Abstract
Understanding how proteins assemble into their final shapes (or “fold”) has been a grand challenge of computational biology for decades. MSM methods have allowed, for the first time, the direct simulation of how proteins fold on the microsecond to 10’s of millisecond timescale, yielding novel insight into the process.
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Pande, V.S. (2014). Understanding Protein Folding Using Markov State Models. In: Bowman, G., Pande, V., Noé, F. (eds) An Introduction to Markov State Models and Their Application to Long Timescale Molecular Simulation. Advances in Experimental Medicine and Biology, vol 797. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-7606-7_8
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DOI: https://doi.org/10.1007/978-94-007-7606-7_8
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-007-7605-0
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