Abstract
Lithium salts have been clinically used, for more than forty years, in the treatment of manic-depression or bipolar disease, as well as in other psychiatric and non-psychiatric disorders, such as depression, schizophrenia, hyperthyroidism, conditions caused by the Herpes simplex and AIDS virus and low blood cells counts associated with chemotherapy [1, 2]. In spite of the well recognized therapeutic effectiveness of lithium, the mechanism of action at the molecular and cellular level of the active species – the lithium ion, Li+ – is still unclear.
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Castro, M.M.C.A., Nikolakopoulos, J., Zachariah, C., de Freitas, D.M., Geraldes, C.F.G.C., Ramasamy, R. (1997). Li+ Transport Properties in Perfused Neuronal Cells by 7Li NMR Spectroscopy. In: Hadjiliadis, N.D. (eds) Cytotoxic, Mutagenic and Carcinogenic Potential of Heavy Metals Related to Human Environment. NATO ASI Series, vol 26. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-5780-3_18
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DOI: https://doi.org/10.1007/978-94-011-5780-3_18
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