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Chemistry and Bioactivity of Saponins from Some Sri Lankan Plants

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Saponins in Food, Feedstuffs and Medicinal Plants

Part of the book series: Proceedings of the Phythochemical Society of Europe ((PPSE,volume 45))

Abstract

The flora of Sri Lanka comprises about 3500 flowering plants of which about 850 species are endemic to the island [1]. Of these 3500 species, about 750 are claimed to have uses in the indigenous system of medicine [2]. In a continuation of our studies towards the discovery of biologically active saponins from Sri Lankan plants, we have chemically investigated Diploclisia glaucescens and Anamirta cocculus (Menispermaceae), Pometia eximia and Filicium decipiens (Sapindaceae), Terminalia catappa (Combretaceae) and Uncaria elliptica (Rubiaceae). Chemical investigation of the methanol extracts of these plants led to the isolation of over twenty five saponins. Of them fifteen triterpenoidal saponins were found to be new natural products. Some of them showed insecticidal, anti-inflammatory and strong molluscicidal activity.

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References

  1. Bandaranayake, W. M., Sultanbawa, M. U. S., Weerasekera, S. C. and Balasubramanim, S. (1974) A glossary of sinhala and tamil names of the plants of Sri Lanka, The Sri Lanka Forester XI, 67.

    Google Scholar 

  2. Abeywickrama, B. A. (1975) Proc. Workshop on Natural Products, Colombo, Sri Lanka.

    Google Scholar 

  3. Chopra, R. N., Nayar, S. L. and Chopra, I. C. (1956) Glossary of Indian Medicinal Plants, pp72 and 99 Council of Scientific and Industrial Research, New Delhi.

    Google Scholar 

  4. Sultanbawa, M. U. S., Wannigama, G. P., Bandaranayake, W. M., Kumar, V., Gunatilaka, A. A. L., Marikkar, F. A., Balasubramaniam, S. and Arsecularatne, S. N. (1978) Chemical investigation of Ceylonese Plants. Part XXIX. A survey of plants of Sri Lanka (Ceylon) for alkaloids I, Lloydia 41, 597.

    Google Scholar 

  5. Miller, R. W., Clardy, J., Kozlowski, J., Mikolajczak, K. L., Plattner, R. D., Powell, R. G., Smith, C. R., Weisleder, D. and Qi-Tai, Z. (1985) Phytoecdysteroids of Diploclisia glaucescens seed, Planta Medica 51, 40–42.

    Article  CAS  Google Scholar 

  6. Shah, V.C., D’Sa, A. S. and de Souza, N. J. (1989) Chonemorphine, stigmasterol and ecdysterone: Steroids isolated through bioassay-directed plant screening programs, Steroids 53, 559–565.

    Article  CAS  Google Scholar 

  7. Bandara, B. M. R., Jayasinghe, L., Karunaratne, V., Wannigama, G. P., Bokel, M., Kraus, W. and Sotheeswaran, S. (1989) Ecdysterone from stem of Diploclisia glaucescens 28, 1073–1075.

    CAS  Google Scholar 

  8. Bandara, B. M. R., Jayasinghe, U. L. B., Karunaratne, V., Wannigama, G. P., Bokel, M. and Sotheeswaran, S. (1990) Triterpenoidal constituents of Diploclisia glaucescens, Planta Medica 56, 290–292.

    Article  CAS  Google Scholar 

  9. Bandara, B. M. R., Jayasinghe, L., Karunaratne, V., Wannigama, G. P., Kraus, W., Bokel, M. and Sotheeswaran, S. (1989) Diploclisin, a bidesmosidic triterpenoid saponin from Diploclisia glaucescens, Phytochemistry 28, 2783–2785.

    Article  CAS  Google Scholar 

  10. Jayasinghe, U. L. B. (1995) Pilot plant scale extraction of ecdysterone from Diploclisia glaucescens, ACGC Chemical Research Communications 3, 38–39.

    CAS  Google Scholar 

  11. Jayasinghe, U. L. B., Wannigama, G. P. and MacLeod, J. K. (1993) Saponins of Diploclisia glaucescens. Natural Product Letters 2, 249–253.

    Article  CAS  Google Scholar 

  12. Jayasinghe, U. L. B., Wannigama, G. P. and MacLeod, J. K. (1998) Glucuronides of Diploclisia glaucescens, Journal of the Chemical Society of Pakistan 20, 131–137.

    CAS  Google Scholar 

  13. Hegnauer, R. (1969) Chemotaxonomie de Pflanzen, 5, p 73, Birkhäuser Verlag, Basel, Stuttgart.

    Book  Google Scholar 

  14. Jayaweera, D. M. A. (1981) Medicinal plants used in Sri Lanka Part I V, The National Science Council, Sri Lanka.

    Google Scholar 

  15. Jayasinghe, L., Wannigama, G. P. and MacLeod, J. K. (1993) Triterpenoids of Anamirta cocculus, Phytochemistry 34, 1111–1116.

    Article  CAS  Google Scholar 

  16. Jayasinghe, U. L. B., Wannigama, G. P., Balasubramaniam, S., Nasir, H. and Atta-ur-Rahman (1992) Benzylisoquinoline Alkaloids from Anamirta cocculus and Diploclisia glaucescens Journal of the National Science Council of Sri Lanka 20, 187–190.

    CAS  Google Scholar 

  17. Jayasinghe, U. L. B. (1992) Ph. D. Thesis, University of Peradeniya, Sri Lanka.

    Google Scholar 

  18. Hotta, M., Ogata, K., Nitta, A., Hoshikawa, K., Yanagi, M. and Yamazaki, K. eds. (1989) Useful plants of the world, Heibonsha Ltd, Tokyo.

    Google Scholar 

  19. Wijesinghe, Y. (1994) Check list of woody perenial plants of Sri Lanka, p 35, Sri Lanka Forestry Department, Forestry Information Service.

    Google Scholar 

  20. Hostettmann, K., Kizu, H. and Tomimori, T. (1982) Molluscicidal properties of various saponins, Planta Medica 44, 34–35.

    Article  CAS  Google Scholar 

  21. Maillard, M., Marston, A. and Hostettmann, K. (1993) Search for molluscicidal and larvicidal agents from plants. ACS Symposium series, 534, 256–273.

    Article  CAS  Google Scholar 

  22. Jayasinghe, L., Shimada, H., Hara, N. and Fujimoto, Y. (1995) Hederagenin glycosides from Pometia eximia. Phytochemistry 40, 891–897.

    Article  CAS  Google Scholar 

  23. Jayasinghe, U. L. B., Fujimoto, Y. and Hostettmann, K. (1998) Molluscicidal saponins from Pometia eximia, Natural Products Letters 12, 135–138.

    Article  CAS  Google Scholar 

  24. Jayasinghe, U. L. B. and Fujimoto, Y. (1999) Insecticidal saponins from Pometia eximia. Fitoterapia 70, 87–88.

    Article  CAS  Google Scholar 

  25. Jayasinghe, U. L. B., Bandara, A. G. D. and Fujimoto, Y, 1999, manuscript in preparation.

    Google Scholar 

  26. Hooker, J. D. (1879) Flora of British India, II, p 444, L. Reeve & Co. Ltd.

    Google Scholar 

  27. Diyabalanage,T. K. K., Jayasinghe, U. L. B., Simmonds, P. M., Wannigama, G. P. and Wickramasinghe, A. (1997) Chemical investigation of Terminalia catappa, ACGC Chemical Research Communications 6, 26–28.

    Google Scholar 

  28. Diyabalanage, T. K. K., Kumarihamy, B. M. M., Wannigama, G. P., Jayasinghe, L., Merlini, L. and Scaglioni, L. (1997) Alkaloids of Uncaria elliptica, Phytochemistry 45, 1731–1732.

    Article  CAS  Google Scholar 

  29. Diyabalanage, T. K. K., Jayasinghe, U. L. B., Simmonds, P. M. and Wannigama, G. P. (1997) A quinovic acid glycoside from Uncaria elliptica, ACGC Chemical Research Communications, 6, 29–32.

    CAS  Google Scholar 

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Author information

Authors and Affiliations

  1. Institute of Fundamental Studies, Hantana Road, Kandy, Sri Lanka

    U. L. B. Jayasinghe

  2. Department of Chemistry, University of Peradeniya, Peradeniya, Sri Lanka

    G. P. Wannigama

  3. Department of Chemistry, Tokyo Institute of Technology, Tokyo 152, Japan

    Y. Fujimoto

Authors
  1. U. L. B. Jayasinghe
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  2. G. P. Wannigama
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  3. Y. Fujimoto
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Editor information

Editors and Affiliations

  1. Institute of Soil Science and Plant Cultivation, Pulawy, Poland

    Wieslaw Oleszek

  2. University of Lausanne, Lausanne, Switzerland

    Andrew Marston

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Jayasinghe, U.L.B., Wannigama, G.P., Fujimoto, Y. (2000). Chemistry and Bioactivity of Saponins from Some Sri Lankan Plants. In: Oleszek, W., Marston, A. (eds) Saponins in Food, Feedstuffs and Medicinal Plants. Proceedings of the Phythochemical Society of Europe, vol 45. Springer, Dordrecht. https://doi.org/10.1007/978-94-015-9339-7_12

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  • DOI: https://doi.org/10.1007/978-94-015-9339-7_12

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-90-481-5341-1

  • Online ISBN: 978-94-015-9339-7

  • eBook Packages: Springer Book Archive

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