Summary
For disc herniations the use of open surgical approaches is reduced since new percutaneous methods allowing shrinkage of the disc and improvement of the radicular function are gaining interest. Studies on the spontaneous disappearance of disc fragments have demonstrated autoimmune responses with a chronic inflammatory reaction. Also radicular pain has been shown to be mostly due to biochemical mechanisms [10]. Researchers in different fields surprisingly noticed that a brief, calculated, oxidative stress by ozone administration may correct a persistent imbalance due to excessive, chronic oxidative injury [4]. Oxygen-ozone gas injection in painful patients has a dramatic effect on clinical symptoms. On these bases the intradiscal injection of oxygen-ozone gas has been conceived [1, 7, 9]. We report the treatment on a series of patients affected by cervical disc pathology, treated by intradiscal injection of oxygen-ozone gas mixture. The effects both on pain and on radicular dysfunction are impressive. The morphological effect of the treatment was also evaluated by pathological examination.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Alexandre A (1996) Protocollo al Ministero per l’iniezione intradiscale di Ozono Medicale. Roma, Ottobre 1996: 1o Congresso Italiano sull’applicazione dell’Ozono nel trattamento delle ernie discali
Alexandre A, Soattin GB, Fumo G (1997) Intradiscal ozone injection: a new solution for herniated disc problems. Miami Cedars University Course for Neurosurgery, Miami July 27
Alexandre A, Fumo G (1998) Discolisi percutanea mediante 0203 nell’ernia discale lombare. In: Ceccherelli F, Ricciardi A (eds). Lombalgie e lombosciatalgie. Criteri di diagnosis e cura. Edizioni Libreria Cortina, Torino, pp 367–377
Bocci V (1999) Biological and clinical effects of ozone. Has ozone therapy a future in medicine? Br J Biomed Sci 56:270–279
Donato G, Amorosi A, Lavano A et al (2000) Pathologic examination of the lumbar intervertebral disc. An appraisal about utility and limits. Pathologica 92: 327–330
Fandino Rivera J (2000) DesapariciĂ²n espontanea de la hernia discal. Neurocirugia 11: 419–424
Fabris G, Tommasini G, Lavaroni A et al (1997) Percutaneous treatment of lumbar herniated disk. Riv. Neuroradiol 10: 523–532
Jacobs MT (1982) Untersuchung fiber Zwischenfalle und typi sche Komplikationen in der Ozon-Sauerstoff-Therapie. Ozonachrichte: 1–5
Jucopilla N (1995) Personal communication
Saal J, Saal JS, Herzog R (1990) The natural history of the lumbar intervertebral disc extrusion treated nonoperatively. Spine 15: 683–686
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2005 Springer-Verlag
About this paper
Cite this paper
Alexandre, A. et al. (2005). Intradiscal injection of oxygen-ozone gas mixture for the treatment of cervical disc herniations. In: Alexandre, A., Bricolo, A., Millesi, H. (eds) Advanced Peripheral Nerve Surgery and Minimal Invasive Spinal Surgery. Acta Neurochirurgica, vol 97. Springer, Vienna. https://doi.org/10.1007/3-211-27458-8_17
Download citation
DOI: https://doi.org/10.1007/3-211-27458-8_17
Publisher Name: Springer, Vienna
Print ISBN: 978-3-211-23368-9
Online ISBN: 978-3-211-27458-3
eBook Packages: MedicineMedicine (R0)