Abstract
In recent times, the population is more prone to getting sick than the times before. This widespread occurrence of diseases warrants a diagnostic system in place which can help us acknowledge its presence even during the early stages, especially in the case of life-threatening ones. Nanotheranostics is a field which helps us with the same; it not only helps us to diagnose a disease in its earlier stages but also helps treat it at the point of care itself. Nanotheranostics include diagnosis at a nanoscale level, using tools such as MRI, PET-CT scan, etc., as well as providing therapy at the nanoscale level using tools like chemotherapy, radiotherapy, photodynamic therapy, etc. Both systems are conjugated on a nanocarrier which can be a polymer, lipid, or inorganic material depending upon the properties required. This new age medical system has also opened avenues for something called personalized medicine.
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References
Aioub M, Panikkanvalappil SR, El-Sayed MA (2017) Platinum-coated gold nanorods: efficient reactive oxygen scavengers that prevent oxidative damage toward healthy, untreated cells during plasmonic photothermal therapy. ACS Nano 11(1):579–586
Ale A, Ermolayev V, Herzog E, Cohrs C, de Angelis MH, Ntziachristos V (2012) FMT-XCT: in vivo animal studies with hybrid fluorescence molecular tomography-X-ray computed tomography. Nat Methods 9(6):615–620
Ali MRK et al (2016) Simultaneous time-dependent surface-enhanced raman spectroscopy, metabolomics, and proteomics reveal cancer cell death mechanisms associated with gold nanorod photothermal therapy. J Am Chem Soc 138(47):15434–15442
Ali MRK et al (2017) Efficacy, long-term toxicity, and mechanistic studies of gold nanorods photothermal therapy of cancer in xenograft mice. Proc Natl Acad Sci U S A 114(15):E3110–E3118
Al-Jamal T, Kostarelos K (2011) Liposomes: from a clinically established drug delivery system to a nanoparticle platform for theranostic nanomedicine. Acc Chem Res 44(10):1094–1104
Allison RR, Moghissi K (2013) Photodynamic therapy (PDT): PDT mechanisms. Clin Endosc 46(1):24–29
Andreozzi E, Seo JW, Ferrara K, Louie A (2011) Novel method to label solid lipid nanoparticles with 64 Cu for positron emission tomography imaging. Bioconjug Chem 22(4):808–818
Arifin DR et al (2011) Trimodal gadolinium-gold microcapsules containing pancreatic islet cells restore normoglycemia in diabetic mice and can be tracked by using US, CT, and positive-contrast MR imaging. Radiology 260(3):790–798
Bangham D, Standish MM, Watkins JC (1965) Diffusion of univalent ions across the lamellae of swollen phospholipids. J Mol Biol 13(1):238–252
Bar-Shalom R, Valdivia AY, Blaufox MD (2000) PET imaging in oncology. Semin Nucl Med 30(3):150–185
Blanco E, Kessinger CW, Sumer BD, Gao J (2009) Multifunctional micellar nanomedicine for cancer therapy. Exp Biol Med (Maywood) 234(2):123–131
Blau R, Krivitsky A, Epshtein Y, Satchi-Fainaro R (2016) Are nanotheranostics and nanodiagnostics-guided drug delivery. Drug Resist Updat Elsevier 27:39–58
Boswell A et al (2008) Synthesis, characterization, and biological evaluation of integrin alphavbeta3-targeted PAMAM dendrimers. Mol Pharm 5(4):527–539
Bulbake U et al (2017) Liposomal formulations in clinical use: an updated review. Pharmaceutics 9(2):12
Burguma MJ, Evansa SJ, Jenkins GJ, Doak SH, Clift MJD (2018) Considerations for the human health implications of nanotheranostics. Handbook of nanomaterials for cancer theranostics. Elsevier
Cai Q-Y et al (2007) Colloidal gold nanoparticles as a blood-pool contrast agent for X-ray computed tomography in mice. Investig Radiol 42(12):797–806
Calixto GMF et al (2016) Nanotechnology-based drug delivery systems for photodynamic therapy of cancer: a review. Molecules 21(3):342
Celli JP et al (2010) Imaging and photodynamic therapy: mechanisms, monitoring and optimization. Chem Rev 110(5):2795–2838
Chakravarty R et al (2014) Matching the decay half-life with the biological half-life: ImmunoPET imaging with (44)Sc-labeled cetuximab Fab fragment. Bioconjug Chem 25(12):2197–2204
Chen J, Pei Y, Chen Z, Cai J (2010a) Quantum dot labeling based on near-field optical imaging of CD44 molecules. Micron 41(3):198–202
Chen W-T et al (2010b) Dynamic contrast-enhanced folate-receptor-targeted MR imaging using a Gd-loaded PEG-dendrimer-folate conjugate in a mouse xenograft tumor model. Mol Imaging Biol MIB Off Publ Acad Mol Imaging 12(2):145–154
Chen C-L et al (2013) Photothermal cancer therapy via femtosecond-laser-excited FePt nanoparticles. Biomaterials 34(4):1128–1134
Chen L et al (2015a) Radionuclide (131)I labeled reduced graphene oxide for nuclear imaging guided combined radio- and photothermal therapy of cancer. Biomaterials 66:21–28
Chen Q, Ke H, Dai Z, Liu Z (2015b) Nanoscale theranostics for physical stimulus-responsive cancer therapies. Biomaterials Elsevier 73:214–230
Cho H, Lai TC, Tomoda K, Kwon GS (2015) Polymeric micelles for multi-drug delivery in cancer. AAPS PharmSciTech 16(1):10–20
Chopra (2004) [74As]-labeled monoclonal antibody against anionic phospholipids. In: Molecular imaging and contrast agent database (MICAD). National Center for Biotechnology Information (US), Bethesda
Chrastina A, Massey KA, Schnitzer JE (2011) Overcoming in vivo barriers to targeted nanodelivery: overcoming barriers to targeted nanodelivery. Wiley Interdiscip Rev Nanomed Nanobiotechnol 3(4):421–437
Chu M et al (2013) Near-infrared laser light mediated cancer therapy by photothermal effect of Fe3O4 magnetic nanoparticles. Biomaterials 34(16):4078–4088
Cormode P et al (2008) Nanocrystal core high-density lipoproteins: a multimodality contrast agent platform. Nano Lett 8(11):3715–3723
Cormode P et al (2010) Atherosclerotic plaque composition: analysis with multicolor CT and targeted gold nanoparticles. Radiology 256(3):774–782
Dai Z (ed) (2016) Advances in nanotheranostics I: design and fabrication of theranosic nanoparticles. Springer-Verlag, Berlin/Heidelberg
Dai H, Lin GX, Liu Z, Wu R, Chen Y (2017) Biocompatible 2D titanium carbide (MXenes) composite nanosheets for pH-responsive MRI-guided tumor hyperthermia. Chem Mater 29(20):8637–8652
Dawidczyk CM, Russell LM, Searson PC (2014) Nanomedicines for cancer therapy: state-of-the-art and limitations to pre-clinical studies that hinder future developments. Front Chem 2:69
de Smet M, Heijman E, Langereis S, Hijnen NM, Grüll H (2011) Magnetic resonance imaging of high intensity focused ultrasound mediated drug delivery from temperature-sensitive liposomes: an in vivo proof-of-concept study. J Control Release 150(1):102–110
de Vries JM et al (2005) Magnetic resonance tracking of dendritic cells in melanoma patients for monitoring of cellular therapy. Nat Biotechnol 23(11):1407–1413
de Vries A, Custers E, Lub J, van den Bosch S, Nicolay K, Grüll H (2010) Block-copolymer-stabilized iodinated emulsions for use as CT contrast agents. Biomaterials 31(25):6537–6544
Devaraj K, Keliher EJ, Thurber GM, Nahrendorf M, Weissleder R (2009) 18F labeled nanoparticles for in vivo PET-CT imaging. Bioconjug Chem 20(2):397–401
DeVita VT, Chu E (2008) A history of cancer chemotherapy. Cancer Res 68(21):8643–8653
Dougherty J, Grindey GB, Fiel R, Weishaupt KR, Boyle DG (1975) Photoradiation therapy. II. Cure of animal tumors with hematoporphyrin and light. J Natl Cancer Inst 55(1):115–121
Duan X et al (2013) Smart pH-sensitive and temporal-controlled polymeric micelles for effective combination therapy of doxorubicin and disulfiram. ACS Nano 7(7):5858–5869
Ducongé F et al (2008) Fluorine-18-labeled phospholipid quantum dot micelles for in vivo multimodal imaging from whole body to cellular scales. Bioconjug Chem 19(9):1921–1926
Dunne M, Zheng J, Rosenblat J, Jaffray DA, Allen C (2011) APN/CD13-targeting as a strategy to alter the tumor accumulation of liposomes. J Contr Release 154(3):298–305
Espinosa R, Di Corato J, Kolosnjaj-Tabi P, Flaud TP, Wilhelm C (2016) Duality of iron oxide nanoparticles in cancer therapy: amplification of heating efficiency by magnetic hyperthermia and photothermal bimodal treatment. ACS Nano 10(2):2436–2446
Feng J et al (2017) Bioconjugation of gold nanobipyramids for SERS detection and targeted photothermal therapy in breast cancer. ACS Biomater Sci Eng 3(4):608–618
Ferber S et al (2014) Polymeric nanotheranostics for real-time non-invasive optical imaging of breast cancer progression and drug release. Cancer Lett 352(1):81–89
Fortin-Ripoche J-P et al (2006) Magnetic targeting of magnetoliposomes to solid tumors with MR imaging monitoring in mice: feasibility. Radiology 239(2):415–424
Glasgow DK, Chougule MB (2015) Recent developments in active tumor targeted multifunctional nanoparticles for combination chemotherapy in cancer treatment and imaging. J Biomed Nanotechnol 11(11):1859–1898
Glaus C, Rossin R, Welch MJ, Bao G (2010) In vivo evaluation of 64Cu-labeled magnetic nanoparticles as a dual-modality PET/MR imaging agent. Bioconjug Chem 21(4):715–722
Gou Y, Zhou M, Miao D, Su G (2018) Bio-inspired protein-based nanoformulations for cancer theranostics. Front Pharmacol 9(421)
Hao N, Li L, Tang F (2014) Shape-mediated biological effects of mesoporous silica nanoparticles. J Biomed Nanotechnol 10(10):2508–2538
Herth MM et al (2009) Radioactive labeling of defined HPMA-based polymeric structures using [18F]FETos for in vivo imaging by positron emission tomography. Biomacromolecules 10(7):1697–1703
Herth MM, Barz M, Jahn M, Zentel R, Rösch F (2010) 72/74As-labeling of HPMA based polymers for long-term in vivo PET imaging. Bioorg Med Chem Lett 20(18):5454–5458
Huang R et al (2011) Chlorotoxin-modified macromolecular contrast agent for MRI tumor diagnosis. Biomaterials 32(22):5177–5186
Huang P et al (2014) Dye-loaded ferritin nanocages for multimodal imaging and photothermal therapy. Adv Mater Deerfield Beach Fla 26(37):6401–6408
Huh Y-M et al (2005) In vivo magnetic resonance detection of cancer by using multifunctional magnetic nanocrystals. J Am Chem Soc 127(35):12387–12391
Hussein A, Zagho MM, Nasrallah GK, Elzatahry AA (2018) Recent advances in functional nanostructures as cancer photothermal therapy. Int J Nanomedicine 13:2897–2906
Hyde D et al (2009) Hybrid FMT–CT imaging of amyloid-β plaques in a murine Alzheimer’s disease model. NeuroImage 44(4):1304–1311
Jo SD, Ku SH, Won Y-Y, Kim SH, Kwon IC (2016) Targeted nanotheranostics for future personalized medicine: recent progress in cancer therapy. Theranostics Ivyspring 6(9):1362–1377
Kakizawa Y, Furukawa S, Kataoka K (2004) Block copolymer-coated calcium phosphate nanoparticles sensing intracellular environment for oligodeoxynucleotide and siRNA delivery. J Control Release Off J Control Release Soc 97(2):345–356
Karlsson H, Birch J, Halim J, Barsoum MW, Persson POÅ (2015) Atomically resolved structural and chemical investigation of single MXene sheets. Nano Lett 15(8):4955–4960
Kim H, Lee S, Chen X (2013) Nanotheranostics for personalized medicine. Expert Rev Mol Diagn 13(3):257–269
Kinsella JM et al (2011) X-ray computed tomography imaging of breast cancer by using targeted peptide-labeled bismuth sulfide nanoparticles. Angew Chem Int Ed 50(51):12308–12311
Kudr J et al (2017) Magnetic nanoparticles: from design and synthesis to real world applications. Nano 7(9)
Kunjachan S, Ehling J, Storm G, Kiessling F, Lammers T (2013) Noninvasive imaging of nanomedicines and nanotheranostics: principles, progress, and prospects. Chem Rev ACS Publications. Nanoparticles in medicines 115:10907–10937
Kunjachan S et al (2014) Passive versus active tumor targeting using RGD- and NGR-modified polymeric nanomedicines. Nano Lett 14(2):972–981
Lammers T, Kiessling F, Hennink WE, Storm G (2010) Nanotheranostics and image-guided drug delivery: current concepts and future directions. Mol Pharm Am Chem Soc 7(6):1899–1912
Li X et al (2017) Nanostructured phthalocyanine assemblies with protein-driven switchable photoactivities for biophotonic imaging and therapy. J Am Chem Soc 139(31):10880–10886
Li X, Lee S, Yoon J (2018) Supramolecular photosensitizers rejuvenate photodynamic therapy. Chem Soc Rev 47(4):1174–1188
Liang C et al (2014) Tumor metastasis inhibition by imaging-guided photothermal therapy with single-walled carbon nanotubes. Adv Mater Deerfield Beach Fla 26(32):5646–5652
Licha K, Olbrich C (2005) Optical imaging in drug discovery and diagnostic applications. Adv Drug Deliv Rev 57(8):1087–1108
Lin J et al (2016) Multimodal imaging guided cancer phototherapy by versatile biomimetic theranostics with UV and γ irradiation protection. Adv Mater Deerfield Beach Fla 28(17):3273–3279
Lin H, Wang X, Yu L, Chen Y, Shi J (2017) Two-dimensional ultrathin MXene ceramic nanosheets for photothermal conversion. Nano Lett 17(1):384–391
Locatelli E et al (2012) Biocompatible nanocomposite for PET/MRI hybrid imaging. Int J Nanomedicine 7:6021–6033
Long M, van Laarhoven HWM, Bulte JWM, Levitsky HI (2009) Magnetovaccination as a novel method to assess and quantify dendritic cell tumor antigen capture and delivery to lymph nodes. Cancer Res 69(7):3180–3187
Lorusso V et al (2014) Non-pegylated liposome-encapsulated doxorubicin citrate plus cyclophosphamide or vinorelbine in metastatic breast cancer not previously treated with chemotherapy: a multicenter phase III study. Int J Oncol 45(5):2137–2142
Lucky SS, Soo KC, Zhang Y (2015) Nanoparticles in photodynamic therapy. Chem Rev 115(4):1990–2042
Luo K et al (2009) Functional L-lysine dendritic macromolecules as liver-imaging probes. Macromol Biosci 9(12):1227–1236
Ma Y, Huang J, Song S, Chen H, Zhang Z (2013) Cancer-targeted nanotheranostics: recent advances. Small J.:1–19 Wiley
Medarova Z, Pham W, Kim Y, Dai G, Moore A (2006) In vivo imaging of tumor response to therapy using a dual-modality imaging strategy. Int J Cancer 118(11):2796–2802
Meng Z, Hou W, Zhou H, Zhou L, Chen H, Wu C (2018) Therapeutic considerations and conjugated polymer-based photosensitizers for photodynamic therapy. Macromol Rapid Commun 39(5)
Menon JU, Jadeja P, Tambe P, Vu K, Yuan B, Nguyen KT (2013) Nanomaterials for photo-based diagnostic and therapeutic applications. Theranostics 3(3):152–166. https://doi.org/10.7150/thno.5327
Mikhail S, Allen C (2010) Poly(ethylene glycol)-b-poly(epsilon-caprolactone) micelles containing chemically conjugated and physically entrapped docetaxel: synthesis, characterization, and the influence of the drug on micelle morphology. Biomacromolecules 11(5):1273–1280
Mikhaylov G et al (2011) Ferri-liposomes as an MRI-visible drug-delivery system for targeting tumours and their microenvironment. Nat Nanotechnol 6(9):594–602
Mountz JM, Alavi A, Mountz JD (2012) Emerging optical and nuclear medicine imaging methods in rheumatoid arthritis. Nat Rev Rheumatol 8(12):719–728
Müller C et al (2014) Promising prospects for 44Sc-/47Sc-based theragnostics: application of 47Sc for radionuclide tumor therapy in mice. J Nucl Med 55(10):1658–1664
Nahrendorf M et al (2009) Hybrid in vivo FMT-CT imaging of protease activity in atherosclerosis with customized nanosensors. Arterioscler Thromb Vasc Biol 29(10):1444–1451
Ntziachristos V, Weissleder R (2001) Experimental three-dimensional fluorescence reconstruction of diffuse media by use of a normalized born approximation. Opt Lett 26(12):893–895
Ntziachristos V, Tung C-H, Bremer C, Weissleder R (2002) Fluorescence molecular tomography resolves protease activity in vivo. Nat Med 8(7):757–760
Ntziachristos V, Bremer C, Weissleder R (2003) Fluorescence imaging with near-infrared light: new technological advances that enable in vivo molecular imaging. Eur Radiol 13(1):195–208
Nwe K et al (2009) A new approach in the preparation of dendrimer-based bifunctional diethylenetriaminepentaacetic acid MR contrast agent derivatives. Bioconjug Chem 20(7):1412–1418
Pedrosa P et al (2015) Gold nanotheranostics: proof-of-concept or clinical tool? Nano 5(4):1853–1879
Pérez-Campaña C et al (2013) Biodistribution of different sized nanoparticles assessed by positron emission tomography: a general strategy for direct activation of metal oxide particles. ACS Nano 7(4):3498–3505
Pérez-Medina C et al (2016) Nanoreporter PET predicts the efficacy of anti-cancer nanotherapy. Nat Commun 7
Petersen L et al (2011) 64Cu loaded liposomes as positron emission tomography imaging agents. Biomaterials 32(9):2334–2341
Pichler J, Wehrl HF, Kolb A, Judenhofer MS (2008) Positron emission tomography/magnetic resonance imaging: the next generation of multimodality imaging? Semin Nucl Med 38(3):199–208
Pressly ED et al (2007) Structural effects on the biodistribution and positron emission tomography (PET) imaging of well-defined (64)Cu-labeled nanoparticles comprised of amphiphilic block graft copolymers. Biomacromolecules 8(10):3126–3134
Roesch (2012) Scandium-44: benefits of a long-lived PET radionuclide available from the (44)Ti/(44)Sc generator system. Curr Radiopharm 5(3):187–201
Shanmugam V, Selvakumar S, Yeh C-S (2014) Near-infrared light-responsive nanomaterials in cancer therapeutics. Chem Soc Rev 43(17):6254–6287
Sharma R, Mody N, Vyas SP (2017) Bioinspired nanotheranostics. Bipolymer based composites, vol 609. Elsevier, pp 279–288.
Sohail A, Ahmad Z, Bég OA, Arshad S, Sherin L (2017) A review on hyperthermia via nanoparticle-mediated therapy. Bull Cancer (Paris) 104(5):452–461
Sonali, Viswanadh MK, Singh RP, Agrawal P, Mehata AK, Pawde DM, Narendra, Sonkar R, Muthu MS (2018) Nanotheranostics: emerging strategies for early diagnosis and therapy of brain cancer. Nanotheranostics Ivyspring 2:70–86
Spikes D (1985) The historical development of ideas on applications of photosensitized reactions in the health sciences. In: Bensasson RV, Jori G, Land EJ, Truscott TG (eds) Primary photo-processes in biology and medicine. Springer US, Boston, pp 209–227
Sun X et al (2018) Aggregation-induced emission nanoparticles encapsulated with PEGylated nano graphene oxide and their applications in two-photon fluorescence bioimaging and photodynamic therapy in vitro and in vivo. ACS Appl Mater Interfaces 10(30):25037–25046
Swanson D et al (2008) Targeted gadolinium-loaded dendrimer nanoparticles for tumor-specific magnetic resonance contrast enhancement. Int J Nanomedicine 3(2):201–210
Tang Y et al (2015) An aptamer-targeting photoresponsive drug delivery system using ‘off–on’ graphene oxide wrapped mesoporous silica nanoparticles. Nanoscale 7(14):6304–6310
Terreno E, Castelli DD, Viale A, Aime S (2010) Challenges for molecular magnetic resonance imaging. Chem Rev 110(5):3019–3042
Torchilin P (2006) Micellar nanocarriers: pharmaceutical perspectives. Pharm Res 24(1):1
Torchilin VP, Frank-Kamenetsky MD, Wolf GL (1999) CT visualization of blood pool in rats by using long-circulating, iodine-containing micelles. Acad Radiol 6(1):61–65
Trubetskoy VS, Gazelle GS, Wolf GL, Torchilin VP (1997) Block-copolymer of polyethylene glycol and polylysine as a carrier of organic iodine: design of long-circulating particulate contrast medium for X-ray computed tomography. J Drug Target 4(6):381–388
Urvashi S, Dar MM, Hashmi AA (2014) Dendrimers: synthetic strategies, properties and applications. Orient J Chem 30(3):911–922
van Schooneveld MM et al (2010) A fluorescent, paramagnetic and PEGylated gold/silica nanoparticle for MRI, CT and fluorescence imaging. Contrast Media Mol Imaging 5(4):231–236
Varela-Moreira AA, Shi Y, Fens MHAM, Lammers T, Hennink WE, Schiffelers RM (2017) Clinical application of polymeric micelles for the treatment of cancer. Mater Chem Front 1(8):1485–1501
Vats S, Singh M, Siraj S, Singh H, Tandon S (2017) Role of nanotechnology in theranostics and personalized medicines. J Health Res Rev Wolters kluwer 4(1):1–7
Von Tappeiner H (1903) Therapeutische Versuche mit fluoreszierenden Stoffen. Munch Med Wochenschr 1:2042–2044
Wang YX, Hussain SM, Krestin GP (2001) Superparamagnetic iron oxide contrast agents: physicochemical characteristics and applications in MR imaging. Eur Radiol 11(11):2319–2331
Watermann A, Brieger J (2017) Mesoporous silica nanoparticles as drug delivery vehicles in cancer. Nanomaterials 7(7)
Wehrl F, Judenhofer MS, Wiehr S, Pichler BJ (2009) Pre-clinical PET/MR: technological advances and new perspectives in biomedical research. Eur J Nucl Med Mol Imaging 36(Suppl 1):S56–S68
Wishart DS (2016) Emerging applications of metabolomics in drug discovery and precision medicine. Nat Rev Drug Des Discov 15:473–484
Working K, Dayan AD (1996) Pharmacological-toxicological expert report. CAELYX. (stealth liposomal doxorubicin HCl). Hum Exp Toxicol 15(9):751–785
Wu SY, McMillan NAJ (2009) Lipidic systems for in vivo siRNA delivery. AAPS J 11(4):639–652
Wu P, Deng D, Gao J, Cai C (2016) Tubelike gold sphere-attapulgite nanocomposites with a high photothermal conversion ability in the near-infrared region for enhanced cancer photothermal therapy. ACS Appl Mater Interfaces 8(16):10243–10252
Wunder A et al (2003) Albumin-based drug delivery as novel therapeutic approach for rheumatoid arthritis. J Immunol (Baltim) 170(9):4793–4801
Xiao Q et al (2013) A core/satellite multifunctional nanotheranostic for in vivo imaging and tumor eradication by radiation/photothermal synergistic therapy. J Am Chem Soc 135(35):13041–13048
Xie T, Jing C, Long Y-T (2017) Single plasmonic nanoparticles as ultrasensitive sensors. Analyst 142(3):409–420
Xu H et al (2007) Preparation and preliminary evaluation of a biotin-targeted, lectin-targeted dendrimer-based probe for dual-modality magnetic resonance and fluorescence imaging. Bioconjug Chem 18(5):1474–1482
Yan X et al (2015) Optical and photoacoustic dual-modality imaging guided synergistic photodynamic/photothermal therapies. Nanoscale 7(6):2520–2526
Yang Y (2011) cRGD-functionalized, DOX-conjugated, and 64Cu-labeled superparamagnetic iron oxide nanoparticles for targeted anticancer drug delivery and PET/MR imaging. Biomaterials 32(17):4151–4160
Zhang M, Kievit FM (2011) Cancer nanotheranostics: improving imaging and therapy. Adv Healthc Mater Wiley 23:217–247
Zhang H et al (2015) Graphene oxide-BaGdF5 nanocomposites for multi-modal imaging and photothermal therapy. Biomaterials 42:66–77
Zheng J, Jaffray D, Allen C (2009) Quantitative CT imaging of the spatial and temporal distribution of liposomes in a rabbit tumor model. Mol Pharm 6(2):571–580
Zhou Z (2014) Iron/iron oxide core/shell nanoparticles for magnetic targeting MRI and near-infrared photothermal therapy. Biomaterials 35(26):7470–7478
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Suhag, D., Chauhan, M., Shakeel, A., Das, S. (2020). Emerging Trends in Nanotheranostics. In: Saxena, S., Khurana, S. (eds) NanoBioMedicine. Springer, Singapore. https://doi.org/10.1007/978-981-32-9898-9_14
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