Abstract
Xanthogranuloma (cholesterol granuloma) in the sellar region was traditionally regarded as a hallmark of craniopharyngioma, but it can be associated with other lesion including pituitary adenomas. In adenomas, xanthogranulomas may develop in large tumors, probably following hemorrhagic processes, and patients present with various degrees of pituitary insufficiencies. On MRI, xanthogranulomas typically exhibit mixed signal intensities with heterogeneous gadolinium enhancement, reflecting their complex histological features. The most characteristic finding is cholesterol clefts that show T1-high and T2-low signal intensities. Fine evaluation of MRI findings is required for the accurate diagnosis and the appropriate surgical intervention that may improve pituitary function.
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Nishioka, H., Shibuya, M. (2013). Xanthogranulomas Associated with Pituitary Adenomas: Magnetic Resonance Imaging. In: Hayat, M. (eds) Tumors of the Central Nervous System, Volume 10. Tumors of the Central Nervous System, vol 10. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-5681-6_9
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DOI: https://doi.org/10.1007/978-94-007-5681-6_9
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