ultrastructure. Cancer 24(1):39–55
Jackson A, Kutcher GJ et al. (1993) Probability of radiation-induced complications for normal tissues with parallel architecture subject to non-uniform irradiation. Med Phys 20(3):613–625
Stavreva N, Niemierko A et al. (2001) Modelling the dose-volume response of the spinal cord, based on the idea of damage to contiguous functional subunits. Int J Radiat Biol 77(6):695–702
Schultheiss TE, Orton CG et al. (1983) Models in radiotherapy: volume effects. Med Phys 10(4):410–415
Jackson A, Ten Haken RK et al. (1995) Analysis of clinical complication data for radiation hepatitis using a parallel architecture model. Int J Radiat Oncol Biol Phys 31(4):883–891
Hartford AC, Niemierko A et al. (1996) Conformal irradiation of the prostate: estimating long-term rectal bleeding risk using dose-volume histograms. Int J Radiat Oncol Biol Phys 36(3):721–730
Herbert ED (ed) (1993) Quality assessment and improvement of dose-responsemodels: some effects of study weaknesses on study findings. “c’est magnifique?” A report of Task Group 1 of the AAPM Biological Effects Committee. AAPM Report No. 43, Med Phys Pub, Madison
Lindsey JK (1997) Applying generalized linear models. Springer, Berlin Heidelberg New York
Burman C, Kutcher GJ et al. (1991) Fitting of normal tissue tolerance data to an analytic function. Int J Radiat Oncol Biol Phys 21(1):123–135
Emami B, Lyman J et al. (1991) Tolerance of normal tissue to therapeutic irradiation. Int J Radiat Oncol Biol Phys 21(1):109–122
Mohan R, Niemierko A (2002). Intensity modulated radiation therapy. ASTRO Syllabus, New Orleans
Kutcher GJ et al. (1991) Histogram reduction method for calculating complication probabilities for three-dimensional treatment planning evaluations. Int J Radiat Oncol Biol, Phys 21(1):137–146
Brahme A (1996) Recent developments in radiation therapy planning and treatment optimization. Australas Phys Eng Sci Med 19(2):53–66
Barendsen GW (1982) Dose fractionation, dose rate and isoeffect relationships for normal tissue responses. Int J Radiat Oncol Biol Phys 8(11):1981–1997
Niemierko A (1999) A generalized concept of Equivalent Uniform Dose. Proceedings of the 41th AAPM Annual Meeting, Nashville, Tennessee. Med Phys 26(6):1100
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Niemierko, A. (2006). Biological Optimization. In: Bortfeld, T., Schmidt-Ullrich, R., De Neve, W., Wazer, D.E. (eds) Image-Guided IMRT. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-30356-1_16
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DOI: https://doi.org/10.1007/3-540-30356-1_16
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