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Enterohemorrhagic E. coli (EHEC): Environmental-Vehicle-Human Interface

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Zoonoses - Infections Affecting Humans and Animals

Abstract

Enterohemorrhagic Escherichia coli (EHEC) are a pathogenic subgroup of Shiga toxin-producing E. coli (STEC), and have demonstrated ability to cause severe intestinal disease and the hemolytic uremic syndrome (HUS). Cattle are the major reservoir of EHEC, where the bacteria can persist asymptomatically for years. Of particular concern are a small percentage of animals in herds that shed extremely high numbers of EHEC, termed ‘supershedders’, and are responsible for the majority of EHEC spread and contamination. Another transmission route is through the environment where EHEC can survive for weeks to many months, remaining viable in bovine feces, soil and water. EHEC contamination of meat during slaughter or processing, or contamination of plants via EHEC-containing water or manure are major routes of entry into the food chain. Several hundred outbreaks caused by EHEC O157 as well as non-O157 strains have been identified in industrialized countries worldwide. Current and future research efforts are focused on rapid outbreak identification, development of therapeutics, and implementation of preventative measures.

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Authors and Affiliations

  1. Institute of Hygiene, University Hospital of Münster, Robert-Koch-Str. 41, 48149, Münster, Germany

    Helge Karch Biol

  2. Institute of Hygiene, University Hospital of Münster, Münster, Germany

    Shana R. Leopold, Annelene Kossow, Alexander Mellmann, Robin Köck & Andreas Bauwens

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  1. Helge Karch Biol
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  2. Shana R. Leopold
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  1. Dept. of Infectiology, Bavarian Health and Food Safety Authority, Oberschleißheim, Bayern, Germany

    Andreas Sing

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Karch, H., Leopold, S., Kossow, A., Mellmann, A., Köck, R., Bauwens, A. (2015). Enterohemorrhagic E. coli (EHEC): Environmental-Vehicle-Human Interface. In: Sing, A. (eds) Zoonoses - Infections Affecting Humans and Animals. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-9457-2_9

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