Abstract
Systemic lupus erythematosus (SLE)/lupus continues to be the ten-headed monster posing challenges in diagnosis and management during all periods of life especially during pregnancy, when associated with a flare. The flare may be mild, moderate, or severe. Usually there would be at least consideration of a change or increase in treatment. Many disease activity indices are present, and some of them are used in pregnancy after suitable modifications. Lupus being a great masquerader has to be differentiated when it flares from other conditions which have been lucidly presented in tables in this chapter. The poor prognostic markers and pregnancy planning have been discussed. Management of different types and difficult flares have been dealt with for easy reading and understanding.
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References
Ruperto N, Hanrahan LM, Alacorn GS et al (2011) International consensus for a definition of disease flare in lupus. Lupus 20(5):453–462
Fortin P, Ferland D, Clarke A (1997) Activity and damage predicts later flares in lupus. Arthritis Rheum 40:S207
Fortin P, Ferland D, Moore A (1998) Rates and predictors of lupus flares. Arthrits Rheum 41:S218
Touma Z, Gladman D, Ibanez D et al (2011) Development and initial validation of the systemic lupus erythematosus disease activity index 2000 responder index 50. J Rheumatol 38(2):275–284
Pastore DEA, Costa D, Parpinelli MA, Surita FG (2018) A critical review on obstetric follow-up of women affected by systemic lupus erythematosus. Rev Bras Ginecol Obstet 40:209–224. https://doi.org/10.1055/s-0038-1625951
Ruiz-Irastorza G, Khamashta MA, Gordon C et al (2004) Measuring systemic lupus erythematosus activity during pregnancy: validation of the lupus activity index in pregnancy scale. Arthritis Rheum 51(1):78–82
Stojan G, Baer AN (2012) Flares of systemic lupus erythematosus during pregnancy and the puerperium: prevention, diagnosis and management. Expert Rev Clin Immunol 8(5):439–453
Rajeswari S (2018) Pregnancy in systemic lupus erythematosus. In: Chaturvedi V (ed) Manual of rheumatology, vol 39. CBS Publishers & Distributors Pvt Ltd, pp 363–365
Stanhope TJ et al (2012) Obstetric nephrology: lupus and lupus nephritis in pregnancy. Clin J Am Soc Nephrol 7:2089–2099
Rajeswari S (2018) Pregnancy in systemic lupus erythematosus. In: Chaturvedi V (ed) Manual of rheumatology, vol 39. CBS Publishers & Distributors Pvt Ltd, pp 365–366
Myers B (2012) Diagnosis and management of maternal thrombocytopenia in pregnancy. Br J Haematol 158:3–15
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Sankaralingam, R. (2020). Management of Lupus Flare During Pregnancy. In: Sharma, S. (eds) Women's Health in Autoimmune Diseases. Springer, Singapore. https://doi.org/10.1007/978-981-15-0114-2_12
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DOI: https://doi.org/10.1007/978-981-15-0114-2_12
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