Abstract
The role of steroid hormones in the development of adenocarcinoma of the breast is not well understood. As breast cancer rarely occurs in the undeveloped breast, it is at least clear that these hormones are necessary for the development of breast cancer insofar as they are necessary for mammary gland growth. The presence of estrogens and progesterone serves to prepare the background for the action of genetic factors, viruses and chemicals in the initiation of malignancy. Once initiated, many breast tumors remain under hormonal control. This chapter will review the current understanding of the role of steroid hormones in the epidemiology, biology and treatment of breast cancer.
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LeMaistre, C.F., McGuire, W.L. (1989). Hormone Dependent Breast Cancer. In: Levine, A.S. (eds) Etiology of Cancer in Man. Cancer Growth and Progression, vol 6. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-2532-8_9
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