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Genetic Evaluation of Ontologically Related Neural Crest Tumors

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Etiology of Cancer in Man

Part of the book series: Cancer Growth and Progression ((CAGP,volume 6))

Abstract

During the last decade, advances in cell biology have provided important insights and research techniques which neurobiologists have successfully exploited to enhance our understanding of neuronal cell differentiation and function. These studies have led to the characterization of neuronal cell surface markers, biochemical profiles, and unique ultra-structural features that have set the stage for genetic studies of the molecular mechanisms underlying the malignant behavior of tumors of closely related tissues arising from the embryonic neural crest. The neuronal tumors of this group present a unique opportunity for the elucidation of events critical in tumor development since they arise in a tissue considered to be terminally differentiated and thus composed of non-dividing cells.

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Authors
  1. Catherine McKeon
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  2. Carol J. Thiele
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  3. Timothy J. Triche
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  4. Mark A. Israel
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Editor information

Editors and Affiliations

  1. National Institutes of Child Health & Human Development, National Institutes of Health, Bethesda, Md., USA

    Arthur S. Levine

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© 1989 Kluwer Academic Publishers, Dordrecht

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McKeon, C., Thiele, C.J., Triche, T.J., Israel, M.A. (1989). Genetic Evaluation of Ontologically Related Neural Crest Tumors. In: Levine, A.S. (eds) Etiology of Cancer in Man. Cancer Growth and Progression, vol 6. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-2532-8_4

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  • DOI: https://doi.org/10.1007/978-94-009-2532-8_4

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-7644-9

  • Online ISBN: 978-94-009-2532-8

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