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(ULTRA)2-High Throughput Genetic Analysis Using Microfabricated Capillary Array Electrophoresis Devices

  • Conference paper
Micro Total Analysis Systems 2001

Abstract

We have developed technologies enabling the next generation in high-throughput electrophoretic genotyping using our rotary confocal scanner. The capabilities of this system are illustrated by (i) a short tandem repeat (STR) DNA genotyping separation performed on a 150-mm diameter, radial 96-lane µCAE microplate in less than 8 minutes, and (ii) the parallel assay of the common H63D mutation in the human HFE gene on a 384-lane, 200-mm diameter microplate in only 7 minutes.

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Author information

Authors and Affiliations

  1. Department of Chemistry, University of California, Berkeley, CA, 94720

    Charles A. Emrich, Igor L. Medintz, Huijun Tian, Lorenzo Berti & Richard A. Mathies

  2. Department of Biophysics, University of California, Berkeley, CA, 94720

    Charles A. Emrich

Authors
  1. Charles A. Emrich
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  2. Igor L. Medintz
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  3. Huijun Tian
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  4. Lorenzo Berti
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  5. Richard A. Mathies
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Editor information

Editors and Affiliations

  1. Oak Ridge National Laboratory, Oak Ridge, Tennessee, USA

    J. Michael Ramsey

  2. MESA+ Research Institute, University of Twente, Enschede, The Netherlands

    Albert van den Berg

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© 2001 Springer Science+Business Media New York

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Emrich, C.A., Medintz, I.L., Tian, H., Berti, L., Mathies, R.A. (2001). (ULTRA)2-High Throughput Genetic Analysis Using Microfabricated Capillary Array Electrophoresis Devices. In: Ramsey, J.M., van den Berg, A. (eds) Micro Total Analysis Systems 2001. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-1015-3_5

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  • DOI: https://doi.org/10.1007/978-94-010-1015-3_5

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-3893-5

  • Online ISBN: 978-94-010-1015-3

  • eBook Packages: Springer Book Archive

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