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Role of Quorum Sensing in Microbial Infections and Biofilm Formation

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Model Organisms for Microbial Pathogenesis, Biofilm Formation and Antimicrobial Drug Discovery

Abstract

The infections and pathogenesis are continuously evolving processes to avoid the effects of hazardous situations and antibiotic susceptibility. In this process, the microbes could percept and conscientiousness towards its circumstances by their cellular and physiological mechanisms. All the bacterial populations can maintain phenotypes and genotype monitors in their competitive environment. To maintain all these community behaviors, the bacterial population utilize various natural signaling pathways under specific microbial language. The bacterial population was well regulated their extracellular or intercellular cooperative communication mechanisms known as quorum sensing. The quorum-sensing (QS) mechanism responds through small diffusible signal molecules; these signaling molecules were synthesized and secreted into intercellular or extracellular microenvironment at different phage of bacterial growth. However, we focus on this chapter microbial signal communications and also QS mechanisms in biofilm formation.

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Acknowledgments

The authors thank to DST-SERB-EMEQ-051/2014, Govt. of India for financial assistance. ER thanks to SERB for JRF fellowship and the research facilities supported by CU Kerala.

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  1. Department of Genomic Science, School of Biological Sciences, Central University of Kerala, Kasaragod, Kerala, India

    T. Eswara Rao & Ranjith Kumavath

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Correspondence to Ranjith Kumavath .

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  1. Department of Microbiology School of Life Sciences, Pondicherry University, Puducherry, India

    Busi Siddhardha

  2. Department of Biochemistry and Molecular Biology, School of Life Sciences, Pondicherry University, Puducherry, India

    Madhu Dyavaiah

  3. Botany and Microbiology Department, King Saud University, Riyadh, Saudi Arabia

    Asad Syed

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Eswara Rao, T., Kumavath, R. (2020). Role of Quorum Sensing in Microbial Infections and Biofilm Formation. In: Siddhardha, B., Dyavaiah, M., Syed, A. (eds) Model Organisms for Microbial Pathogenesis, Biofilm Formation and Antimicrobial Drug Discovery. Springer, Singapore. https://doi.org/10.1007/978-981-15-1695-5_5

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