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Changes in intracellular signaling following Helicobacter pylori infection of gastric epithelial cells

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Helicobacter pylori

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Abstract

Many microbial pathogens exploit host cell signalling during infection of humans’. This manipulation of eukaryotic cell signal transduction pathways is likely to play a role in disease pathogenesis. Current research suggests that the gastric pathogen Helicobacter pylori also utilizes host signal transduction pathways during infection. The ability of these pathogens to manipulate host signalling also allows investigators to use the microbes as a probe to answer enigmatic questions regarding cellular functions. This area of research has recently been termed ‘cellular microbiology’ and is yielding important new information relevant to cell biology2. Furthermore, an understanding of bacterial pathogen—host cell interactions should enhance our understanding of disease pathophysiology and thereby lead to the development of novel therapeutic agents.

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Authors
  1. N. L. Jones
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  2. P. M. Sherman
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Editor information

Editors and Affiliations

  1. Division of Gastroenterology, McMaster University Medical Centre, 1200 Main Street West, Hamilton, Ontario, L8N 3Z5, Canada

    Richard H. Hunt (Professor of Medicine, Director) (Professor of Medicine, Director)

  2. Department of Gastroenterology and Hepatology, Academic Medical Centre, 9 Meibergdreef, 1105 AZ, Amsterdam, The Netherlands

    Guido N. J. Tytgat (Professor) (Professor)

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© 1998 Springer Science+Business Media Dordrecht

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Jones, N.L., Sherman, P.M. (1998). Changes in intracellular signaling following Helicobacter pylori infection of gastric epithelial cells. In: Hunt, R.H., Tytgat, G.N.J. (eds) Helicobacter pylori. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-4882-5_11

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  • DOI: https://doi.org/10.1007/978-94-011-4882-5_11

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-6046-2

  • Online ISBN: 978-94-011-4882-5

  • eBook Packages: Springer Book Archive

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