Abstract
The binary complexes of transition metal ions with dipeptides or nucleobases have already been well-characterized and the most important findings were rewieved by several authors [1, 2]. In case of oligopeptides the metal binding ability of the ligands depends on the the involvement of amide nitrogens and side chain residues in metal ion coordination. Copper(II) and palladium(II) were reported to be the most effective to induce deprotonation and coordination of amide nitrogens and, as a consequence, these metal ions form especially stable complexes with dipeptides.
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References
Sövagö, I. (1990) Coordination Chemistry of Peptides, in “Biocoordination Chemistry”, ed. Burger, K., Ellis Horwood, New York
Lönnberg, H. (1990) Proton and Metal Ion Interaction with Nucleic Acid Bases, in “Biocoordination Chemistry”, ed. Burger, K., Ellis Horwood, New York
Scheller, K.H., S-Krattiger, V. and Martin, R.B. (1981) Equilibria in solutions of nucleosides, 5′-nucleotides and dienPd2+, J. Amer. Che. Soc., 103, 6833–6839.
Kozlowski, H. and Matczak-Ion, E. (1979) Proton and Carbon-13 NMR studies on coordination of ATP nucleotide to Pd(II)glycyl-L-histidine complex, Inorg. Chim. Acta, 32, 143–148.
Wienken, M., Zangrando, E., Randaccio, L., Menzer, S. and Lippert B. (1993) Structural and solution study on binary peptide and ternary peptide-nucleobase complexes of palladium(II), J. Chem. Soc. Dalton Trans., 3349–3357.
Kim, S.H. and Martin R.B. (1984) Stabilities and 1H NMR studies of (diethylenetriamine)Pd(II) with nucleosides and related ligands, Inorg. Chim. Acta, 91, 11–18.
Sugimori, T., Shibakawa, K., Masuda, H., Odani, A. and Yamauchi, O. (1993) Ternary metal complexes with tyrosine containing dipeptides, Inorg. Chem., 32, 4951–4959.
Appleton, T.G., Pesch, F.J., Wienken, M., Menzer S. and Lippert, B. (1992) Linkage isomerism in square-planar complexes of platinum and palladium with histidine and derivatives, Inorg. Chem., 31, 4410–4419.
Kasselouri, S., Garoufis, A., Lamera-Hadjiliadis, M. and Hadjiliadis, N. (1990) Binary complexes of palladium(II) with peptides and ternary complexes of palladium(II) with peptides and nucleosides-nucleotides, Coord. Chem. Rev., 104, 1–12.
Sövagö, I. Kiss, A. and Lippert B. (1995) Spectroscopic and potentiometric studies on the ineraction of trans-[(MeNH2)2Pt(mcyt)2PdCl]NO3 with derivatives of amino acids, J. Chem. Soc. Dalton Trans., 489–494.
Sövagö, I., Kiss, A., Farkas, E., Sanna, D., Marras, P. and Micera, G. (1996) Potentiometric and spectroscopic studies on the ternary complexes of copper(II) with dipeptides and nucleobases, J. Inorg. Biochem., (in press).
Krumm, M., Zangrando, E., Randaccio, E., Menzer, S. and Lippert, B. (1993) Strong metal-metal bonds between trans-(amine)2PtII and-PdII in heteronuclear complexes of cytosine nucleobases, Inorg. Chem., 32, 700–712.
Martin, R.B. and Mariam, Y.H. (1979) Interaction between metal ions and nucleic bases, nucleosides and nucleotides in solution, Metal Ions in Biological Systems, 9, 57–124.
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© 1997 Springer Science+Business Media Dordrecht
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Sóvágó, I., Kiss, A., Farkas, E., Lippert, B. (1997). Potentiometric and Spectroscopic Studies on the Ternary Complexes of Copper(II) and Palladium(II) with Peptides and Nucleobases. In: Hadjiliadis, N.D. (eds) Cytotoxic, Mutagenic and Carcinogenic Potential of Heavy Metals Related to Human Environment. NATO ASI Series, vol 26. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-5780-3_33
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DOI: https://doi.org/10.1007/978-94-011-5780-3_33
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