Abstract
The term “apolipoproteins” was initially coined by John Oncley in the 1940s to refer to the protein constituents of the plasma lipoproteins. Since then, we have learned a great deal about the structures, functions, and in some cases, the mechanisms of apolipoproteins.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Similar content being viewed by others
References
Segrest JP, Jackson RL, Morrisett JD, Gotto AM, Jr. A molecular theory of lipid-protein interactions in the plasma lipoproteins. FEBS Lett 1974; 38 (3): 247–258.
Chen SH, Habib G, Yang CY, Gu ZW, Lee BR, Weng SA, Silberman SR, et al. Apolipoprotein B-48 is the product of a messenger RNA with an organ-specific inframe stop codon. Science 1987; 238 (4825): 363–366.
Chan L, VanTuinen P, Ledbetter DH, Daiger SP, Gotto AM, Jr., Chen SH. The human apolipoprotein B-100 gene: A highly polymorphic gene that maps to the short arm of chromosome 2. Biochem Biophy Res Commun 1985; 133 (1): 248–255.
Baker WC, Dayhoff MO. Evolution of lipoproteins deduced from protein sequence data. Comp Biochem Physiol 1977; 57 (4): 309–315.
Karathanasis SK, Zannis VI, Breslow JL. Isolation and characterization of the human apolipoprotein A-I gene. Proc Natl Acad Sci USA 1983; 80 (20): 6147–6151.
Fielding CJ. Monoglyceride hydrolase activities of rat plasma and platelets. Their properties and roles in the activity of lipoprotein lipase. J Biol Chem 1981;256(2):876–881.
Schmitz G, Assmann G, Robenek H, Brennhausen B. Tangier disease: A disorder of intracellular membrane traffic. Proc Natl Acad Sci USA 1985;82(18):6305–6309.
Yang CY, Lee FS, Chan L, Sparrow DA, Sparrow JT, Gotto AM, Jr. Determination of the molecular mass of apolipoprotein B-100. A chemical approach. Biochem J 1986;239(3):777–780.
Chen SH, Yang CY, Chen PF, et al. The complete cDNA and amino acid sequence of human apolipoprotein B-100. J Biol Chem 1986;261(28)12918–12921.
Sparrow JT, Sparrow DA, Culwell AR, Gotto AM, Jr. Apolipoprotein E: Phospholipid binding studies with synthetic peptides containing the putative receptor binding region. Biochemistry 1985;24(24):6984–6988.
Forgez P, Gregory H, Young JA, Knott T, Scott J, Chapman MJ. Identification of surface-exposed segments of apolipoprotein B-100 in the LDL particle. Biochem Biophys Res Commun 1986;140(1):250–257.
Soria LF, Ludwig EH, Clarke HR, Vega GL, Grundy SM, McCarthy BJ. Association between a specific apolipoprotein B mutation and familial defective apolipoprotein B-100. Proc Natl Acad Sci USA 1989;86(2):587–591.
Teng B, Sniderman AD, Soutar AK, Thompson GR. Metabolic basis of hyperapobetalipoproteinemia. Turnover of apolipoprotein B in low density lipoprotein and its precursors and subfractions compared with normal and familial hypercholesterolemia. J Clin Invest 1986;77(3):663–672.
Kita T, Brown MS, Bilheimer DW, Goldstein JL. Delayed clearance of very low density and intermediate density of lipoproteins with enhanced conversion to low density lipoprotein in WHHL rabbits. Proc Natl Acad Sci USA 1982;79 (18): 5693–5697.
Williams RR, Hunt SC, Hopkins PN, Stults BM, Wu LL, et al. Familial dyslipidemic hypertension. Evidence from 58 Utah families for a syndrome present in approximately 12% of patients with essential hypertension. JAMA 1988;259(24): 3579–3586.
Krause BR, Newton RS. Apolipoprotein changes associated with the plasma lipid-regulating activity of gemfibrozil in cholesterol-fed rabbits. J Lipid Res 1985;26(8):940–949.
Lussier Cacan S, Bard JM, Boulet L, Nestruck AC, Grothe AM, Fruchart JC, et al. Lipoprotein composition changes induced by fenofibrate in dysbetalipoproteinemia type III. Atherosclerosis 1989;78(2–3):167–182.
Kodama T, Freeman M, Rohrer L, et al. Type I macrophage scavenger receptor contains a-helical and collagen-like coiled coils. Nature 1990;343:531–535.
Steinbrecher UP, Witztum JL, Parthasarathy S, Steinberg D. Decrease in reactive amino groups during oxidation or endothelial cell modification of LDL. Correlation with changes in receptor-mediate catabolism. Arteriosclerosis 1987;7 (2) 135–143.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1990 Kluwer Academic Publishers
About this chapter
Cite this chapter
Gotto, A.M. (1990). Apolipoproteins and metabolism in atherosclerosis. In: Descovich, G., Gaddi, A., Magri, G., Lenzi, S. (eds) Atherosclerosis and Cardiovascular Disease. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-0731-7_14
Download citation
DOI: https://doi.org/10.1007/978-94-009-0731-7_14
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-010-6814-7
Online ISBN: 978-94-009-0731-7
eBook Packages: Springer Book Archive