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Design of Proteins with ATCUN Motif which Specifically Cleave DNA

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Cytotoxic, Mutagenic and Carcinogenic Potential of Heavy Metals Related to Human Environment

Part of the book series: NATO ASI Series ((ASEN2,volume 26))

Abstract

The design of proteins for sequence specific cleavage of DNA can potentially serve a number of uses such as the creation of artificial restriction endonucleases. Such artificial endonucleases would be extremely useful in genomic mapping and also to chemically excise aberrant DNA sequences.

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Author information

Authors and Affiliations

  1. Department of Biochemistry Research, The Hospital for Sick Children, Toronto, Ontario, M5G 1X8, Canada

    B. Sarkar

  2. Department of Biochemistry, University of Toronto, Toronto, Ontario, M5S 1A8, Canada

    B. Sarkar

Authors
  1. B. Sarkar
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Editor information

Editors and Affiliations

  1. Laboratory of Inorganic and General Chemistry, Department of Chemistry, University of Ioannina, Ioannina, Greece

    Nick D. Hadjiliadis

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© 1997 Springer Science+Business Media Dordrecht

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Sarkar, B. (1997). Design of Proteins with ATCUN Motif which Specifically Cleave DNA. In: Hadjiliadis, N.D. (eds) Cytotoxic, Mutagenic and Carcinogenic Potential of Heavy Metals Related to Human Environment. NATO ASI Series, vol 26. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-5780-3_30

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  • DOI: https://doi.org/10.1007/978-94-011-5780-3_30

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-6440-8

  • Online ISBN: 978-94-011-5780-3

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