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Assessment of Myocardial Viability with PET

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Clinical PET

Part of the book series: Developments in Nuclear Medicine ((DNUM,volume 28))

Abstract

Less than 20 years ago, contractile dysfunction of the myocardium in the distribution territory of a stenosed coronary artery was thought to represent either irreversible damage of myocytes due to myocardial infarction and necrosis, or the effects of transient ischemia. However, during the last decade, experimental and clinical studies demonstrated that regional contractile dysfunction may also occur in the absence of myocardial infarction and may persist for a long time after cessation of ischemia with spontaneous normalization of function. Regional dysfunction in viable myocardium may be either temporary and spontaneously reversible following early reperfusion of a previously occluded vessel (myocardial “stunning” [1]) or sustained in the presence of chronic resting hypoperfusion and potentially reversible following restoration of blood flow by coronary revascularization (myocardial “hibernation” [2]).

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Authors
  1. Juergen vom Dahl
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Editors and Affiliations

  1. Department of Nuclear Medicine, Eberhard-Karls-University, Roentgenweg 13, D-72076, Tuebingen, Germany

    Roland B. Bares

  2. INB-CNR, Department of Nuclear Medicine, University of Milan, Scientific Institute H.S., Via Olgettina 60, Raffaele, Milan, I- 20132, Italy

    Giovanni Lucignani

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© 1996 Kluwer Academic Publishers

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vom Dahl, J. (1996). Assessment of Myocardial Viability with PET. In: Bares, R.B., Lucignani, G. (eds) Clinical PET. Developments in Nuclear Medicine, vol 28. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-0309-8_3

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  • DOI: https://doi.org/10.1007/978-94-009-0309-8_3

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-6624-2

  • Online ISBN: 978-94-009-0309-8

  • eBook Packages: Springer Book Archive

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