Abstract
The objectives of this chapter are to examine the differences in the causes of death and disability between men and women and determine if diet and/or nutritional status are factors contributing to these differences. We will examine the role of nutrition during several of the critical periods in a woman’s life when stresses are increased. We will look at menstrual issues with emphasis on premenstrual syndrome (PMS), polycystic ovarian syndrome (PCOS), and pregnancy. Additionally, we will review two major diseases associated with female aging: autoimmune disease and osteoporosis.
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References
ACOG Committee Opinion. (1995). ACOG: Premenstrual syndrome. International Journal of Gynecology and Obstetrics, 50,, 80–84.
Ahluwalia, I. B., Holtzman, D., Mack, K. A., & Mokdad, A. (2003). Observations from the CDC. Health-related quality of life among women of reproductive age: Behavioral risk factor surveillance system (BRFSS), 1998–2001. Journal of Women’s Health, 12, 5–9.
Andreassen, H., Rungby, J., Dahlerup, J. F., & Mosekilde, L. (1997). Inflammatory bowel disease and osteoporosis. Scandinavian Journal of Gastroenterology, 32, 1247–1255.
Axelrod, L. (2001). Corticosteroid therapy. In K. L. Becker (Ed.), Principals and practice of endocrinology and metabolism (3rd ed., pp. 751–772). Philadelphia: Lippincott Williams & Wilkins.
Balbi, C., Musone, R., Menditto, A., Di Prisco, L., Cassese, E., D’Ajello, M., Ambriosio, D., & Cardone, A. (2000). Influence of menstrual factors and dietary habits on menstrual pain in adolescence age. European Journal of Obstetrics, Gynecology, and Reproductive Biology, 91, 143–148.
Balint, G., & Gergely, P., Jr. (1996). Clinical immunotoxicity of antirheumatic drugs. Inflammation Research, 45(Suppl. 2), S91–S95.
Barker, D. J. (1999). Fetal origins of cardiovascular disease. Annals of Medicine, 31(Suppl. 1), 3–6.
Becker, K. L. (2001). Principals and practice of endocrinology and metabolism. (3rd ed.). Philadelphia: Lippincott Williams & Wilkins.
Beers, M. H., & Berklow, R. (1999a). Diffuse connective tissue disease. In M. H. Beers & R. Berkow (Eds.), The merck manual of diagnosis and therapy (17th ed., pp. 416–423). Whitehouse Station, NJ: Merck Research Laboratory.
Beers, M. H., & Berklow, R. (1999b). Osteoporosis. In M. H. Beers & R. Berkow (Eds.), The Merck manual (17th ed., pp. 469–473). Whitehouse Station, NJ: Merck Research Laboratories.
Belluzzi, A. (2001). Polyunsaturated fatty acids and autoimmune diseases. In A. Bendich & R. J. Deckelbaum (Eds.), Primary and secondary preventive nutrition (pp. 271–287). Totowa, NJ: Humana Press.
Bendich, A. (2000). The potential for dietary supplements to reduce premenstrual syndrome (PMS) symptoms. Journal of the American College of Nutrition, 19, 3–12.
Bendich, A., & Deckelbaum, R. J. (2001a). Preventive nutrition: The comprehensive guide for health professionals (2nd ed.). Totowa, NJ: Humana Press.
Bendich, A., & Deckelbaum, R. J. (2001b). Primary and secondary preventive nutrition. Totowa, NJ: Humana Press.
Bendich, A., Leader, S., & Muhuri, P. (1999). Supplemental calcium for the prevention of hip fracture: Potential health-economic benefits. Clinical Therapeutics, 21, 1058–1072.
Bendich, A., Mallick, R., & Leader, S. (1997). Potential health economic benefits of vitamin supplementation. The Western Journal of Medicine, 166, 306–312.
Bendich, A., & Zilberboim, R. (2004). Drug-nutrient interactions and immune function. In J. I. Boullata & V. T. Armenti (Eds.), Handbook of drug-nutrient interactions (pp. 441–478). Totowa, NJ: Humana Press.
Berman, M. K., Taylor, M. L., & Freeman, E. (1990). Vitamin B-6 in premenstrual syndrome. Journal of the American Dietetic Association, 90, 859–861.
Berry, R. J., Li, Z., Erickson, J. D., Li, S., Moore, C. A., Wang, H., et al. (1999). Prevention of neural-tube defects with folic acid in China. China-U.S. Collaborative Project for Neural Tube Defect Prevention. The New England Journal of Medicine, 341, 1485–1490.
Bhattoa, H. P., Kiss, E., Bettembuk, P., & Balogh, A. (2001). Bone mineral density, biochemical markers of bone turnover, and hormonal status in men with systemic lupus erythematosus. Rheumatology International, 21, 97–102.
Blanco, R., Martinez-Taboada, V. M., Rodriguez-Valverde, V., Sanchez-Andrade, A., & Gonzalez-Gay, M. A. (1997). Successful therapy with danazol in refractory autoimmune thrombocytopenia associated with rheumatic diseases. British Journal of Rheumatology, 36, 1095–1099.
Block, G., Cox, C., Madans, J., Schreiber, G. B., Licitra, L., & Melia, N. (1988). Vitamin supplement use, by demographic characteristics. American Journal of Epidemiology, 127, 297–309.
Cassidy, J. T., & Hillman, L. S. (1997). Abnormalities in skeletal growth in children with juvenile rheumatoid arthritis. Rheumatic Diseases Clinics of North America, 23, 499–522.
Cauley, J. A., Robbins, J., Chen, Z., Cummings, S. R., Jackson, R. D., LaCroix, A. Z., Le Boff, M., Lewis, C. E., McGowan, J., Neuner, J., Pettinger, M., Stefanick, M. L., Wactawski-Wende, J., & Watts, N. B. (2003). Effects of estrogen plus progestin on risk of fracture and bone mineral density: The Women’s Health Initiative randomized trial. The Journal of the American Medical Association, 290, 1729–1738.
Cerhan, J. R., Saag, K. G., Merlino, L. A., Mikuls, T. R., & Criswell, L. A. (2003). Antioxidant micronutrients and risk of rheumatoid arthritis in a cohort of older women. American Journal of Epidemiology, 157, 345–354.
Chakmakjian, Z. H., Higgins, C. E., & Abraham, G. E. (1985). The effect of a nutritional supplement, Optivite® for women, on premenstrual tension syndromes: II. Effect on symptomatology, using a double blind cross-over design. Journal of Applied Nutrition, 37, 12–17.
Chapuy, M. C., Arlot, M. E., Duboeuf, F., Brun, J., Crouzet, B., Arnaud, S., Delmas, P. D., & Meunier, P. J. (1992). Vitamin D3 and calcium to prevent hip fractures in the elderly women. The New England Journal of Medicine, 327, 1637–1642.
Christian, R. C., Dumesic, D. A., Behrenbeck, T., Oberg, A. L., Sheedy, P. F., & Fitzpatrick, L. A. (2003). Prevalence and predictors of coronary artery calcification in women with polycystic ovary syndrome. The Journal of Clinical Endocrinology and Metabolism, 88, 2562–2568.
Chuong, C. J., Dawson, E. B., & Smith, E. R. (1990). Vitamin E levels in premenstrual syndrome. American Journal of Obstetrics and Gynecology, 163, 1591–1595.
Comstock, G. W., Burke, A. E., Hoffman, S. C., Helzlsouer, K. J., Bendich, A., Masi, A. T., Norkus, E. P., Malamet, R. I., & Gershwin, M. E. (1997). Serum concentrations of alpha tocopherol, beta carotene, and retinol preceding the diagnosis of rheumatoid arthritis and systemic lupus erythematosus. Annals of the Rheumatic Diseases, 56, 323–325.
Cruzan, C., & Fagan, T. (2002). Proceedings from: Understanding the biology of sex differences: Sex differences in immunity and autoimmunity. Washington, DC: Society for Women’s Health Research.
Cummings, S. R., Nevitt, M. C., Browner, W. S., Stone, K., Fox, K. M., Ensrud, K. E., Cauley, J., Black, D., & Vogt, T. M. (1995). Risk factors for hip fracture in white women. Study of Osteoporotic Fractures Research Group. The New England Journal of Medicine, 332, 767–773.
Czeizel, A. E. (2001). Folic acid-containing multivitamins and primary prevention of birth defects. In A. Bendich & R. J. Deckelbaum (Eds.), Preventive nutrition: The comprehensive guide for health professionals (2nd ed., pp. 349–371). Totowa, NJ: Humana Press.
Czeizel, A. E., & Dudas, I. (1992). Prevention of the first occurrence of neural-tube defects by periconceptional vitamin supplementation. The New England Journal of Medicine, 327, 1832–1835.
Daugherty, J. E. (1998). Treatment strategies for premenstrual syndrome. American Family Physician, 58, 183–188.
Dawson-Hughes, B., Harris, S. S., Krall, E. A., & Dallal, G. E. (1997). Effect of calcium and vitamin D supplementation on bone density in men and women 65 years of age or older. The New England Journal of Medicine, 337, 670–676.
de Onis, M., Villar, J., & Gulmezoglu, M. (1998). Nutritional interventions to prevent intrauterine growth retardation: Evidence from randomized controlled trials. European Journal of Clinical Nutrition, 52(Suppl. 1), S83–S93.
de Sousa, M. (1993). Circulation and distribution of iron: A key to immune interaction. In S. Cunningham-Rundles (Ed.), Nutrient modulation of the immune response. New York: Marcel Dekker, Inc.
Diegoli, M. S., da Fonseca, A. M., Diegoli, C. A., & Pinotti, J. A. (1998). A double-blind trial of four medications to treat severe premenstrual syndrome. International Journal of Gynecology and Obstetrics, 62, 63–67.
Division of Reproductive Health. (1999). Preterm Singleton Births—United States, 1989–1996.
Douglas, S. (2002). Premenstrual syndrome. Canadian Family Physician, 48, 1789–1797.
Dunaif, A., & Lobo, R. A. (2002). Toward optimal health: The experts discuss polycystic ovary syndrome. Journal of Women’s Health & Gender-Based Medicine, 11, 579–584.
Eastell, R. (2005). Calcium requirements during treatment of osteoporosis in women. In A. Bendich & R. J. Deckelbaum (Eds.), Preventive nutrition: The comprehensive guide for health professionals (3rd ed. pp. 425–432). Totowa, NJ: Humana Press.
Ebeling, P. R. (1999). Secondary causes of osteoporosis in men. In E. S. Orwoll (Ed.), Osteoporosis in men: The effects of gender on skeletal health (pp. 483–504). New York: Academic.
Elbon, S. M., Johnson, M. A., & Fischer, J. G. (1998). Milk consumption in older Americans. American Journal of Public Health, 88, 1221–1224.
Epidemiology Program Office. (1992). Recommendations for the use of folic acid to reduce the number of cases of spina bifida and other neural tube defects. http://www.cdc.gov/mmwr/preview/mmwrhtml/00019479.htm [on-line].
Facchinetti, F., Borella, P., Sances, G., Fioroni, L., Nappi, R. E., & Genazzani, A. R. (1991). Oral magnesium successfully relieves premenstrual mood changes. Obstetrics and Gynecology, 78, 177–181.
Facchinetti, F., Nappi, R. E., Sances, M. G., Neri, I., Grandinetti, G., & Genazzani, A. (1997). Effects of a yeast-based dietary supplementation on premenstrual syndrome. A double-blind placebo-controlled study. Gynecologic and Obstetric Investigation, 43, 120–124.
Facchinetti, F., Sances, G., Borella, P., Genazzani, A. R., & Nappi, G. (1991). Magnesium prophylaxis of menstrual migraine: Effects on intracellular magnesium. Headache, 31, 298–301.
Fairfield, K. M., & Fletcher, R. H. (2002). Vitamins for chronic disease prevention in adults: Scientific review. The Journal of the American Medical Association, 287, 3116–3126.
Fawzi, W. W., Msamanga, G. I., Spiegelman, D., Urassa, E. J., McGrath, N., Mwakagile, D., Antelman, G., Mbise, R., Herrera, G., Kapiga, S., Willett, W., & Hunter D. J. (1998). Randomised trial of effects of vitamin supplements on pregnancy outcomes and T cell counts in HIV-1-infected women in Tanzania. Lancet, 351, 1477–1482.
Frank, E., Bendich, A., & Denniston, M. (2000). Use of vitamin-mineral supplements by female physicians in the United States. The American Journal of Clinical Nutrition, 72, 969–975.
Freeman, E. W., Sammel, M. D., Rinaudo, P. J., & Sheng, L. (2004). Premenstrual syndrome as a predictor of menopausal symptoms. Obstetrics and Gynecology, 103, 960–966.
Galperin, C., Fernandes, G., Oliveira, R. M., & Gershwin, M. E. (2000). Nutritional modulation of autoimmune diseases. In M. E. Gershwin, J. B. German, & C. L. Keen (Eds.), Nutrition and immunology principals and practice (pp. 313–328). Totowa, NJ: Humana Press.
Gennari, C., Martini, G., & Nuti, R. (1998). Secondary osteoporosis. Aging Clinical and Experimental Research, 10, 214–224.
Goldenberg, R. L., Tamura, T., Neggers, Y., Copper, R. L., Johnston, K. E., DuBard, M. B., & Hauth, J. C. (1995). The effect of zinc supplementation on pregnancy outcome. The Journal of the American Medical Association, 274, 463–468.
Goldring, S. R. (2001). Osteoporosis associated with rheumatologic disorders. In R. Marcus, D. Feldman, & J. Kelsey (Eds.), Osteoporosis (2nd ed., Vol. 2, pp. 351–362). New York: Academic.
Gordon, C. M. (2003). Normal bone accretion and effects of nutritional disorders in childhood. Journal of Women’s Health, 12, 137–143.
Hanninen, Kaartinen, K., Rauma, A. L., Nenonen, M., Torronen, R., Hakkinen, A. S., Adlercreutz, H., & Laakso, J. (2000). Antioxidants in vegan diet and rheumatic disorders. Toxicology, 155, 45–53.
Heaney, R. P. (2001). Osteoporosis: Mineral, vitamins, and other micronutrients. In A. Bendich & R. J. Deckelbaum (Eds.), Preventive nutrition: The comprehensive guide for health professionals (2nd ed., pp. 271–292). Totowa, NJ: Humana Press.
Heller, H. J., & Sakhaee, K. (2001). Anticonvulsant-induced bone disease: A plea for monitoring and treatment. Archives of Neurology, 58, 1352–1353.
Institute of Medicine. (1998). Dietary reference intakes for thiamin, riboflavin, niacin, vitamin B6, folate, vitamin B12, pantothenic acid, biotin, and choline. Washington, DC: National Academy Press.
Jacobson, D. L., Gange, S. J., Rose, N. R., & Graham, N. M. (1997). Epidemiology and estimated population burden of selected autoimmune diseases in the United States. Clinical Immunology and Immunopathology, 84, 223–243.
Jamal, S. A., Browner, W. S., Bauer, D. C., & Cummings, S. R. (1998). Warfarin use and risk for osteoporosis in elderly women. Study of Osteoporotic Fractures Research Group. Annals of Internal Medicine, 128, 829–832.
Joffe, H., Soares, C. N., & Cohen, L. S. (2003). Assessment and treatment of hot flushes and menopausal mood disturbance. The Psychiatric Clinics of North America, 26, 563–580.
Johnston, R. B., Jr., & Staples, D. A. (1998). Use of folic acid-containing supplements among women of childbearing age—United States, 1997. http://www.cdc.gov/mmwr/preview/mmwrhtml/00051435.htm [on-line].
Jones, G., Riley, M., & Dwyer, T. (1999). Maternal smoking during pregnancy, growth, and bone mass in prepubertal children. Journal of Bone and Mineral Research, 14, 146–151.
Kaye, P. S. (2002). Osteoporosis and fracture as a result of gastrointestinal and hepatic disorders. Practical Gastroenterology, 15–28.
Keen, C. L., Bendich, A., & Willhite, C. C. (1993). Maternal nutrition and pregnancy outcome. New York: The New York Academy of Science.
Kiddy, D. S., Hamilton-Fairley, D., Bush, A., Short, F., Anyaoku, V., Reed, M. J., & Franks, S. (1992). Improvement in endocrine and ovarian function during dietary treatment of obese women with polycystic ovary syndrome. Clinical Endocrinology, 36, 105–111.
Klebanoff, M. A., Secher, N. J., Mednick, B. R., & Schulsinger, C. (1999). Maternal size at birth and the development of hypertension during pregnancy: A test of the Barker hypothesis. Archives of Internal Medicine, 159, 1607–1612.
Kleerekoper, A. (1996). Evaluation and treatment of postmenopausal osteoporosis. In M. Fauvus (Ed.), Primer on the metabolic bone disease and disorders of mineral metabolism (pp. 264–271). Philadelphia: Lippincott-Raven.
Koo, W. W., Walters, J. C., Esterlitz, J., Levine, R. J., Bush, A. J., & Sibai, B. (1999). Maternal calcium supplementation and fetal bone mineralization. Obstetrics and Gynecology, 94, 577–582.
Koplan, J. P., Annest, J. L., Layde, P. M., & Rubin, G. L. (1986). Nutrient intake and supplementation in the United States (NHANES II). American Journal of Public Health, 76, 287–289.
Krall, E. A. (2005). Osteoporosis. In R. Touger-Decker, D. A. Sirois, & C. C. Mobley (Eds.), Nutrition and oral medicine (pp. 261–272). Totowa, NJ: Humana Press.
Krall, E. A., & Dawson-Hughes, B. (1991). Smoking and bone loss among postmenopausal women. Journal of Bone and Mineral Research, 6, 331–338.
Krensky, A. M., Storm, T. B., & Bluestone, J. A. (2001). Immunomodulators: Immunosuppressive agents, tolerogens, and immunomodulators. In J. G. Hardman, L. E. Limbird, & A. G. Gilman (Eds.), The pharmacological basis of therapeutics (10th ed., pp. 1463–1484). New York: McGraw-Hill.
Kronenberg, F., & Fugh-Berman, A. (2002). Complementary and alternative medicine for menopausal symptoms: A review of randomized, controlled trials. Annals of Internal Medicine, 137, 805–813.
Langford, C. A., Klippel, J. H., Balow, J. E., James, S. P., & Sneller, M. C. (1998). Use of cytotoxic agents and cyclosporine in the treatment of autoimmune disease. Part 2: Inflammatory bowel disease, systemic vasculitis, and therapeutic toxicity. Annals of Internal Medicine, 129, 49–58.
Lappe, J. M., & Tinley, S. T. (1998). Prevention of osteoporosis in women treated for hereditary breast and ovarian carcinoma: A need that is overlooked. Cancer, 83, 830–834.
LeBoff, M. S., Kohlmeier, L., Hurwitz, S., Franklin, J., Wright, J., & Glowacki, J. (1999). Occult vitamin D deficiency in postmenopausal US women with acute hip fracture. The Journal of the American Medical Association, 281, 1505–1511.
Lee, S. J., & Kanis, J. A. (1994). An association between osteoporosis and premenstrual symptoms and postmenopausal symptoms. Bone and Mineral, 24, 127–134.
Leong, G. M., Center, J. R., Henderson, N. K., & Eisman, J. A. (2001). Glucocorticoid-induced osteoporosis. In R. Marcus, D. Feldman, & J. Kelsey (Eds.), Osteoporosis (2nd ed., Vol. 2, pp. 169–193). New York: Academic Press.
Lockshin, M. D. (2002). Sex ratio and rheumatic disease: Excerpts from an Institute of Medicine report. Lupus, 11, 662–666.
London, R. S., Bradley, L., & Chiamori, N. Y. (1991). Effect of a nutritional supplement on premenstrual symptomatology in women with premenstrual syndrome: A double-blind longitudinal study. Journal of the American College of Nutrition, 10, 494–499.
London, R. S., Murphy, L., Kitlowski, K. E., & Reynolds, M. A. (1987). Efficacy of alpha-tocopherol in the treatment of the premenstrual syndrome. Journal of Reproductive Medicine, 32, 400–404.
Looker, A. C., Orwoll, E. S., Johnston, C. C., Jr., Lindsay, R. L., Wahner, H. W., Dunn, W. L., Calvo, M. S., Harris, T. B., & Heyse, S. P. (1997). Prevalence of low femoral bone density in older U.S. adults from NHANES III. Journal of Bone and Mineral Research, 12, 1761–1768.
Loucks, A. B. (2003). Energy availability, not body fatness, regulates reproductive function in women. Exercise and Sport Sciences Reviews, 31, 144–148.
Lyle, B. J., Mares-Perlman, J. A., Klein, B. E., Klein, R., Palta, M., Bowen, P. E., & Greger, J. L. (1999). Serum carotenoids and tocopherols and incidence of age-related nuclear cataract. The American Journal of Clinical Nutrition, 69, 272–277.
Mack, K. A. & Ahluwalia, I. B. (2003). Observations from the CDC: Monitoring women’s health in the United States: Selected chronic disease indicators, 1991–2001 BRFSS. Journal of Women’s Health, 12, 309–314.
Marcus, R., Feldman, D., & Kelsey, J. (2001a). Osteoporosis (2nd ed., Vol. 1). New York: Academic Press.
Marcus, R., Feldman, D., & Kelsey, J. (2001b). Osteoporosis (2nd ed., Vol. 2). New York: Academic Press.
Marjoribanks, J., Proctor, M., & Farquhar, C. (2003). Nonsteroidal anti-inflammatory drugs for primary dysmenorrhoea. Cochrane Database of Systematic Reviews, 4, CD001751.
Marshall, D., Johnell, O., & Wedel, H. (1996). Meta-analysis of how well measures of bone mineral density predict occurrence of osteoporotic fractures. British Medical Journal, 312, 1254–1259.
Mazure, C. M., Keita, G. P., & Blehar, M. C. (2002). Summit on women and depression proceedings and recommendations. http://www.apa.org/pi/wpo/women&depression.pdf [on-line].
McAlindon, T. E., Gulin, J., Chen, T., Klug, T., Lahita, R., & Nuite, M. (2001). Indole-3-carbinol in women with SLE: Effect on estrogen metabolism and disease activity. Lupus, 10, 779–783.
McLean, J. A., & Barr, S. I. (2003). Cognitive dietary restraint is associated with eating behaviors, lifestyle practices, personality characteristics and menstrual irregularity in college women. Appetite, 40, 185–192.
Meisler, J. G. (2003). Toward optimal health: The experts provide a current perspective on perimenopause. Journal of Women’s Health, 12, 609–615.
Melhus, H., Michaelsson, K., Holmberg, L., Wolk, A., & Ljunghall, S. (1999). Smoking, antioxidant vitamins, and the risk of hip fracture. Journal of Bone and Mineral Research, 14, 129–135.
Merlino, L. A., Curtis, J., Mikuls, T. R., Cerhan, J. R., Criswell, L. A., & Saag, K. G. (2004). Vitamin D intake is inversely associated with rheumatoid arthritis: Results from the Iowa Women’s Health Study. Arthritis and Rheumatism, 50, 72–77.
Merrill, J. T., Dinu, A. R., & Lahita, R. G. (1996). Autoimmunity: The female connection. Medscape Women’s Health, 1, 5.
Mersereau, P., Kilker, M. N. K., Carter, H., Fassett, E., Williams, J., Flores, A., Prue, C., Williams, L., Mai, C., & Mulinare, J. (2004). Spina bifida and anencephaly before and after folic acid mandate—United States, 1995–1996 and 1999–2000. http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5317a3.htm [on-line].
Messina, M., & Hughes, C. (2003). Efficacy of soyfoods and soybean isoflavone supplements for alleviating menopausal symptoms is positively related to initial hot flush frequency. Journal of Medicinal Food, 6, 1–11.
Meyer, O. (2001). Atherosclerosis and connective tissue diseases. Joint Bone Spine, 68, 564–575.
Michelmore, K. F., Balen, A. H., & Dunger, D. B. (2001). Polycystic ovaries and eating disorders: Are they related? Human Reproduction, 16, 765–769.
Miller, K. K. (2003). Mechanisms by which nutritional disorders cause reduced bone mass in adults. Journal of Women’s Health, 12, 145–150.
Mira, M., Stewart, P. M., & Abraham, S. F. (1988). Vitamin and trace element status in premenstrual syndrome. The American Journal of Clinical Nutrition, 47, 636–641.
Mongey, A. B., & Hess, E. V. (1993). Drug and environmental effects on the induction of autoimmunity. The Journal of Laboratory and Clinical Medicine, 122, 652–657.
Mor, G., Sapi, E., Abrahams, V. M., Rutherford, T., Song, J., Hao, X. Y., et al. (2003). Interaction of the estrogen receptors with the Fas ligand promoter in human monocytes. Journal of Immunology, 170, 114–122.
Morgan, S. L., & Baggott, J. E. (1991). Role of dietary folate and oral folate supplements in the prevention of drug toxicity during anifolate therapy for nonneoplastic disease. In A. Bendich & C. E. Butterworth, Jr. (Eds.), Micronutrients in health and in disease prevention (pp. 333–358). New-York: Marcel Dekker, Inc.
Moss, A. J., Levy, A. S., Kim, I., & Park, Y. K. (1989). Use of vitamin and mineral supplements in the United States; current users, types of products and nutrients (Rep. No. Advanced Data no. 174). Hyattsville, MD: National Center for Health Statistics.
MRC Vitamin Study Research Group. (1991). Prevention of neural tube defects: Results of the Medical Research Council Vitamin Study. Lancet, 338, 131–137.
National Vital Statistics. (2002). Ten leading causes of death, by sex, race, and age. http://www.cdc.gov/nchs/fastats/pdf/nvsr50_16t1.pdf [on-line].
Newkirk, M. M., LePage, K., Niwa, T., & Rubin, L. (1998). Advanced glycation endproducts (AGE) on IgG, a target for circulating antibodies in North American Indians with rheumatoid arthritis (RA). Cellular & Molecular Biology (Noisy-Le-Grand), 44, 1129–1138.
Nieves, J. W., Komar, L., Cosman, F., & Lindsay, R. (1998). Calcium potentiates the effect of estrogen and calcitonin on bone mass: review and analysis. The American Journal of Clinical Nutrition, 67, 18–24.
NIH Consensus Development Panel on Optimal Calcium Intake. (1994). NIH Consensus conference. Optimal calcium intake. The Journal of the American Medical Association, 272, 1942–1948.
Norman, R. J., Noakes, M., Wu, R., Davies, M. J., Moran, L., & Wang, J. X. (2004). Improving reproductive performance in overweight/obese women with effective weight management. Human Reproduction Update, 10, 267–280.
Norman, R. J., Wu, R., & Stankiewicz, M. T. (2004). 4: Polycystic ovary syndrome. The Medical Journal of Australia, 180, 132–137.
Oakley, G. P., Jr. (1998). Eat right and take a multivitamin. The New England Journal of Medicine, 338, 1060–1061.
Oakley, G. P., Jr., & Erickson, J. D. (1995). Vitamin A and birth defects. Continuing caution is needed. The New England Journal of Medicine, 333, 1414–1415.
Okey, R., Stewart, J. A., & Greenwood, M. L. (1930). Studies of the metabolism of women. IV. The calcium and inorganic phosphorus in the blood of normal women at the various stages of the monthly cycle. The Journal of Biological Chemistry, 87, 91–102.
Orstavik, R. E., Haugeberg, G., Mowinckel, P., Hoiseth, A., Uhlig, T., Falch, J. A., Halse, J. I., McCloskey, E., & Kvien, T. K. (2004). Vertebral deformities in rheumatoid arthritis: A comparison with population-based controls. Archives of Internal Medicine, 164, 420–425.
Orwoll, E. S. (1999). The prevention and therapy of osteoporsis in men. In E. S. Orwoll (Ed.), Osteoporosis in men: The effects of gender on skeletal health (pp. 553–569). New York: Academic.
Patterson, R. E., Kristal, A. R., & Neuhouser, M. L. (2001). Vitamin Supplements and Cancer Risk. In A. Bendich & R. J. Deckelbaum (Eds.), Primary and secondary preventive nutrition (pp. 21–43). Totowa, NJ: Humana Press.
Penland, J. G., & Johnson, P. E. (1993). Dietary calcium and manganese effects on menstrual cycle symptoms. American Journal of Obstetrics and Gynecology, 168, 1417–1423.
Pereda, C. A., & Eastell, R. (2001). Calcium requirements during treatment of osteoporosis in women. In A. Bendich & R. J. Deckelbaum (Eds.), Primary and secondary preventive nutrition (pp. 307–321). Totowa, NJ: Humana Press.
Petri, M. A., Lahita, R. G., Van Vollenhoven, R. F., Merrill, J. T., Schiff, M., Ginzler, E. M., Strand, V., Kunz, A., Gorelick, K. J., Schwartz, K. E., & GL601 Study Group. (2002). Effects of prasterone on corticosteroid requirements of women with systemic lupus erythematosus: A double-blind, randomized, placebo-controlled trial. Arthritis and Rheumatism, 46, 1820–1829.
Ramakrishnan, U., & Huffman, S. L. (2001). Multiple micronutrient malnutrition; What can be done? In R. D. Semba & M. W. Bloem (Eds.), Nutrition and health in developing countries (pp. 365–391). Totowa, NJ: Humana Press.
Reid, I. R., Ames, R. W., Evans, M. C., Gamble, G. D., & Sharpe, S. J. (1995). Long-term effects of calcium supplementation on bone loss and fractures in postmenopausal women: A randomized controlled trial. The American Journal of Medicine, 98, 331–335.
Rider, V., Jones, S., Evans, M., Bassiri, H., Afsar, Z., & Abdou, N. I. (2001). Estrogen increases CD40 ligand expression in T cells from women with systemic lupus erythematosus. The Journal of Rheumatology, 28, 2644–2649.
Roitt, I. M., & Delves, P. J. (2001). Roitt’s essential immunology (10th ed.). Malden, MA: Blackwell Science, Inc.
Rose, N. R. (2002). Mechanisms of autoimmunity. Seminars in Liver Disease, 22, 387–394.
Rossouw, J. E., Anderson, G. L., Prentice, R. L., LaCroix, A. Z., Kooperberg, C., Stefanick, M. L., Jackson, R., D., Beresford, S. A., Howard, B. V., Johnson, K. C., Kotchen, J. M., Ockene, J., & The Writing Group for the Women’s Health Initiative Investigators. (2002). Risks and benefits of estrogen plus progestin in healthy postmenopausal women: Principal results from the Women’s Health Initiative randomized controlled trial. The Journal of the American Medical Association, 288, 321–333.
Satia-Abouta, J., Kristal, A. R., Patterson, R. E., Littman, A. J., Stratton, K. L., & White, E. (2003). Dietary supplement use and medical conditions: The VITAL study. American Journal of Preventive Medicine, 24, 43–51.
Scholl, T. O. (2001). Maternal nutrition and preterm delivery. In A. Bendich & R. J. Deckelbaum (Eds.), Preventive nutrition: The comprehensive guide for health professionals (2nd ed., pp. 387–413). Totowa, NJ: Humana Press.
Scholl, T. O., Hediger, M. L., Bendich, A., Schall, J. I., Smith, W. K., & Krueger, P. M. (1997). Use of multivitamin/mineral prenatal supplements: Influence on the outcome of pregnancy. American Journal of Epidemiology, 146, 134–141.
Schorah, C. J., & Smithells, R. W. (1991). A possible role for preconception multivitamin supplementation in the prevention or the recurrence of neural tube defects. In A. Bendich & C. E. Butterworth (Eds.), Micronutrients in health and disease prevention (pp. 263–285). New York: Marcel Decker.
Shikany, J. M., Patterson, R. E., Agurs-Collins, T., & Anderson, G. (2003). Antioxidant supplement use in Women’s Health Initiative participants. Journal of Women’s Health, 36, 379–387.
Sifton, D. W. (2001). Physicians’s desk reference. (55th ed.). Montvale, NJ: Medical Economics Company, Inc.
Singer, B. R., McLauchlan, G. J., Robinson, C. M., & Christie, J. (1998). Epidemiology of fractures in 15,000 adults: The influence of age and gender. The Journal of Bone and Joint Surgery. British Volume, 80, 243–248.
Smithells, R. W., Sheppard, S., Schorah, C. J., Seller, M. J., Nevin, N. C., Harris, R., Read, A. P., & Fielding, D. W. (1980). Possible prevention of neural-tube defects by periconceptional vitamin supplementation. Lancet, 1, 339–340.
Solomon, D. H., Karlson, E. W., Rimm, E. B., Cannuscio, C. C., Mandl, L. A., Manson, J. E., Stampfer, M. J., & Curhan, G. C. (2003). Cardiovascular morbidity and mortality in women diagnosed with rheumatoid arthritis. Circulation, 107, 1303–1307.
Soules, M. R., Sherman, S., Parrott, E., Rebar, R., Santoro, N., Utian, W., & Woods, N. (2001). Executive summary: Stages of Reproductive Aging Workshop (STRAW). Fertility and Sterility, 76, 874–878.
Standing Committee on the Scientific Evaluation of Dietary Reference Intakes Food and Nutrition Board Institute of Medicine. (1997). Dietary reference intake for calcium, phosphorous, magnesium, vitamin D, and fluoride (S-9 ed.). Washington, DC: National Academy Press.
Stearns, V., Beebe, K. L., Iyengar, M., & Dube, E. (2003). Paroxetine controlled release in the treatment of menopausal hot flashes: a randomized controlled trial. The Journal of the American Medical Association, 289, 2827–2834.
Stock, J. L. (1996). Drug therapy. In C. J. Rosen (Ed.), Osteoporosis: Diagnostic and therapeutic principles (pp. 173–187). Totowa, NJ: Humana Press.
Subar, A. F., & Block, G. (1990). Use of vitamin and mineral supplements: Demographics and amounts of nutrients consumed. The 1987 Health Interview Survey. American Journal of Epidemiology, 132, 1091–1101.
Thomas, F., Renaud, F., Benefice, E., de Meeus, T., & Guegan, J. F. (2001). International variability of ages at menarche and menopause: Patterns and main determinants. Human Biology; An International Record of Research, 73, 271–290.
Thys-Jacobs, S., Alvir, J. M., & Fratarcangelo, P. (1995). Comparative analysis of three PMS assessment instruments—the identification of premenstrual syndrome with core symptoms. Psychopharmacology Bulletin, 31, 389–396.
Thys-Jacobs, S., Ceccarelli, S., Bierman, A., Weisman, H., Cohen, M. A., & Alvir, I. (1989). Calcium supplementation in premenstrual syndrome: A randomized crossover trial. Journal of General Internal Medicine, 4, 183–189.
Thys-Jacobs, S., Donovan, D., Papadopoulos, A., Sarrel, P., & Bilezikian, J. P. (1999). Vitamin D and calcium dysregulation in the polycystic ovarian syndrome. Steroids, 64, 430–435.
Thys-Jacobs, S., Starkey, P., Bernstein, D., & Tian, J. (1998). Calcium carbonate and the premenstrual syndrome: Effects on premenstrual and menstrual symptoms. Premenstrual Syndrome Study Group. American Journal of Obstetrics and Gynecology, 179, 444–452.
Valmadrid, C., Voorhees, C., Litt, B., & Schneyer, C. R. (2001). Practice patterns of neurologists regarding bone and mineral effects of antiepileptic drug therapy. Archives of Neurology, 58, 1369–1374.
Walker, A. F., De Souza, M. C., Vickers, M. F., Abeyasekera, S., Collins, M. L., & Trinca, L. A. (1998). Magnesium supplementation alleviates premenstrual symptoms of fluid retention. Journal of Women’s Health, 7, 1157–1165.
Ward, M. W., & Holimon, T. D. (1999). Calcium treatment for premenstrual syndrome. The Annals of Pharmacotherapy, 33, 1356–1358.
Welty, F. K. (2003). Nutrition and Women’s Health Symposium. Introduction. Journal of Women’s Health, 12, 105–108.
West, K. P., Jr., Katz, J., Khatry, S. K., LeClerq, S. C., Pradhan, E. K., Shrestha, S. R., Connor, P. B., Dali, S. M., Christian, P., Pokhrel, R. P., & Sommer, A. (1999). Double blind, cluster randomised trial of low dose supplementation with vitamin A or beta carotene on mortality related to pregnancy in Nepal. The NNIPS-2 Study Group. British Medical Journal, 318, 570–575.
White, E., Patterson, R. E., Kristal, A. R., Thornquist, M., King, I., Shattuck, A. L., Evans, I., Satia-Abouta, J., Littman, A. J., & Potter, J. D. (2004). Vitamins and lifestyle cohort study: Study design and characteristics of supplement users. American Journal of Epidemiology, 159, 83–93.
Willett, W. C., Sampson, L., & Bain, C. (1981). Vitamin supplement use among registered nurses. The American Journal of Clinical Nutrition, 34, 1121–1125.
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Bendich, A., Zilberboim, R. (2006). Major Stressors in Women’s Health. In: Yehuda, S., Mostofsky, D.I. (eds) Nutrients, Stress, and Medical Disorders. Nutrition and Health. Humana Press. https://doi.org/10.1385/1-59259-952-4:287
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