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Clinical Implications of Changes in Lens and Ocular Imaging Properties

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Basic and Clinical Applications of Vision Science

Part of the book series: Documenta Ophthalmologica Proceedings Series ((DOPS,volume 60))

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Abstract

Our measurements of in vitro changes in the focal properties of the human crystalline lens as a function of accommodative state and age demonstrate that presbyopia is a lens based phenomenon and that there may be a lens mediated drift towards a more hyperopic refractive state with ageing. The blur of the image formed by the lens changes as a function of age and accommodative state. Ocular image quality varies with accommodative state and pupil size. Although changes in ocular image quality with accommodative state are analogous to lens changes, there are qualitative differences between lens and ocular image quality. Asymmetric ocular image quality, mediated in part by tilt and decentration of the optical elements, combines with symmetrical blur to influence all methods of retinal imaging. Confocal scanning laser ophthalmoscopy (CSLO) is degraded least by retinal blur followed by scanning laser ophthalmoscopy (SLO) and lastly by conventional fundus imaging. Optimisation of ocular image quality through the choice of pupil centration, has produced the first real-time videoimages of the human cones. These results also have clinical implications to the development of refractive error and to the design of refractive corrections.

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Author information

Authors and Affiliations

  1. School of Optometry, University of Waterloo, Waterloo, Canada

    Melanie C. W. Campbell, Adrian Glasser & Austin Roorda

Authors
  1. Melanie C. W. Campbell
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  2. Adrian Glasser
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  3. Austin Roorda
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Editors and Affiliations

  1. School of Optometry and Department of Physics and Astronomy, St. Louis, Miss., USA

    V. Lakshminarayanan

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© 1997 Springer Science+Business Media Dordrecht

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Campbell, M.C.W., Glasser, A., Roorda, A. (1997). Clinical Implications of Changes in Lens and Ocular Imaging Properties. In: Lakshminarayanan, V. (eds) Basic and Clinical Applications of Vision Science. Documenta Ophthalmologica Proceedings Series, vol 60. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-5698-1_10

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  • DOI: https://doi.org/10.1007/978-94-011-5698-1_10

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-6403-3

  • Online ISBN: 978-94-011-5698-1

  • eBook Packages: Springer Book Archive

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