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Anti-aging Effect of Ganoderma (Lingzhi) with Health and Fitness

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Ganoderma and Health

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 1182))

Abstract

Although Ganoderma (Lingzhi in Chinese) has been used as an elixir for thousands of years, its anti-aging effects still need to be clarified. Aging is related to immunoregulation, oxidation stress, and free radical product. Till now, Ganoderma exert life span elongation activities by inhibiting ROS production, lipid peroxidation, and advanced oxidation protein products; increasing production of mitochondrial electron transport complexes, SOD, CAT, GSH and GSH-Px, DPPH, and ABTS radical scavenger activities; and having immunomodulatory and antioxidant activity by increasing radical scavenging activity and ferric reducing antioxidant power. Ganoderma’s anti-aging effect on human remains a mystery, and its potential mechanisms underlying anti-aging effect for its clinical application still need to be elucidated.

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Authors and Affiliations

  1. Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, China

    Yan Pan & Zhibin Lin

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  1. Yan Pan
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  2. Zhibin Lin
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Correspondence to Zhibin Lin .

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Editors and Affiliations

  1. Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, China

    Zhibin Lin

  2. Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, China

    Baoxue Yang

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Pan, Y., Lin, Z. (2019). Anti-aging Effect of Ganoderma (Lingzhi) with Health and Fitness. In: Lin, Z., Yang, B. (eds) Ganoderma and Health. Advances in Experimental Medicine and Biology, vol 1182. Springer, Singapore. https://doi.org/10.1007/978-981-32-9421-9_13

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