Skip to main content

Retinal Arterial Macroaneurysm

  • Chapter
  • First Online:
Retinal Vascular Disease

Part of the book series: Retina Atlas ((RA))

  • 572 Accesses

Abstract

Retinal arterial macroaneurysm (RAM) was first published in a report by Loring in 1880 in which he described a bulging ectasia of the inferotemporal retinal artery in an asymptomatic healthy 25-year-old man (Loring 1880). Fernandez made the first association of retinal artery macroaneurysm with systemic hypertension in 1920 (Fernandez 1920). Robertson was the first to define retinal artery macroaneurysm as a distinct clinical entity and its natural history in 1973 (Robertson 1973). RAM most commonly affects women in their 60s and 70s and is associated with hypertension and atherosclerotic vessel disease. RAM is usually unilateral but may be bilateral in 10% of cases (Rabb et al. 1988). They are usually single but may be multiple in 20% of cases (Rabb et al. 1988).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Similar content being viewed by others

References

  • Amalric P, Dauban F, Courtois M, Broqua JP. Clinical symptoms and angiography of retinal artery macro-aneurysms. Bull Soc Ophthalmol Fr. 1979;79:109–11.

    CAS  Google Scholar 

  • Cho HJ, Rhee TK, Kim HS, et al. Intravitreal bevacizumab for symptomatic retinal arterial macroaneurysm. Am J Ophthalmol. 2013;155:898–904.

    Article  CAS  Google Scholar 

  • Dahreddine M, Eldirani H, Mutsinzi E, Hirsch A. Retinal arterial macroaneurysm complicated by premacular hemorrhage: treatment by YAG laser disruption. J Fr Ophthalmol. 2011;34(131):e1–5.

    Google Scholar 

  • Fichte C, Streeten BW, Friedman AH. A histopathologic study of retinal arterial aneurysms. Am J Ophthalmol. 1978;85:509–18.

    Article  CAS  Google Scholar 

  • Fernandez FM. Multiple aneurysms of the retinal arteries. Am J Ophthalmol. 1920;3:641–3.

    Article  Google Scholar 

  • Loring FB. Peculiar anatomical development of one of the central arteries of the retina. Trans Am Ophthalmol Soc. 1880;3:40–2.

    CAS  PubMed  PubMed Central  Google Scholar 

  • Mainster MA, Whitacre MM. Dye yellow photocoagulation of retinal arterial macroaneurysms. Am J Ophthalmol. 1988;105:97–8.

    Article  CAS  Google Scholar 

  • Mizutani T, Yasukawa T, Ito Y, et al. Pneumatic displacement of submacular hemorrhage with or without tissue plasminogen activator. Graefes Arch Clin Exp Ophthalmol. 2011;249:1153–7.

    Article  CAS  Google Scholar 

  • Nadel AJ, Gupta KK. Macroaneurysms of the retinal arteries. Arch Ophthalmol. 1976;94:1092–6.

    Article  CAS  Google Scholar 

  • Nakamura H, Hayakawa K, Sawaguchi S, Gaja T, Nagamine N, Medoruma K. Visual outcome after vitreous, sub-internal limiting membrane, and/or submacular hemorrhage removal associated with ruptured retinal arterial macroaneurysms. Graefes Arch Clin Exp Ophthalmol. 2008;246:661–9.

    Article  Google Scholar 

  • Pichi F, Morara M, Torrazza C, et al. Intravitreal bevacizumab for macular complications from retinal arterial macroaneurysms. Am J Ophthalmol. 2013;155:287–94. e1

    Google Scholar 

  • Rabb MF, Gagliano DA, Teske MP. Retinal arterial macroaneurysms. Surv Ophthalmol. 1988;33:73–96.

    Article  CAS  Google Scholar 

  • Robertson DM. Macroaneurysms of the retinal arteries. Trans Am Acad Ophthalmol Otolaryngol. 1973;77:OP55–67.

    CAS  PubMed  Google Scholar 

  • Schneider U, Wagner AL, Kreissig I. Indocyanine green videoangiography of hemorrhagic retinal arterial macroaneurysms. Ophthalmologica. 1997;211:115–8.

    Article  CAS  Google Scholar 

  • Townsend-Pico WA, Meyers SM, Lewis H. Indocyanine green angiography in the diagnosis of retinal arterial macroaneurysms associated with submacular and preretinal hemorrhages: a case series. Am J Ophthalmol. 2000;129:33–7.

    Article  CAS  Google Scholar 

  • Ulbig MW, Mangouritsas G, Rothbacher HH, Hamilton AM, McHugh JD. Long-term results after drainage of premacular subhyaloid hemorrhage into the vitreous with a pulsed Nd:YAG laser. Arch Ophthalmol. 1998;116:1465–9.

    Article  CAS  Google Scholar 

  • Wu TT, Chuang CT, Sheu SJ, Chiou YH. Non-vitrectomizing vitreous surgery for premacular haemorrhage. Acta Ophthalmol. 2011;89:194–7.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to J. Fernando Arevalo .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2020 Springer Nature Singapore Pte Ltd.

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Jiramongkolchai, K., Arevalo, J.F. (2020). Retinal Arterial Macroaneurysm. In: Sheyman, A., Fawzi, A.A. (eds) Retinal Vascular Disease. Retina Atlas. Springer, Singapore. https://doi.org/10.1007/978-981-15-4075-2_6

Download citation

  • DOI: https://doi.org/10.1007/978-981-15-4075-2_6

  • Published:

  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-15-4074-5

  • Online ISBN: 978-981-15-4075-2

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics