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Reconstruction of Bladder Innervation Above the Level of Spinal Cord Injury for Inducing Urination by Abdomen-to-Bladder Reflex Contractions

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Functional Bladder Reconstruction Following Spinal Cord Injury via Neural Approaches
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Abstract

Spinal-cord injuries (SCIs) can seriously damage somatic motion and sensation. However, they can also cause visceral neurogenic dysfunctions, among which compromised micturition, compromised defecation, and disturbances when engaging in coitus are the most common problems. The hyper-reflexic spastic bladder is believed to be a more significant dysfunction because the high intravesical pressure in the bladder can result in damage to the bladder–ureter countercurrent multiplier system and the kidneys; these major complications can cause death in SCI patients [1].

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References

  1. Selzman AA, Hampel N. Urologic complications of spinal cord injury. Urol Clin North Am. 1993;20:453–64.

    PubMed  CAS  Google Scholar 

  2. Cass AS, Luxenberg M, Johnson CF, Gleich P. Management of the neurogenic bladder in 413 children. J Urol. 1984;132:521–5.

    PubMed  CAS  Google Scholar 

  3. Mitchell ME, Kulb TB, Backes DJ. Intestinocystoplasty in combination with clean intermittent catheterization in the management of vesical dysfunction. J Urol. 1986;136:288–91.

    PubMed  CAS  Google Scholar 

  4. Brindley GS, Polkey CE, Rushton DN, Cardozo L. Sacral anterior root stimulators for bladder control in paraplegia: the first 50 cases. J Neurol Neurosurg Psychiatry. 1986;49:1104–14.

    Article  PubMed  CAS  Google Scholar 

  5. Xiao CG, de Groat WC, Godec CJ, Dai C, Xiao Q. “Skin-CNS-bladder” reflex pathway for micturition after spinal cord injury and its underlying mechanisms. J Urol. 1999;162:936–42.

    Article  PubMed  CAS  Google Scholar 

  6. Hou CL, Zhong HB, Zhang SM, Chen AM, Liu ZD, Liu MX. Establishing an artificial somato-CNS-bladder reflex arc to restore controlled micturition in spinal cord injuries: a preliminary report. Acad J Second Mil Med Univ (Chin). 2000;21:87–9.

    Google Scholar 

  7. Lin H, Hou C, Zhen X. Bypassing spinal cord injury: surgical reconstruction of afferent and efferent pathways to the urinary bladder after conus medullaris injury in a rat model. J Reconstr Microsurg. 2008;24:575–81.

    Article  PubMed  Google Scholar 

  8. Lin H, Hou CL, Zhong G, Xie Q, Wang S. Reconstruction of reflex pathways to the atonic bladder after conus medullaris injury: preliminary clinical results. Microsurgery. 2008;28:429–35.

    Article  PubMed  Google Scholar 

  9. Chuang DC, Chang PL, Cheng SY. Root reconstruction for bladder reinnervation: an experimental study in rats. Microsurgery. 1991;12:237–45.

    Article  PubMed  CAS  Google Scholar 

  10. Benevento BT, Sipski ML. Neurogenic bladder, neurogenic bowel, and sexual dysfunction in people with spinal cord injury. Phys Ther. 2002;82:601–12.

    PubMed  Google Scholar 

  11. Frankel HL, Coll JR, Charlifue SW, Whiteneck GG, Gardner BP, Jamous MA, et al. Long-term survival in spinal cord injury: a fifty year investigation. Spinal Cord. 1999;36:266–74.

    Article  Google Scholar 

  12. Brindley GS. The first 500 patients with sacral anterior root stimulator implants: general description. Paraplegia. 1994;32:795–805.

    Article  PubMed  CAS  Google Scholar 

  13. Xiao CG, Godec CJ. A possible new reflex pathway for micturition after spinal cord injury. Paraplegia. 1994;32:300–7.

    Article  PubMed  CAS  Google Scholar 

  14. Sievert KD, Xiao CG, Hennenlotter J, Seibold J, Merseburger AS, Kaminskie J, et al. Voluntary micturition after intradural nerve anastomosis. Urology A. 2005;44:756–61.

    Article  Google Scholar 

  15. Hou CL, Zhong HB, Zhang SM, Liu MX. Experimental study on establishment of artificial bladder reflex arc after spinal cord injury. Chin J Reparative Reconstr Surg (Chin). 2000;14:10–3.

    CAS  Google Scholar 

  16. Zheng XY, Hou CL, Zhong HB, Xu RS, Chen AM, Xu Z. Reconstructed bladder innervation below the level of spinal cord injury: the kneetendon to bladder artificial reflex arc. J Spinal Cord Med. 2009;32:79–85.

    PubMed  Google Scholar 

  17. Wang HZ, Li SR, Wen C, Xiao CG, Su BY. Morphological changes of cholinergic nerve fibers in the urinary bladder after establishment of artificial somatic autonomic reflex arc in rats. Neurosci Bull. 2007;23:277–81.

    Article  PubMed  Google Scholar 

  18. Wang JW, Hou CL, Lu N. Long-term functional study on the artificial bladder reflex arc established by abdominal reflex after spinal cord injury. Chin J Microsurg. 2002;25:280–4.

    Google Scholar 

  19. Zhong GB, Hou CL, Wang SB. Experminent study on the artificial bladder reflex arc established in therapy of flaccid bladder after spinal cord injury. Chin J Repar Reconstr Surg. 2006;20:812–5.

    Google Scholar 

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Correspondence to Chunlin Hou M.D. .

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Lin, H., Wang, J., Zhong, G., Hou, C. (2014). Reconstruction of Bladder Innervation Above the Level of Spinal Cord Injury for Inducing Urination by Abdomen-to-Bladder Reflex Contractions. In: Hou, C. (eds) Functional Bladder Reconstruction Following Spinal Cord Injury via Neural Approaches. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-7766-8_8

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  • DOI: https://doi.org/10.1007/978-94-007-7766-8_8

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