Abstract
In this chapter, sensitivity and performance of graphene based surface plasmon resonance (G-SPR) optical bio-sensor is theoretically computed for measurement and detection of hemoglobin (Hb) concentration in human blood using nitride semiconductors (AlN, GaN and InN). Calculation is presented to get the performance for Gold (Au) and Silver (Ag) metals-on-graphene SPR configuration. Addition of aluminum nitride (AlN), gallium nitride (GaN) and indium nitride (InN) between (Au and Ag) metal and graphene layers enhanced overall performance of the biosensor. This study shows that (InN) is superior in contrast to AlN and GaN. This work can motivate for fabrication of a highly sensitive and accurate SPR biosensor to analyze Hb in human blood.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Similar content being viewed by others
References
N. Vajpayee, S.S. Graham, S. Bem, Basic examination of blood and bone marrow, in Henry’s Clinical Diagnosis and Management by Laboratory Methods, 22nd edn. ed. by R.A. McPherson M.R. Pincus (Saunders Elsevier, PA, 2011), pp. 510–534
P. Nestel, Anemia Detection Methods in Low-resource Settings: A Manual for Health Workers. Program for Appropriate Technology in Health (1997)
A. Shalabney, I. Abdulhalim, Electromagnetic fields distribution in multilayer thin film structures and the origin of sensitivity enhancement in surface plasmon resonance sensors. Sens. Actuators A Phys. 159(1), 24–32 (2010)
H. Raether, Surface Plasmons on Smooth and Rough Surfaces and on Gratings (Springer, Berlin, 1988)
Y. Wang, Q. Zhang, Y. Ren, L. Jing, T. Wei, Molecularly imprinted polymer thin film based surface plasmon resonance sensor to detect hemoglobin. Chem. Res. Chinese Univ. 30(1), 42–48 (2014)
K.S. Novoselov, V.I. Fal′ko, L. Colombo, P.R. Gellert, M.G. Schwab, K. Kim, A roadmap for graphene. Nature 490(7419), 192–200 (2012)
T. Kuila, S. Bose, P. Khanra, A.K. Mishra, N.H. Kim, J.H. Lee, Recent advances in graphene-based biosensors. Biosens. Bioelectron. 26(12), 4637–4648 (2011)
A.D. Boardman, Electromagnetic Surface Modes (Wiley, Chichester, 1982)
O. Zhernovaya, O. Sydoruk, V. Tuchin, A. Douplik, The refractive index of human hemoglobin in the visible range. Phys. Med. Biol. 56(13), 4013–4021 (2011)
M. Born, E. Wolf, Principles of Optics: Electromagnetic Theory of Propagation, Interference and Diffraction of Light (Pergamon Press, Oxford, 1964)
A. Zubrilov, M.E. Levinshtein, S.L. Rumyantsev, M.S. Shur, Properties of Advanced Semiconductor Materials GaN, AlN, InN, BN, SiC, SiGe (Wiley, New York, 2001)
Acknowledgements
Author BKS acknowledges financial support from SERB, Govt. of India (File: EMR/2016/001019).
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2020 Springer Nature Singapore Pte Ltd.
About this paper
Cite this paper
Mohanty, G., Sahoo, B.K. (2020). III–V Nitrides and Graphene SPR Biosensor for Hemoglobin Detection. In: Bhattacharya, I., Otani, Y., Lutz, P., Cherukulappurath, S. (eds) Progress in Optomechatronics. Springer Proceedings in Physics, vol 249. Springer, Singapore. https://doi.org/10.1007/978-981-15-6467-3_5
Download citation
DOI: https://doi.org/10.1007/978-981-15-6467-3_5
Published:
Publisher Name: Springer, Singapore
Print ISBN: 978-981-15-6466-6
Online ISBN: 978-981-15-6467-3
eBook Packages: Physics and AstronomyPhysics and Astronomy (R0)