Abstract
Takayasu disease was first described by Dr. Mikito Takayasu, a Japanese ophthalmologist, in 1908 (Takayasu 1908). He described his findings in a 22-year-old woman with an absent radial artery pulse whose eyes had severe retinal vessel abnormalities; the retinal vessels branched 2–3 mm away from the disc, and the branches anastomosed to one another to create a wreath around the disc which was called wreath-like anastomosis (Fig. 10.1). Because the pulse of the radial artery was not palpable in patients with Takayasu disease, investigations have focused on the ischemic signs and symptoms of the upper body. In 1948, Shimizu and Sano investigated the etiology of Takayasu disease from clinical and pathological aspects, and called Takayasu disease a “pulseless disease” (Shimizu and Sano 1948, 1951). The arterial lumens, including that of the carotid and subclavian arteries, were either narrowed or obstructed due to inflammation at the aortic arch and at its branches, which caused the upper body to become ischemic (Fig. 10.2).
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Iwase, T., Terasaki, H. (2020). Takayasu Disease. In: Sheyman, A., Fawzi, A.A. (eds) Retinal Vascular Disease. Retina Atlas. Springer, Singapore. https://doi.org/10.1007/978-981-15-4075-2_10
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