Collection

(Nano)bioelectroanalytical tools driven research in personalized medicine and nutrition

Submission status
Closed
Various contributions cover the breakthroughs of the last few years in the field of electrochemical biosensors coupled to micro/nano-structured materials to meet the needs in decentralized and personalized medicine and nutrition using non-invasive methods. This customized approach to medicine and nutrition is achieved by individual or multiplex interrogation of nucleic acids of different nature (ctDNAs, SNPs, mRNAs, miRNAs, lncRNAs, DNA oncoviruses, methylated nucleic acids, viral infection nucleic acids and nucleic acid sequences coding for allergens or adulterants), protein antigens of clinical or food safety relevance and their specific antibodies or autoantibodies. The interrogation of these molecular targets, so far little explored with electrochemical biosensors, may play a key role in establishing personalized medicine and nutrition strategies. The electrochemical biosensing approaches that this TC seeks to discuss would include the exploration of new surface chemistries and bioassay formats, emerging bioreceptors (aptamers, peptides, biomolecular switches, DNAzymes), nanomaterials (artificial, biological, multifunctional, multidomain, etc.), isothermal nucleic acid amplification and target recycling strategies and new technologies (phage display, HaloTag and CRISPR-Cas systems). Strategies to provide electrochemical biosensors with unique features beyond sensitivity and selectivity such as biofouling properties, real-time, continuous, wash and calibration-free operation are also emerging. Particular attention will be paid to bio-devices that have demonstrated pioneering and decisive capabilities to assist in these challenging issues and proven practical application to real-world challenges. Designs implemented on less conventional electrode substrates (paper, flexible, wearable) will also be particularly welcome.

Editors

  • María Jesús Lobo-Castañón María Jesús Lobo-Castañón  &

    María Jesús Lobo-Castañón

    María Jesús Lobo-Castañón is full Professor at the Department of Physical and Analytical Chemistry of University of Oviedo in Spain, leading the Electroanalysis research group. Her research interests focus on the development of electrochemical sensors for clinical diagnosis and food analysis, using different molecular recognition elements, such as enzymes, DNA and aptamers. She is Associate Editor in Talanta and member of the Editorial board of Analytical and Bioanalytical Chemistry.

  • Susana Campuzano Susana Campuzano

    Susana Campuzano

    Susana Campuzano is Professor at the Analytical Chemistry Department of the Chemistry Faculty of the Universidad Complutense de Madrid (Spain) where she is currently Head of “Electroanalysis and Electrochemical (Bio)Sensors” (GEBE) research group. Her areas of interest include the development of affinity-based electrochemical bioplatforms with potential for multiplexed and/or multi-omics determinations in precision medicine and nutrition. She is Associate Editor in Electroanalysis and member of the Editorial Board of Analytical & Bioanalytical Chemistry, Talanta and Biosensors & Bielectronics: X

Articles (6 in this collection)