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The Nucleolus of Dictyostelium and Other Lower Eukaryotes

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Proteins of the Nucleolus

Abstract

The nucleolus is a multifunctional organelle involved in ribosomal subunit biogenesis as well as a multitude of other cellular functions. Although the mammalian nucleolus has been studied extensively and a multitude of nucleolar proteins have been identified relatively little is known about the nucleolus in lower eukaryotes and relatively few nucleolar proteins have been examined. The lower eukaryote Dictyostelium is a model system used to study several cellular processes such as growth, chemotaxis, differentiation, and development. In recent years Dictyostelium has also been used to study several human diseases such as Alzheimer’s disease and Huntington’s disease. However despite its extensive study relatively little is known about its nucleolus. It is important to examine the nucleolus of Dictyostelium and other lower eukaryotes in order to gain a better understanding of the structure and function of this fascinating multifunctional organelle. This chapter will focus on the nucleolus and nucleolar proteins in Dictyostelium and will then examine the nucleoli of other lower eukaryotes.

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  1. City College of New York, 160 Convent Ave. Marshak Building, rm.1221, New York, NY, 10031, USA

    Andrew Catalano

  2. Biology Department, University of Toronto at Mississauga, 3359 Mississauga Road, L5L1C6, Mississauga, ON, Canada

    Danton H. O’Day

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    Danton H O'Day

  2. , Biology, University of Toronto at Mississauga, Mississauga Rd. 3359, Mississauga, L5L1C6, Ontario, Canada

    Andrew Catalano

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Catalano, A., O’Day, D.H. (2013). The Nucleolus of Dictyostelium and Other Lower Eukaryotes. In: O'Day, D., Catalano, A. (eds) Proteins of the Nucleolus. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-5818-6_4

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