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The molecular biology of the transmissible dementias

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Molecular and Cell Biology of Neuropsychiatric Diseases

Part of the book series: Molecular and Cell Biology of Human Diseases Series ((Mol. Cell Biol. Hu. Dis.))

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Abstract

Over the last few years it has become increasingly obvious that the prion protein (PrP) plays a significant role in the aetiology of Creutzfeldt-Jakob disease (CJD), Gerstmann-Sträussler-Scheinker syndrome (GSS) and kuru and in similar neurodegenerative diseases in animals, e.g. scrapie in sheep, transmissible mink encephalopathy and more recently bovine spongiform encephalopathy (BSE) in cattle. This has led Westaway and colleagues (1989) to suggest that all these diseases, in animals and man, should be described as prion diseases.

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  1. Frank Owen
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  1. Department of Physiology, University of Manchester, UK

    Frank Owen

  2. Department of Optometry and Vision Sciences, UMIST, UK

    Ruth Itzhaki

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Owen, F. (1994). The molecular biology of the transmissible dementias. In: Owen, F., Itzhaki, R. (eds) Molecular and Cell Biology of Neuropsychiatric Diseases. Molecular and Cell Biology of Human Diseases Series. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-0709-9_5

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  • DOI: https://doi.org/10.1007/978-94-011-0709-9_5

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-4305-2

  • Online ISBN: 978-94-011-0709-9

  • eBook Packages: Springer Book Archive

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