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Genetic Diseases, Hamartomas, and Familial Occurrence of Neoplasms

  • Chapter
Etiology of Cancer in Man

Part of the book series: Cancer Growth and Progression ((CAGP,volume 6))

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Abstract

Most malignant neoplasms likely arise from the deleterious effects of environmental carcinogens. In addition, it appears that genetic predisposition or resistance governs responses of individuals to these agents. This interaction between environmental carcinogens and genetic factors has been termed ecogenetics. Ultimately, the final step in the genesis of malignant neoplasms involves molecular and/or cytogenetic alterations that free the cell from internal or external host regulatory control.

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Purtilo, D.T., Linder, J., Manolov, G., Manolova, Y. (1989). Genetic Diseases, Hamartomas, and Familial Occurrence of Neoplasms. In: Levine, A.S. (eds) Etiology of Cancer in Man. Cancer Growth and Progression, vol 6. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-2532-8_3

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  • DOI: https://doi.org/10.1007/978-94-009-2532-8_3

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