Abstract
General regularities of low dose-rate radiation effects were determined on plant seeds in laboratory experiments. Three groups of seeds were tested: young, old, and heat-stressed because aging and high temperature are the usual natural factors. Statistical modelling has shown that the adaptation processes have three components: primary injuring, late damaging, and selection, which is more intensive in the sensitive subpopulation of seeds. The relationship between inter- and intracellular processes was analyzed. The combination of radiation and heat stresses dramatically increases late damaging and selection at non-optimal temperatures which do not exceed the norm limits. This approach allows one to estimate the risks of instabilities accompanied by the accumulation of abnormalities, selection, and death of seedlings.
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Notes
- 1.
After the Second World War, Timofeeff-Ressovsky was sent by the regime first to a Stalinist camp near Karaganda, and then to Site No. 0215, a secret scientific laboratory in the South Urals. There, he headed pioneering studies of the biological effect of radionuclides and their impact on ecosystems. Many investigators who later gained scientific repute worked at the Timofeeff-Ressovsky laboratory; the others came there for discussion. Among these scientists were V.I. Korogodin, G.G. Polikarpov, A.A. Lyapunov and others.
- 2.
The interval of middle-lethal doses corresponds to Fig. 4.1a
- 3.
The cells stimulated to proliferate are involved in the distributions.
References
Atayan RR (1987) Interaction of factors modifying the radiosensitivity of dormant seeds: a review. Int J Radiat Biol Relat Stud Phys Chem Med 52:827–845
Barton L (1962) Seed preservation and longevity. Mark and Phyll Publ, London
Boei JJ, Vermeulen S, Natarajan AT (1996) Detection of chromosomal aberrations by fluorescence in situ hybridization in the first three postirradiation divisions of human lymphocytes. Mutat Res 349:127–135
Burdon RH, Gill V, Rice-Evans C (1989) Cell proliferation and oxidative stress. Free Radical Res Commun 7:149–159
Buzzard KA, Giaccia AJ, Killender M et al (1998) Heat shock protein 72 modulates pathways of stress-induced apoptosis. J Biol Chem 273:17147–17153
Davis W Jr, Ronai Z, Tew KD (2001) Cellular thiols and reactive oxygen species in drug-induced apoptosis. J Pharmacol Exp Theor 296:1–6
Dineva SB, Abramov VI, Shevchenko VA (1993) Genetic effects of lead nitrate on seeds of chronically irradiated populations of Arabidopsis thaliana. Genetika 29:1914–1920
Evseeva TI, Geras’kin SA (2001) Combined effect of radiation and non-radiation factors on Tradescancia. Ural Division of RAS, Ekaterinburg (Russian)
Feller W (1957) An introduction to probability theory and its applications. Wiley/Chapman & Hall, Limited, New York/London
Florko BV, Korogodina VL (2007) Analysis of the distribution structure as exemplified by one cytogenetic problem. PEPAN Lett 4:331–338
Geras’kin SA, Sarapultsev BI (1993) Automatic classification of biological objects by the radiation stability level. Autom Telemech 2:183 (Russian)
Glotov NV, Zhivotovskjy LA, Khovanov NV et al (1982) Biometrics. Leningrad State University, Leningrad (Russian)
Gudkov IN (1985) Cell mechanisms of postradiation repair in plants. Naukova Dumka, Kiev (Russian)
Hanawalt PS (1987) On the role of DNA damage and repair process in aging: evidence for and against. In: Werner HR, Butler RN, Sprott RL et al (eds) Modern biological theories of aging. Raven, New York, pp 183–198
Kim JK, Petin VG, Zhurakovskaya GP (2001) Exposure rate as a determinant of the synergistic interaction of heat combined with ionizing or ultraviolet radiation in cell killing. J Radiat Res (Tokyo) 42:361–369
Korogodina VL, Florko BV, Korogodin VI (2005) Variability of seed plant populations under oxidizing radiation and heat stresses in laboratory experiments. IEEE Trans Nucl Sci 52:1076–1083
Korogodina VL, Florko BV, Osipova LP (2010) Adaptation and radiation-induced chromosomal instability studied by statistical modeling. Open Evol J 4:12–22
Korogodina VL, Florko BV (2007) Evolution processes in populations of plantain, growing around the radiation sources: changes in plant genotypes resulting from bystander effects and chromosomal instability. In: Mothersill C, Seymour C, Mosse IB (eds) A challenge for the future. Springer, Dordrecht, pp 155–170
Korogodina VL, Panteleeva A, Ganicheva I et al (1998) Influence of the low gamma-irradiation dose rate on mitosis and adaptive response in meristem cells of pea seedlings. Radiats Biol Radioecol 38:643–649 (Russian)
Luchnik NV (1958) Influence of low dose irradiation on mitosis in pea. Newslett Ural Department Moscow Soc Nat Investig 1:37–49 (Russian)
MacCarrone M, Van Zadelhoff G, Veldink GA et al (2000) Early activation of lipoxygenase in lentil (Lens culinaris) root protoplasts by oxidative stress induces programmed cell death. Eur J Biochem 267:5078–5084
Moskalev AA, Plyusnina EN, Shaposhnikov MV (2011) Radiation hormesis and radioadaptive response in Drosophila melanogaster flies with different genetic backgrounds: the role of cellular stress-resistance mechanisms. Biogerontology 12(3):253–263
Mothersill C, Kadhim MA, O'Reilly S et al (2000a) Dose- and time-response relationships for lethal mutations and chromosomal instability induced by ionizing radiation in an immortalized human keratinocyte cell line. Int J Radiat Biol 76:799–806
Mothersill C, Stamato TD, Perez ML et al (2000b) Involvement of energy metabolism in the production of ‘bystander effects’ by radiation. Br J Cancer 82:1740–1746
Mothersill C, Seymour CB (2000) Genomic instability, bystander effect and radiation risks: implications for development of protection strategies for man and environment. Radiats Biologija Radioecologija 40:615–620
Mothersill C, Seymour CB (2004) Radiation-induced bystander effects and adaptive responses – the Yin and Yang of low dose radiobiology? Mutat Res 568:121–128
Navashin M, Gerasimova E (1935) The origin and reasons of mutations. Biol J 4:593–642 (Russian)
Ohba K (1961) Radiation sensitivity of pine seeds of different water content. Hereditas 47:283–294
Orr HA (2006) The distribution of fitness effects among beneficial mutations in Fisher’s geometric model of adaptation. J Theor Biol 238:279–285
Petin VG, Kim JK, Zhurakovskaya GP et al (2002) Some general regularities of synergistic interaction of hyperthermia with various physical and chemical inactivating agents. Int J Hyperthermia 18(1):40–49
Petin VG, Zhurakovskaia GP, Pantiukhina AG et al (1999) Small doses and synergistic interaction of environmental factors. Radiats Biol Radioecol 39(1):113–126 (Russian)
Pinzino C, Capocchi A, Galleschi L et al (1999) Aging, free radicals, and antioxidants in wheat seeds. J Agric Food Chem 47:1333–1339
Preobrazhenskaya E (1971) Radioresistance of plant seeds. Atomizdat, Moscow (Russian)
Rainwater DT, Gossett DR, Millhollon EP et al (1996) The relationship between yield and the antioxidant defense system in tomatoes grown under heat stress. Free Radic Res 25:421–435
Seymour CB, Mothersill C (2000) Relative contribution of bystander and targeted cell killing to the low-dose region of the radiation dose–response curve. Radiat Res 153:508–511
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Korogodina, V.L., Florko, B.V., Osipova, L.P. (2013). Non-linearity Induced by Low-Dose Rates Irradiation. Lab Experiments on Pea Seeds. In: Radiation-Induced Processes of Adaptation. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-6630-3_4
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