Abstract
Fumagillin is an antibiotic produced by the parasitic fungus, Aspergillus fumigatus, and acts by inhibiting RNA synthesis. It is acidic and is normally presented as the dicyclohexylamine (DCH) ((C6H11)2NH) salt. This salt is sparingly soluble in water but moderately soluble in ethanol.
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El-Matbouli, M. and Hoffmann, R.W. (1991) Prevention of experimentally induced whirling disease in rainbow trout Oncorhynchus mykiss by fumagillin. Diseases of Aquatic Organisms 10, 109–113.
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Higgins, M.J. and Kent, M.L. (1996) Field trials with fumagillin for the control of proliferative kidney disease in coho salmon. Progressive Fish-Culturist 58, 268–272.
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Molnar, K., Baska, F. and Szekely, C. (1987) Fumagillin, an efficacious drug against renal sphaerosporosis of the common carp Cyprinus carpio. Diseases of Aquatic Organisms 2, 187–190.
Rapp, J. (1995) Treatment of rainbow trout (Oncorhynchus mykiss Walb.) fry infected with Ichthyophthirius (Ichthyophthirius multifiliis) by oral administration of dimetridazole. Bulletin of the European Association of Fish Pathologists 15, 67–69.
Wishkovski, A., Groff, J.M., Lauren, D.J., Toth, R.J. and Hedrick, R.P. (1990) Efficacy of fumagillin against proliferative kidney disease and its toxic side effects in rainbow trout (Oncorhynchus mykiss) fingerlings. Fish Pathology 25, 141–146.
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© 2000 Springer Science+Business Media Dordrecht
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Treves-Brown, K.M. (2000). Systemic Anti-Protozoal Agents. In: Applied Fish Pharmacology. Aquaculture, vol 3. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-0761-9_12
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DOI: https://doi.org/10.1007/978-94-017-0761-9_12
Publisher Name: Springer, Dordrecht
Print ISBN: 978-90-481-4014-5
Online ISBN: 978-94-017-0761-9
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