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Quantitative approaches to the analysis of the control and regulation of microbial metabolism

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Quantitative Aspects of Growth and Metabolism of Microorganisms

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Abstract

Recently, a number of novel ways of considering the control, regulation and thermodynamics of microbial physiology have been developed and applied. We here present an overview of the new concepts involved, of their limitations and of the most recent attempts to deal with those limitations. We conclude that there no longer exist reasons of principle for vagueness in discussions of the control of microbial physiology and energetics. Further, the novel conceptual methods serve to remove part of the discordance between holistic and reductionistic views of microbial physiology.

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Authors and Affiliations

  1. Division of Molecular Biology, The Netherlands Cancer Institute, Plesmanlaan 121, NL-1066 CX, Amsterdam, Netherlands

    Hans V. Westerhoff, Wally van Heeswijk & Daniel Kahn

  2. E. C. Slater Institute for Biochemical Research, University of Amsterdam, Plantage Muidergracht 12, NL-1018 TV, Amsterdam, The Netherlands

    Hans V. Westerhoff & Wally van Heeswijk

  3. Department of Biological Sciences, University College of Wales, Aberystwyth, Dyfed, SY23 3DA, UK

    Douglas B. Kell

Authors
  1. Hans V. Westerhoff
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  2. Wally van Heeswijk
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  3. Daniel Kahn
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  4. Douglas B. Kell
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Editor information

Editors and Affiliations

  1. Biological Laboratory, Free University of Amsterdam, The Netherlands

    A. H. Stouthamer

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© 1992 Springer Science+Business Media Dordrecht

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Westerhoff, H.V., van Heeswijk, W., Kahn, D., Kell, D.B. (1992). Quantitative approaches to the analysis of the control and regulation of microbial metabolism. In: Stouthamer, A.H. (eds) Quantitative Aspects of Growth and Metabolism of Microorganisms. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-2446-1_6

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  • DOI: https://doi.org/10.1007/978-94-011-2446-1_6

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-5079-1

  • Online ISBN: 978-94-011-2446-1

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