Abstract
Malaria is one of the most important parasitic infections that account for an estimated prevalence of 500 million and more than one million casualties per annum. Due to the development of drug resistance in malarial parasites, it is cumbersome to treat and prevent malaria infection. Recently, development of resistance against artemisinin and its derivatives are documented from Cambodia-Thailand border. Keeping all that in mind there is an urgent need to develop new antimalarials from traditional medicine i.e. phytomedicine. This chapter summarises the approaches in phytomedicine to develop potential anti-malarial candidates. Based on in vivo and in vitro studies reporting activity against malarial parasites there is no doubt about the possibility to discover novel anti-malarials of plant origin in near future that could even combat the recent developing drug resistance.
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Raza, A., Shujatullah, F., Khan, H.M., Shahid, M., Malik, A. (2013). Malaria and Phytomedicine. In: Shahid, M., Shahzad, A., Malik, A., Sahai, A. (eds) Recent Trends in Biotechnology and Therapeutic Applications of Medicinal Plants. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-6603-7_11
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