Abstract
In normal pancreaticobiliary junction, the common bile duct and the main pancreatic duct penetrate the muscle layer of the duodenum obliquely and parallel to each other and make a junction in the submucosal layer just before opening into the duodenum. While in the case of pancreaticobiliary maljunction, the junction of the ducts is external of the muscle layer of the duodenum, thus forming an extension to the muscularis propria of the duodenum and thus forming an extended common channel. It is clarified that both the long common channel and narrowed duct segment in pancreaticobiliary maljunction originate from the pancreatic duct in ventral pancreas. In conclusion, pancreaticobiliary maljunction is an embryological disorder that the terminal bile duct join to the pancreatic duct in the ventral pancreas. This misconnection of both ducts occurs during the fifth week of gestation as the proximal portion of the hepatic diverticulum elongates and the ventral primordium has been carried away from the duodenum by elongation of the proximal part of the diverticulum.
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Hosomura, N., Fujii, H. (2018). Embryology of Pancreaticobiliary Maljunction. In: Kamisawa, T., Ando, H. (eds) Pancreaticobiliary Maljunction and Congenital Biliary Dilatation. Springer, Singapore. https://doi.org/10.1007/978-981-10-8654-0_2
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DOI: https://doi.org/10.1007/978-981-10-8654-0_2
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