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Metastasis to the Central Nervous System

  • Chapter
Metastasis / Dissemination

Part of the book series: Cancer Growth and Progression ((CAGP,volume 8))

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Abstract

Metastasis to the central nervous system (CNS) is both a common clinical problem and a fascinating biological phenomenon. Metastasis to the CNS is also a devastating complication of cancer. Few symptoms are more disabling and frightening to patients and their families than neurological ones (eg., convulsions, dementia, aphasia, paralysis, incontinence). Adrenocorticosteroid hormones, radiation therapy and in selected patients, surgery, are the principle treatment modalities. With prompt diagnosis and appropriate management neurological symptoms and signs resolve or improve in many patients. Neurological improvement is often maintained until death from progressive systemic tumor. However, all too often, death and severe disability are directly or indirectly attributable to CNS metastasis.

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Authors
  1. Douglas W. Zochodne
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  2. J. Gregory Cairncross
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Editor information

Editors and Affiliations

  1. Pittsburgh Cancer Institute, Pittsburgh, Pa, USA

    Elizier L. Gorelik

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© 1989 Kluwer Academic Publishers, Dordrecht

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Zochodne, D.W., Cairncross, J.G. (1989). Metastasis to the Central Nervous System. In: Gorelik, E.L. (eds) Metastasis / Dissemination. Cancer Growth and Progression, vol 8. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-2534-2_3

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  • DOI: https://doi.org/10.1007/978-94-009-2534-2_3

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-7645-6

  • Online ISBN: 978-94-009-2534-2

  • eBook Packages: Springer Book Archive

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