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Genome-Wide Mapping of SNPs in Non-coding RNAs

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Non-coding RNAs in Complex Diseases

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 1094))

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Abstract

Non-coding RNAs (ncRNAs) are essential players that participate in multiple cellular processes. Cumulative evidence has linked ncRNA-related single nucleotide polymorphisms (SNPs) to various human diseases. However, the knowledge of ncRNA-related SNPs and their potential functional mechanisms in human disease need to be further discovered. Here, we reviewed related studies on functional SNPs in two main types of ncRNA, microRNAs (miRNAs) and long non-coding RNAs (lncRNAs), with a particular focus on these ncRNA-related SNPs as novel risk factor of disease etiology. These studies will gain global insights into the relationship between ncRNAs and their functions.

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Authors and Affiliations

  1. College of Bioinformatics Science and Technology, Harbin Medical University, Harbin, China

    Shangwei Ning & Yunpeng Zhang

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  1. Shangwei Ning
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  2. Yunpeng Zhang
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Correspondence to Shangwei Ning or Yunpeng Zhang .

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Editors and Affiliations

  1. College of Bioinformatics Science and Technology, Harbin Medical University, Harbin, Heilongjiang, China

    Xia Li

  2. College of Bioinformatics Science and Technology, Harbin Medical University, Harbin, China

    Juan Xu

  3. College of Bioinformatics Science and Technology, Harbin Medical University, Harbin, China

    Yun Xiao

  4. College of Bioinformatics Science and Technology, Harbin Medical University, Harbin, China

    Shangwei Ning

  5. College of Bioinformatics Science and Technology, Harbin Medical University, Harbin, China

    Yunpeng Zhang

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Ning, S., Zhang, Y. (2018). Genome-Wide Mapping of SNPs in Non-coding RNAs. In: Li, X., Xu, J., Xiao, Y., Ning, S., Zhang, Y. (eds) Non-coding RNAs in Complex Diseases. Advances in Experimental Medicine and Biology, vol 1094. Springer, Singapore. https://doi.org/10.1007/978-981-13-0719-5_5

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